The Mumps Outbreak Epidemiology in Zambezi Region

Research Article | DOI: https://doi.org/10.31579/2690-8794/278

The Mumps Outbreak Epidemiology in Zambezi Region

  • Sirka M Mandema 1,2
  • Jacob A Sheehama 3*
  • Teopolina Enkono 4

1 Ministry of Health and Social Services, Kavango East Region, Namibia.

2 Namibia Field Epidemiology and Laboratory Training Program.

3 Department of Human, Biological & Translational Medical Sciences, School of Medicine, University of Namibia.

4 Department of Nursing Sciences, I-Care Health Training Institute, Namibia.

*Corresponding Author: Jacob A Sheehama, Ministry of Health and Social Services, Kavango East Region, Namibia.

Citation: Sirka M Mandema, Jacob A Sheehama, Teopolina Enkono, (2026), The Mumps Outbreak Epidemiology in Zambezi Region, Clinical Medical Reviews and Reports, 8(2); DOI:10.31579/2690-8794/278

Copyright: © 2026, Jacob A. Sheehama. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Received: 10 January 2026 | Accepted: 27 January 2026 | Published: 10 February 2026

Keywords: mumps; outbreak; epidemiology; vaccination; Zambezi region; Namibia

Abstract

Background and aim: Mumps is a vaccine-preventable viral disease characterized by swelling of the salivary glands and potential complications. beginning February 13, 2023, an outbreak of mumps occurred in Zambezi Region, Namibia, and is ongoing. We investigated to describe the epidemiology of the outbreak, actively identify cases, implement health interventions, and inform effective public health strategies.

Material and Methods: A descriptive cross-sectional study was conducted to analyse mumps cases in the Zambezi region. Clinical diagnoses case definition was used. A clinical case was defined as acute onset of gland swelling lasting ≥2 days. Data were collected from health facilities and schools, including demographic information and diagnosis. A line list was generated, and data were analysed descriptively using descriptive model.

Results: A total of 2625 mumps cases were reported in the Zambezi Region, between February 13th, 2023, and October 8th, 2023. Interventions included active case searches, supportive treatment, health education, and advising patients to self-isolate for 7 days.  Age group under five years experienced the highest attack rate 3.62%, followed by under 15 years with 2.98% and the least attack rate was observed in 15 years and above with 0.80%. Females experienced slightly higher infection rates at 50.1%. Zambezi region saw a significant number of mumps cases reported in various villages, Chotto led the list with 308 cases, followed by Cowboy with 246 cases. The outbreak displayed progressively increasing peaks in the epidemiological curve, indicating ongoing transmission. No fatalities and complications were reported, p < 0.01).

Discussion: The outbreak mainly impacted school-aged children. No deaths or severe cases occurred. The lack of mumps vaccination in the national program might have amplified the outbreak. To address Zambezi's situation, introducing mumps vaccination and including it in surveillance for early detection is crucial. Ongoing case searches and immediate isolation remain essential.

Introduction

On April 5, 2023, The Senior Programme Officer observed an increase in mumps cases, reported from the health facilities on a weekly basis. The first two suspected mumps cases were recorded in week 7 (13/02/2023 -19/02/2023), followed by three instances each in weeks 8 and 9. A peak was reached in week 10 (06.03.2023-12.03.2023), when the region reported 27 cases, and week 11 saw 56 cases. Weeks 12 and 13 each had 31 and 51 cases, respectively, reported.  The Zambezi region has seen a rise in cases since then. There has been a total of 2625 cases of the mumps reported in Zambezi since February 2023. So yet, there have been no documented fatalities or mortalities. The ages of the cases recorded range from 11 months to 45 years.

The rise in the number of mumps cases prompted the Senior Program officer to call for an emergency meeting on the same date April 5th, 2023. The meeting was attended by the Senior Medical Officer, Environmental Officer, Health Information System officer, Infection Prevention and Control Nurse, and Namibia Field Epidemiologist resident. The meeting's objectives were to discuss the increase in mumps cases, establish a mumps response team, and address the outbreak.

During the meeting a team consisting of the Environmental officer, Senior Program Officer, IPC nurse, HIS officer and Nam FELTP resident was formed to respond to the outbreak. On the same date April 5th, 2023, the team started responding to the outbreak.

