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Research Article | DOI: https://doi.org/10.31579/2693-4779/300
1Department of Otorhinolaryngology, Head and Neck Surgery, Central Military Hospital, Mexico City, Mexico.
2Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Rey Juan Carlos, Madrid, Spain.
3Department of Surgery, Seoul National University College of Medicine and Hospital, Seoul, Republic of Korea.
4Department of Otorhinolaryngology, Head and Neck Surgery, Regional Military Hospital of Chihuahua, Chihuahua, Mexico.
5Department of Otorhinolaryngology, Head and Neck Surgery, Regional Military Hospital of Acapulco, Acapulco, Mexico.
*Corresponding Author: César Gamaliel Rivera-Martínez, MD, Department of Otorhinolaryngology, Central Military Hospital Periférico Blvrd Manuel Ávila Camacho s/n, Militar, Miguel Hidalgo, 11600 Ciudad de México, CDMX.
Citation: Rivera-Martínez CG, Adelaido L. Chavira, Gabriela R. Arroyo, Jose Granell, Raimundo G. Fonseca, et al, (2025), Robotic Surgery in Otorhinolaryngology-Head and Neck Surgery: a 5-year experience in a Latin American Center, Clinical Research and Clinical Trials, 13(4); DOI:10.31579/2693-4779/300
Copyright: © 2025, César Gamaliel Rivera-Martínez. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Received: 06 October 2025 | Accepted: 16 October 2025 | Published: 30 October 2025
Keywords: transoral robotic surgery; oropharyngeal squamous cell carcinoma; obstructive sleep apnea; robot-assisted thyroidectomy; otolaryngology; carcinoma unknown primary
Background/Aim: To assess the challenges and outcomes of a newly established ORL-HNS robotic program in a Latin American center.
Materials and Methods: A retrospective study evaluating safety, functional, and oncological outcomes of the initial 39 cases of an emerging ORL-HNS robotic program.
Parameters examined in all cases were age, gender, date of surgery, docking and console times, intra and postoperative (PO) complications, abortion or conversion of the procedure, intensive care unit (ICU) stay, and diagnosis.
For patients with oropharyngeal carcinoma, additional data were obtained, including histology, pTNM stage, time to the resumption of oral feeding and decannulation, surgical margins, and adjuvant treatment, 12-month overall survival (OS), and 12-month disease-free survival (DFS) were also obtained. For OSA cases, a paired-samples t-test was used to compare pre- and post-intervention AHI means. Finally, for patients with thyroid pathology, histology, transient and permanent hypocalcemia, transient and permanent laryngeal nerve injury, and aesthetic results were also obtained.
Results: The conversion rate was 2.5% and the complication rate was 7.6%. All patients treated with transoral robotic surgery (TORS) resumed oral feeding in 24 hours, and none required tracheostomy after surgery. The primary tumor was found in 66% of carcinoma unknown primary (CUP) cases after TORS. The 12-month overall survival (OS) was 83.3% for patients with oropharyngeal carcinoma. For patients with obstructive sleep apnea (OSA), there was a statistically significant improvement in apnea-hypopnea index (AHI) values (from 39.1 ± 23.1 events/hour to 20.8 ± 18.9 events/hour) (p = .013). All patients treated with robot-assisted hemithyroidectomy were satisfied with aesthetic results.
Conclusions:
Robot-assisted Surgery (RAS) is feasible and safe. In our experience, it has proven its largest advantage for diagnosing CUP and managing highly selected cases of OSA and OPSCC.