Mumps, a short-term illness that primarily affects children and young adults, is caused by a specific paramyxovirus with just one serotype [1]. Human beings are the exclusive known hosts for the mumps virus, and it spreads through direct contact or the inhalation of airborne droplets from infected individuals’ upper respiratory tract [2]. Mumps is most commonly seen in children aged 5 to 9 years, although adolescents and adults can also be affected. The disease typically commences with nonspecific symptoms, including muscle pain, headaches, fatigue, and a mild fever, following an incubation period of 2 to 4 weeks. These symptoms are subsequently followed by the swelling of one or both parotid salivary glands, with other salivary glands affected in roughly 10% of cases [3]. 

Normally, mumps is a mild, self-limiting condition and generally resolves without lasting consequences [1]. However, it can lead to complications like orchitis, oophoritis, mastitis, meningitis, encephalitis, pancreatitis, and even hearing impairment. These complications can occur in the absence of parotitis and are less frequent in vaccinated individuals. Notably, some mumps-related complications are more frequently observed in adults compared to children [4].

Mumps is not a notifiable disease and is not included in any formal surveillance programme. Students in schools, health care workers, international travellers or people living in a community with a mumps outbreak are at high risk of getting mumps. There is no treatment for mumps, Acetaminophen or ibuprofen can ease fever and pain [5].

Vaccination is the best way to prevent mumps and mumps complications. This vaccine is included in the combination measles-mumps-rubella (MMR) and measles-mumps-rubella-varicella (MMRV) vaccines. Two doses of mumps vaccine are 88% (range 32% to 95%) effective at preventing the disease; one dose is 78% (range 49% to 91%) effective [4]. In Namibia the mumps vaccine is not part of the immunisation program yet.

Object of the outbreak response 

The aim and objectives of this study was to conduct active case search at sites that have reported mumps cases in Zambezi region, 2023, it is focused on the task to generate a line list of mumps cases in Zambezi region, 2023. It is with final aim to establish responsive health interventions including case management and community education in Zambezi region, 2023.

Materials and Methods

Study Design

A descriptive study of mumps cases in Zambezi region was conducted. All mumps cases included in the study were clinically diagnosed.

Population

The Zambezi Region have a population of 142,373, and constituted of 8 constituencies. The outbreak was declared for the whole region, stemming a population of 142,373. The patients who were diagnosed at the health facilities and the students from 5 schools namely: Naleli Toddler’s University, Ngweze Primary School, Alfea Sampofu Primary School, Greenwell Matongo Primary School, and Thobias Hainyeko Primary School who were screened for mumps from the 6th to 14th April 2023.

Data Collection

Mumps cases were identified using a clinical case definition by the health care providers at the health facilities and schools. The outbreak response team lead received an alert from the health facilities about the schools reporting mumps cases, the response team visited the school to conduct screening.

Demographic information including name, age, gender, and diagnosis were collected by the health care providers from the patients at the health facilities and schools, and line lists were generated.

Case definitions 

Clinical Case Definition: An illness characterized by acute onset of unilateral or bilateral self-limited swelling of the parotid or other salivary gland(s) lasting at least 2 days, and without other apparent cause, onset after February, 13th, 2023 in Zambezi Region (6). 

Clinically compatible illness: An illness clinically compatible with mumps is characterized by: parotitis or other salivary gland swelling, aseptic meningitis, encephalitis, hearing loss, orchitis, oophoritis, mastitis, or pancreatitis, onset after February 13th, 2023 in Zambezi Region (6).

Suspect: Parotitis, acute salivary gland swelling, orchitis, or oophoritis unexplained by another more likely diagnosis, OR 

A positive lab result with no mumps clinical symptoms (with or without epidemiological linkage to a confirmed or probable case) (6). 

Probable: Acute parotitis or other salivary gland swelling lasting at least 2 days, or orchitis or oophoritis unexplained by another more likely diagnosis, in: A person with a positive test for serum anti-mumps immunoglobulin M (IgM) antibody, OR 

A person with epidemiologic linkage to another probable or confirmed case or linkage to a group/community defined by public health during an outbreak of mumps (6). 

Confirmed: A positive mumps laboratory confirmation for mumps virus with reverse transcription polymerase chain reaction (RT-PCR) or culture in a patient with an acute illness characterized by any of the following: Acute parotitis or other salivary gland swelling, lasting at least 2 days (6).

Data Analysis

Microsoft excel 97-2003 and SSPS were used to analyse the data, descriptive statistics were used to analyse the demographic characteristics of mumps cases and distribution of cases were presented through graphs, and tables.

Ethical consideration

Permission to conduct the outbreak response was obtained from the Ministry of Health and Social Services, Regional Management team and Regional Surveillance Officer.

Confidentiality was maintained by keeping the data in the laptop which has a password known only by the writer and the names of the patients were not included in the analysis.

Results

Overview of the Outbreak

A total of 2625 mumps cases were reported during this period. The cases consist of both children and adults, with ages ranging from 11 months to 45 years. The attack rate was highest among the under-fives 3.62%, the least attack rate is recorded amongst the age group fifteen and above with 0.80%. No fatalities have been reported to date. Majority who had mumps were females, 1316 (50.1%).

VariableParameterNumber of casesPercentage (%)PopulationAttack rate (%)
Age groups (Years)Under fives66525.3183593.62
Under fifteen171265.2574072.98
Fifteen and above2489.431,0970.80
GenderFemale131650.1  
Male130949.9  

Table 1: Sociodemographic characteristics of mumps cases reported in Zambezi region, 13 February to 16 July 2023 (n=2625).

In 2023, the Zambezi region saw a significant number of mumps cases reported in various villages. The top 10 villages with the highest mumps case counts were as follows: Chotto led the list with 308 cases, followed by Cowboy with 246 cases. Macaravani West reported 102 cases, while Dairy had 79 cases, and Linyanti recorded 76 cases. Further down the list, Mission reported 45 cases, Ngweze had 43, Liselo reported 42, and Muyako had 38 cases. Additionally, both Macaravani East and New NHE reported 37 cases each, making it a tie for the 10th position in the list of villages significantly affected by the mumps outbreak in the Zambezi region.

Figure 1: Distributions of Mumps cases per village in Zambezi region, 2023.

Distribution of mumps cases per epidemiological week in Zambezi region, 2023.

The region reported its first cases in week 7 (13/02/23 -19/02/2023) 2 (0.1%), since then the cases started spreading from person to person, the epi curve graph is progressively having taller peaks, starting from week 10 (17/05/23 -23/05/23) to week 28 (10/07/23 -16/07/23). Week 16 (17/05/2023 -23/05/23) reported the highest cases 158 (8.2%), refer to Fig.1. (n=2625)

Figure 2: Distribution of mumps cases by epidemiological week in Zambezi region, 2023.

Socio-demographic characteristics of learners who were screened during mumps outbreak response in Zambezi Region, 2023.

The age range of 10 to 14 years exhibited a significant prorpotion of mumps cases, with 51 (20%) cases, and there was a higher proportion of mumps cases among males, with 42(22%) cases. Among the affected individuals, learners at Tobias Hainyeko Primary School were the most impacted, with a notably high proportion of mumps cases, accounting for 29 (36%) cases (see Table 2).

Age (years)Total ScreenedMumps casesPercentage (%)
5 - 91863317
10 - 142525120
Gender   
Female2494217
Male1894222
School    
Greenwell Matongo Primary School2213214
Alfe Sampofu40923
Tobias Hainyeko Primary School802936
Ngweze Primary School931415
Sampofu Combined School400

Table 2: Sociodemographic characteristics of learners who were screened during mumps outbreak response in Zambezi region, 2023 (n=438).

Distribution of diseases/conditions among learners during mumps outbreak response at schools in Zambezi region, 2023.

High proportion 349 (80%) learners were affected with tonsils followed by 84 (19%) who were affected by mumps (see Figure 2).

Figure 3: Distribution of diseases/conditions among learners during mumps outbreak response at schools in Zambezi region, 2023 (n=438).

Discussion

A total of 2,625 mumps cases were reported during this period, encompassing both children and adults with ages ranging from 11 months to 45 years. The attack rate was highest among children under five years old, at 3.62%, while the lowest attack rate was observed in individuals aged fifteen and above, with a rate of 0.80%. This contrasts with existing literature, which typically reports mumps cases as frequent among children aged 5-9, though adolescents and adults may also be affected [3]. Literature is inconsistent with the findings of the study which was done in European union, were the highest proportion of mumps cases were observed among those aged five to nine years, increasing to 15 years and above [7]. Importantly, there have been no reported fatalities as of the latest data, and a majority of the mumps cases were females, comprising 50.1% of the total cases. 

The outbreak affected various villages in the Zambezi region, with the top 10 villages reporting significant mumps case counts. Among these villages, Chotto had the highest number of cases at 308, followed by Cowboy with 246 cases. The outbreak primarily impacted schools, with many cases occurring among school-going children under five years and under 15 years. This pattern is consistent with the literature, which suggests that students in schools are at risk of contracting mumps [5]. No fatalities and serious complications have been reported to date. 