Robot-assisted surgery (RAS) is one of the great medical breakthroughs of the 21st century. RAS has been rapidly adopted in surgical specialties, including urology, gynecology, and general surgery; however, its acceptance in Otolaryngology–Head and Neck Surgery (ORL-HNS) has been more gradual. In 2003, a group at Stanford published a feasibility study of robotic neck surgery in a porcine model [1]. In 2005, a supraglottic partial laryngectomy in a canine model was the first live application of transoral robotic surgery (TORS) [2]. That same year, McLeod and Melder performed the first robotic procedure on a human patient with the resection of a vallecular cyst [3]. In 2007, Weinstein and O’Malley published a prospective series of 27 patients treated with radical tonsillectomy for oropharyngeal squamous cell carcinoma (OPSCC) [4]. In 2009, the first series of robot-assisted thyroidectomies was published [5]. Later that year, the United States Food and Drug Administration (FDA) approved TORS for T1-T2 OPSCC. In 2010, TORS was used for the management of OSA by Vicini et al. [6]. Other indications for RAS, such as parathyroidectomy, neck dissection, laryngectomy, and diagnostic mucosectomy of carcinoma of unknown primary (CUP), have also been described. There are nearly 130 robotic surgery programs in Latin America, 20 of which are in Mexico. There are few published studies on RAS in Mexico [7-10], and to our knowledge, none include ORL-HNS cases. Introducing RAS into clinical practice is challenging, as it is a costly health infrastructure that depends strongly on having adequately trained medical professionals. A standardized model for implementing a robotic ORL-HNS clinical program in developing nations has not been described. This study aims to present the experience of establishing an ORL-HNS robotic surgery program in an academic center and to assess the outcomes of the procedures undertaken since its inception.
Materials and Methods
This series comprises all ORL-HNS patients managed with robot-assisted surgery from April 2017 to August 2023 at a publicly funded tertiary care facility in Mexico City. Each case was discussed with the hospital's robotic surgery committee for authorization, and carcinoma cases were also discussed at the tumor board meeting. Written informed consent was obtained from all patients.
Surgical Technique
The da Vinci Surgical Robot, Si version (Intuitive Surgical, Sunnyvale, California, USA) was used for all procedures. All patients were under general anesthesia and all TORS cases were done with nasotracheal intubation. The setup for TORS cases included three robotic arms: a robotic 0°, 8.5 mm camera was placed in the central arm, a 5 mm monopolar cautery was placed in the arm ipsilateral to the tumor, and a 5 mm Endowrist Maryland Forceps was placed in the contralateral robotic arm. Transoral exposure was obtained with either a Davis Boyle or a Davis Meyer retractor. For patients requiring neck dissection, it was performed by an open approach at a different surgical time. Robot-assisted thyroid procedures were performed with orotracheal intubation and laryngeal nerve monitoring with a bilateral axillary-breast approach (BABA). The setup included a robotic 30° 12 mm downward-facing camera positioned in the right breast incision, and an 8 mm hook monopolar cautery was inserted through the left breast incision, which was exchanged with Harmonic Ace Curved Shears as needed. An 8 mm Endowrist Maryland Forceps and an 8 mm Prograsp Endowrist Forceps 8mm were inserted through the axillary incisions.
Variables
All charts were reviewed to obtain the following data: age, gender, date of surgery, docking and console times, intra and postoperative (PO) complications, abortion or conversion of the procedure, intensive care unit (ICU) stay, and diagnosis [7]. Complications were categorized using the Clavien-Dindo (CD) classification [11].
For patients with a diagnosis of oropharyngeal carcinoma, specific additional data were obtained: tumor subsite, histology, pTNM stage, p16 status, whether or not tracheotomy was performed, insertion of a nasogastric tube or gastrostomy, time to the resumption of oral feeding and decannulation, surgical margins, and adjuvant treatment. Recurrence, 12-month overall survival (OS), and 12-month disease-free survival (DFS) were also obtained [12]. The specific variables obtained for OSA cases were the volume resected and pre-operative and postoperative AHI values. Surgical success was defined as a >50% reduction of AHI and a postoperative AHI < 20>
Statical Analysis
The normality of the distribution for both pre- and post-intervention AHI scores was assessed using the Shapiro–Wilk test. Given that both distributions did not significantly deviate from normality, parametric analyses were performed. A paired-samples t-test was used to compare pre- and post-intervention AHI means. The magnitude of the effect was quantified using Cohen’s d for the t-test, with conventional thresholds of .2, .5, and .8 (for d) interpreted as small, medium, and large effects, respectively.