The epidemiological curve demonstrates progressively taller peaks, consistent with the concept in literature that such peaks in an outbreak signify the spread of cases from one person to another [8]. In this outbreak the cases are spreading from one person to another after an incubation period. 

Moreover, a high proportion of learners, 80%, were affected by tonsillitis, with 19?fected by mumps. The spread of mumps cases may be associated with specific social settings, particularly schools, where children are in close proximity, sharing food and items. Additionally, the lack of vaccination programs against mumps in Namibia may contribute to the spread of mumps cases.

The mumps outbreak is still ongoing, which pose challenges in terms of disease control especially in school. The school going children must stay at home for 5 or 7 days to prevent the spread of the disease to others, which is leading to missing out on important information that others are been taught.

The disease is also placing a burden on health services resources as it has highlighted the need for robust surveillance systems and public health interventions such as introduction of mumps vaccines. No complications or fatalities have been recorded so far

Limitations

As any other outbreak study this bone faced many limitations, such as methodological and biases mainly. Mumps is not included in the disease surveillance system, information such as cases per health facility is not available in the District Health Information System (DHIS2). 

Not much literature has been done on mumps.

Conclusion

This report has examined a recent mumps outbreak in Zambezi region, highlighting its epidemiology, transmission patterns, and impact on public health. By implementing the recommended control measures, especially introduction of mumps vaccines and enhancing surveillance systems, can effectively prevent and manage current and future mumps outbreaks, ultimately protecting the health and well-being of its population.

Recommendations

The republic of Namibia (Family health, National level focal person) should consider proposing the introduction and incorporating the mumps vaccine in the immunization programs and conducting immunization campaigns in the affected communities. The regional, district team and health facilities should continue with surveillance activities, health education and control measures.

Public Health Actions

The outbreak response team together with community health extension workers to strengthen health education in communities as well as continue with awareness through radio talks and community meetings with the headmen. Health care providers to continue with isolation of mumps cases for at least 7 days in either community or healthcare setting. The public to use standard precautions and droplet precautions.

Outreach team to continue with the implementation of mumps active case search in the communities as well as schools within the vicinity visited daily.

References

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Zsuzsanna Bene

Dealing with The Journal of Neurology and Neurological Surgery was very smooth and comprehensive. The office staff took time to address my needs and the response from editors and the office was prompt and fair. I certainly hope to publish with this journal again.Their professionalism is apparent and more than satisfactory. Susan Weiner

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Dr Susan Weiner

My Testimonial Covering as fellowing: Lin-Show Chin. The peer reviewers process is quick and effective, the supports from editorial office is excellent, the quality of journal is high. I would like to collabroate with Internatioanl journal of Clinical Case Reports and Reviews.

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Lin-Show Chin

My experience publishing in Psychology and Mental Health Care was exceptional. The peer review process was rigorous and constructive, with reviewers providing valuable insights that helped enhance the quality of our work. The editorial team was highly supportive and responsive, making the submission process smooth and efficient. The journal's commitment to high standards and academic rigor makes it a respected platform for quality research. I am grateful for the opportunity to publish in such a reputable journal.

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Sonila Qirko

My experience publishing in International Journal of Clinical Case Reports and Reviews was exceptional. I Come forth to Provide a Testimonial Covering the Peer Review Process and the editorial office for the Professional and Impartial Evaluation of the Manuscript.

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Luiz Sellmann

I would like to offer my testimony in the support. I have received through the peer review process and support the editorial office where they are to support young authors like me, encourage them to publish their work in your esteemed journals, and globalize and share knowledge globally. I really appreciate your journal, peer review, and editorial office.

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Zhao Jia

Dear Agrippa Hilda- Editorial Coordinator of Journal of Neuroscience and Neurological Surgery, "The peer review process was very quick and of high quality, which can also be seen in the articles in the journal. The collaboration with the editorial office was very good."

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Thomas Urban

I would like to express my sincere gratitude for the support and efficiency provided by the editorial office throughout the publication process of my article, “Delayed Vulvar Metastases from Rectal Carcinoma: A Case Report.” I greatly appreciate the assistance and guidance I received from your team, which made the entire process smooth and efficient. The peer review process was thorough and constructive, contributing to the overall quality of the final article. I am very grateful for the high level of professionalism and commitment shown by the editorial staff, and I look forward to maintaining a long-term collaboration with the International Journal of Clinical Case Reports and Reviews.

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Cristina Berriozabal

To Dear Erin Aust, I would like to express my heartfelt appreciation for the opportunity to have my work published in this esteemed journal. The entire publication process was smooth and well-organized, and I am extremely satisfied with the final result. The Editorial Team demonstrated the utmost professionalism, providing prompt and insightful feedback throughout the review process. Their clear communication and constructive suggestions were invaluable in enhancing my manuscript, and their meticulous attention to detail and dedication to quality are truly commendable. Additionally, the support from the Editorial Office was exceptional. From the initial submission to the final publication, I was guided through every step of the process with great care and professionalism. The team's responsiveness and assistance made the entire experience both easy and stress-free. I am also deeply impressed by the quality and reputation of the journal. It is an honor to have my research featured in such a respected publication, and I am confident that it will make a meaningful contribution to the field.

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Dr Tewodros Kassahun Tarekegn

"I am grateful for the opportunity of contributing to [International Journal of Clinical Case Reports and Reviews] and for the rigorous review process that enhances the quality of research published in your esteemed journal. I sincerely appreciate the time and effort of your team who have dedicatedly helped me in improvising changes and modifying my manuscript. The insightful comments and constructive feedback provided have been invaluable in refining and strengthening my work".

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Dr Shweta Tiwari

I thank the ‘Journal of Clinical Research and Reports’ for accepting this article for publication. This is a rigorously peer reviewed journal which is on all major global scientific data bases. I note the review process was prompt, thorough and professionally critical. It gave us an insight into a number of important scientific/statistical issues. The review prompted us to review the relevant literature again and look at the limitations of the study. The peer reviewers were open, clear in the instructions and the editorial team was very prompt in their communication. This journal certainly publishes quality research articles. I would recommend the journal for any future publications.

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Dr Farooq Wandroo

Dear Jessica Magne, with gratitude for the joint work. Fast process of receiving and processing the submitted scientific materials in “Clinical Cardiology and Cardiovascular Interventions”. High level of competence of the editors with clear and correct recommendations and ideas for enriching the article.

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Dr Anyuta Ivanova

We found the peer review process quick and positive in its input. The support from the editorial officer has been very agile, always with the intention of improving the article and taking into account our subsequent corrections.

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Dr David Vinyes

My article, titled 'No Way Out of the Smartphone Epidemic Without Considering the Insights of Brain Research,' has been republished in the International Journal of Clinical Case Reports and Reviews. The review process was seamless and professional, with the editors being both friendly and supportive. I am deeply grateful for their efforts.

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Gertraud Teuchert-Noodt

To Dear Erin Aust – Editorial Coordinator of Journal of General Medicine and Clinical Practice! I declare that I am absolutely satisfied with your work carried out with great competence in following the manuscript during the various stages from its receipt, during the revision process to the final acceptance for publication. Thank Prof. Elvira Farina

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Dr Elvira Farina

Dear Jessica, and the super professional team of the ‘Clinical Cardiology and Cardiovascular Interventions’ I am sincerely grateful to the coordinated work of the journal team for the no problem with the submission of my manuscript: “Cardiometabolic Disorders in A Pregnant Woman with Severe Preeclampsia on the Background of Morbid Obesity (Case Report).” The review process by 5 experts was fast, and the comments were professional, which made it more specific and academic, and the process of publication and presentation of the article was excellent. I recommend that my colleagues publish articles in this journal, and I am interested in further scientific cooperation. Sincerely and best wishes, Dr. Oleg Golyanovskiy.

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Dr Oleg Golyanovski

Dear Ashley Rosa, Editorial Coordinator of the journal - Psychology and Mental Health Care. " The process of obtaining publication of my article in the Psychology and Mental Health Journal was positive in all areas. The peer review process resulted in a number of valuable comments, the editorial process was collaborative and timely, and the quality of this journal has been quickly noticed, resulting in alternative journals contacting me to publish with them." Warm regards, Susan Anne Smith, PhD. Australian Breastfeeding Association.

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Dr Susan Anne Smith

Dear Jessica Magne, Editorial Coordinator, Clinical Cardiology and Cardiovascular Interventions, Auctores Publishing LLC. I appreciate the journal (JCCI) editorial office support, the entire team leads were always ready to help, not only on technical front but also on thorough process. Also, I should thank dear reviewers’ attention to detail and creative approach to teach me and bring new insights by their comments. Surely, more discussions and introduction of other hemodynamic devices would provide better prevention and management of shock states. Your efforts and dedication in presenting educational materials in this journal are commendable. Best wishes from, Farahnaz Fallahian.

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Dr Farahnaz Fallahian

Dear Maria Emerson, Editorial Coordinator, International Journal of Clinical Case Reports and Reviews, Auctores Publishing LLC. I am delighted to have published our manuscript, "Acute Colonic Pseudo-Obstruction (ACPO): A rare but serious complication following caesarean section." I want to thank the editorial team, especially Maria Emerson, for their prompt review of the manuscript, quick responses to queries, and overall support. Yours sincerely Dr. Victor Olagundoye.

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Dr Victor Olagundoye

Dear Ashley Rosa, Editorial Coordinator, International Journal of Clinical Case Reports and Reviews. Many thanks for publishing this manuscript after I lost confidence the editors were most helpful, more than other journals Best wishes from, Susan Anne Smith, PhD. Australian Breastfeeding Association.

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Dr Susan Anne Smith

Dear Agrippa Hilda, Editorial Coordinator, Journal of Neuroscience and Neurological Surgery. The entire process including article submission, review, revision, and publication was extremely easy. The journal editor was prompt and helpful, and the reviewers contributed to the quality of the paper. Thank you so much! Eric Nussbaum, MD

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Dr Eric S Nussbaum

Dr Hala Al Shaikh This is to acknowledge that the peer review process for the article ’ A Novel Gnrh1 Gene Mutation in Four Omani Male Siblings, Presentation and Management ’ sent to the International Journal of Clinical Case Reports and Reviews was quick and smooth. The editorial office was prompt with easy communication.

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Hala Al Shaikh

Dear Erin Aust, Editorial Coordinator, Journal of General Medicine and Clinical Practice. We are pleased to share our experience with the “Journal of General Medicine and Clinical Practice”, following the successful publication of our article. The peer review process was thorough and constructive, helping to improve the clarity and quality of the manuscript. We are especially thankful to Ms. Erin Aust, the Editorial Coordinator, for her prompt communication and continuous support throughout the process. Her professionalism ensured a smooth and efficient publication experience. The journal upholds high editorial standards, and we highly recommend it to fellow researchers seeking a credible platform for their work. Best wishes By, Dr. Rakhi Mishra.

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Dr Rakhi Mishra

Dear Jessica Magne, Editorial Coordinator, Clinical Cardiology and Cardiovascular Interventions, Auctores Publishing LLC. The peer review process of the journal of Clinical Cardiology and Cardiovascular Interventions was excellent and fast, as was the support of the editorial office and the quality of the journal. Kind regards Walter F. Riesen Prof. Dr. Dr. h.c. Walter F. Riesen.

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Dr Walter F Riesen

Dear Ashley Rosa, Editorial Coordinator, International Journal of Clinical Case Reports and Reviews, Auctores Publishing LLC. Thank you for publishing our article, Exploring Clozapine's Efficacy in Managing Aggression: A Multiple Single-Case Study in Forensic Psychiatry in the international journal of clinical case reports and reviews. We found the peer review process very professional and efficient. The comments were constructive, and the whole process was efficient. On behalf of the co-authors, I would like to thank you for publishing this article. With regards, Dr. Jelle R. Lettinga.

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Dr Jelle Lettinga

Dear Clarissa Eric, Editorial Coordinator, Journal of Clinical Case Reports and Studies, I would like to express my deep admiration for the exceptional professionalism demonstrated by your journal. I am thoroughly impressed by the speed of the editorial process, the substantive and insightful reviews, and the meticulous preparation of the manuscript for publication. Additionally, I greatly appreciate the courteous and immediate responses from your editorial office to all my inquiries. Best Regards, Dariusz Ziora

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Dariusz Ziora

Dear Chrystine Mejia, Editorial Coordinator, Journal of Neurodegeneration and Neurorehabilitation, Auctores Publishing LLC, We would like to thank the editorial team for the smooth and high-quality communication leading up to the publication of our article in the Journal of Neurodegeneration and Neurorehabilitation. The reviewers have extensive knowledge in the field, and their relevant questions helped to add value to our publication. Kind regards, Dr. Ravi Shrivastava.

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Dr Ravi Shrivastava

Dear Clarissa Eric, Editorial Coordinator, Journal of Clinical Case Reports and Studies, Auctores Publishing LLC, USA Office: +1-(302)-520-2644. I would like to express my sincere appreciation for the efficient and professional handling of my case report by the ‘Journal of Clinical Case Reports and Studies’. The peer review process was not only fast but also highly constructive—the reviewers’ comments were clear, relevant, and greatly helped me improve the quality and clarity of my manuscript. I also received excellent support from the editorial office throughout the process. Communication was smooth and timely, and I felt well guided at every stage, from submission to publication. The overall quality and rigor of the journal are truly commendable. I am pleased to have published my work with Journal of Clinical Case Reports and Studies, and I look forward to future opportunities for collaboration. Sincerely, Aline Tollet, UCLouvain.

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Dr Aline Tollet

Dear Ms. Mayra Duenas, Editorial Coordinator, International Journal of Clinical Case Reports and Reviews. “The International Journal of Clinical Case Reports and Reviews represented the “ideal house” to share with the research community a first experience with the use of the Simeox device for speech rehabilitation. High scientific reputation and attractive website communication were first determinants for the selection of this Journal, and the following submission process exceeded expectations: fast but highly professional peer review, great support by the editorial office, elegant graphic layout. Exactly what a dynamic research team - also composed by allied professionals - needs!" From, Chiara Beccaluva, PT - Italy.

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Dr Chiara Giuseppina Beccaluva

Dear Maria Emerson, Editorial Coordinator, we have deeply appreciated the professionalism demonstrated by the International Journal of Clinical Case Reports and Reviews. The reviewers have extensive knowledge of our field and have been very efficient and fast in supporting the process. I am really looking forward to further collaboration. Thanks. Best regards, Dr. Claudio Ligresti

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Dr Claudio Ligresti

Dear Chrystine Mejia, Editorial Coordinator, Journal of Neurodegeneration and Neurorehabilitation. “The peer review process was efficient and constructive, and the editorial office provided excellent communication and support throughout. The journal ensures scientific rigor and high editorial standards, while also offering a smooth and timely publication process. We sincerely appreciate the work of the editorial team in facilitating the dissemination of innovative approaches such as the Bonori Method.” Best regards, Dr. Matteo Bonori.

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Dr Matteo Bonori

I recommend without hesitation submitting relevant papers on medical decision making to the International Journal of Clinical Case Reports and Reviews. I am very grateful to the editorial staff. Maria Emerson was a pleasure to communicate with. The time from submission to publication was an extremely short 3 weeks. The editorial staff submitted the paper to three reviewers. Two of the reviewers commented positively on the value of publishing the paper. The editorial staff quickly recognized the third reviewer’s comments as an unjust attempt to reject the paper. I revised the paper as recommended by the first two reviewers.

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Edouard Kujawski

Dear Maria Emerson, Editorial Coordinator, Journal of Clinical Research and Reports. Thank you for publishing our case report: "Clinical Case of Effective Fetal Stem Cells Treatment in a Patient with Autism Spectrum Disorder" within the "Journal of Clinical Research and Reports" being submitted by the team of EmCell doctors from Kyiv, Ukraine. We much appreciate a professional and transparent peer-review process from Auctores. All research Doctors are so grateful to your Editorial Office and Auctores Publishing support! I amiably wish our article publication maintained a top quality of your International Scientific Journal. My best wishes for a prosperity of the Journal of Clinical Research and Reports. Hope our scientific relationship and cooperation will remain long lasting. Thank you very much indeed. Kind regards, Dr. Andriy Sinelnyk Cell Therapy Center EmCell

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Dr Andriy Sinelnyk

Dear Editorial Team, Clinical Cardiology and Cardiovascular Interventions. It was truly a rewarding experience to work with the journal “Clinical Cardiology and Cardiovascular Interventions”. The peer review process was insightful and encouraging, helping us refine our work to a higher standard. The editorial office offered exceptional support with prompt and thoughtful communication. I highly value the journal’s role in promoting scientific advancement and am honored to be part of it. Best regards, Meng-Jou Lee, MD, Department of Anesthesiology, National Taiwan University Hospital.

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Dr Meng-JouLe

Dear Editorial Team, Journal-Clinical Cardiology and Cardiovascular Interventions, “Publishing my article with Clinical Cardiology and Cardiovascular Interventions has been a highly positive experience. The peer-review process was rigorous yet supportive, offering valuable feedback that strengthened my work. The editorial team demonstrated exceptional professionalism, prompt communication, and a genuine commitment to maintaining the highest scientific standards. I am very pleased with the publication quality and proud to be associated with such a reputable journal.” Warm regards, Dr. Mahmoud Kamal Moustafa Ahmed

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Mahmoud Kamal Moustafa Ahmed

Dear Maria Emerson, Editorial Coordinator of ‘International Journal of Clinical Case Reports and Reviews’, I appreciate the opportunity to publish my article with your journal. The editorial office provided clear communication during the submission and review process, and I found the overall experience professional and constructive. Best regards, Elena Salvatore.

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Dr Elena Salvatore

Dear Mayra Duenas, Editorial Coordinator of ‘International Journal of Clinical Case Reports and Reviews Herewith I confirm an optimal peer review process and a great support of the editorial office of the present journal

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Christoph Maurer

Dear Editorial Team, Clinical Cardiology and Cardiovascular Interventions. I am really grateful for the peers review; their feedback gave me the opportunity to reflect on the message and impact of my work and to ameliorate the article. The editors did a great job in addition by encouraging me to continue with the process of publishing.

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Baciulescu Laura

Dear Cecilia Lilly, Editorial Coordinator, Endocrinology and Disorders, Thank you so much for your quick response regarding reviewing and all process till publishing our manuscript entitled: Prevalence of Pre-Diabetes and its Associated Risk Factors Among Nile College Students, Sudan. Best regards, Dr Mamoun Magzoub.

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Dr Mamoun Magzoub

International Journal of Clinical Case Reports and Reviews is a high quality journal that has a clear and concise submission process. The peer review process was comprehensive and constructive. Support from the editorial office was excellent, since the administrative staff were responsive. The journal provides a fast and timely publication timeline.

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Joel Yat Seng Wong

Dear Maria Emerson, Editorial Coordinator of International Journal of Clinical Case Reports and Reviews, What distinguishes International Journal of Clinical Case Report and Review is not only the scientific rigor of its publications, but the intellectual climate in which research is evaluated. The submission process is refreshingly free of unnecessary formal barriers and bureaucratic rituals that often complicate academic publishing without adding real value. The peer-review system is demanding yet constructive, guided by genuine scientific dialogue rather than hierarchical or authoritarian attitudes. Reviewers act as collaborators in improving the manuscript, not as gatekeepers imposing arbitrary standards. This journal offers a rare balance: high methodological standards combined with a respectful, transparent, and supportive editorial approach. In an era where publishing can feel more burdensome than research itself, this platform restores the original purpose of peer review — to refine ideas, not to obstruct them Prof. Perlat Kapisyzi, FCCP PULMONOLOGIST AND THORACIC IMAGING.

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Dr Perlat Kapisyzi

Dear Grace Pierce, International Journal of Clinical Case Reports and Reviews I appreciate the opportunity to review for Auctore Journal, as the overall editorial process was smooth, transparent and professionally managed. This journal maintains high scientific standards and ensures timely communications with authors, which is truly commendable. I would like to express my special thanks to editor Grace Pierce for his constant guidance, promt responses, and supportive coordination throughout the review process. I am also greatful to Eleanor Bailey from the finance department for her clear communication and efficient handling of all administrative matters. Overall, my experience with Auctore Journal has been highly positive and rewarding. Best regards, Sabita sinha

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Sabita sinha

Dear Mayra Duenas, Editorial Coordinator of the journal IJCCR, I write here a little on my experience as an author submitting to the International Journal of Clinical Case Reports and Reviews (IJCCR). This was my first submission to IJCCR and my manuscript was inherently an outsider’s effort. It attempted to broadly identify and then make some sense of life’s under-appreciated mysteries. I initially had responded to a request for possible submissions. I then contacted IJCCR with a tentative topic for a manuscript. They quickly got back with an approval for the submission, but with a particular requirement that it be medically relevant. I then put together a manuscript and submitted it. After the usual back-and-forth over forms and formality, the manuscript was sent off for reviews. Within 2 weeks I got back 4 reviews which were both helpful and also surprising. Surprising in that the topic was somewhat foreign to medical literature. My subsequent updates in response to the reviewer comments went smoothly and in short order I had a series of proofs to evaluate. All in all, the whole publication process seemed outstanding. It was both helpful in terms of the paper’s content and also in terms of its efficient and friendly communications. Thank you all very much. Sincerely, Ted Christopher, Rochester, NY.

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Dr Ted Christopher