Statistical significance was set at p < .05. Statistical analyses were performed using SPSS 26.0 for Windows (SPSS, Chicago, IL).
A total of 39 procedures were done. Details of the patients treated are summarized in Table 1. The first procedure done was the resection of a vallecular cyst. Two more cases of benign lesions were performed in 2017 and 2018, but then TORS was limited to OSA and cases involving malignant pathology. The number of robot-assisted surgery thyroid procedures diminished over time. The conversion rate was 2.5%, and the complication rate was 7.6%. The ICU stay was minimal, indicated only in an 84-year patient for monitoring. All patients treated with TORS restarted oral diet in the first 24 hours after surgery, and no patient required a tracheostomy after the intervention.
Table 1: Patients’ characteristics treated with robotic surgery
ICU, Intensive Care Unit; OSA, Obstructive sleep apnea; TORS, Transoral robot-assisted surgery; RAS, Robot-assisted surgery; CD, Clavien Dindo.
TORS for management of malignant pathology
Of the 14 patients with carcinoma, 11 were diagnosed with oropharyngeal carcinoma, and three had CUP.
The primary tumor was found after TORS in two of the three CUP cases. One of these CUP patients was diagnosed with OPSCC T1N1M0. The other was diagnosed with hypopharyngeal squamous cell carcinoma during surgical exploration, which was deemed non-resectable, a biopsy was performed and the patient received chemoradiotherapy.
Table 2 summarises the management and follow-up of the 12 patients with oropharyngeal carcinoma. The 12-month OS and 12-month DFS were 83.3% in both cases. Recurrence was distant in all cases, with no case presenting locoregional recurrence.
Table 2: Characteristics, management and follow-up of Patients Diagnosed with Oropharyngeal Carcinoma
*The tumor board advised PO CRT; yet, before treatment was delivered the patient lost follow-up due to COVID-19 disease, and treatment was delayed.
SCC, Squamous cell carcinoma; BOT, base of tongue; NA, not available; CRT, Chemoradiotherapy; CT, chemotherapy; PORT, Postoperative radiotherapy
None of the patients with oropharyngeal carcinoma required a tracheotomy or gastrostomy during follow-up. Some patients complained of mild and transitory dysphagia during follow-up, yet all of them managed a full oral feeding. Hence, no further evaluation was performed.
Obstructive Sleep Apnea (OSA)
Five patients (35.7%) had undergone previous surgery. Base of tongue management was performed in all cases with resection of a median volume of 6 cc. In three cases (21.4%), a partial epiglottectomy was performed simultaneously. There was a statistically significant improvement in AHI values (from 39.1 ± 23.1 events/hour to 20.8 ± 18.9 events/hour) (p = .013). Cohen’s d = 0.77, denoting a medium-to-large effect size.
Surgical cure was achieved in 4 patients (28.5%), surgical success in 4 patients (28.5%), PO AHI improved without reaching surgical success in 2 patients (14.2%), PO AHI had minimal changes in 2 patients (14.2%), and PO AHI worsened in 2 patients (14.2%). Two patients (14.2%) presented PO bleeding and only one required surgical management. The remaining patients did not present PO complications.
Robot-assisted Thyroid Surgery
Of all the patients treated surgically for thyroid pathology at our ORL-HNS Department, only 0.7% were robot-assisted. Eight patients were programmed for robot-assisted surgery. Robot-assisted hemithyroidectomy was performed successfully in seven patients; in the remaining patient, who
had a T3bN0M0 papillary carcinoma, the procedure was converted. Of the patients that had robot-assisted hemithyroidectomy, six had benign histology, and one was classified as T2N0M0 papillary carcinoma; the patient underwent an open complementary hemithyroidectomy. Vocal cord function was normal in all patients. No patients had transient or permanent hypocalcemia. All the patients treated entirely by robot-assisted surgery were satisfied with the functional and aesthetic results.
The conversion and complication rates are comparable to previous studies. The most prevalent complication was PO bleeding [12]. Oral intake was resumed earlier, and tracheostomy and gastrostomy rates are lower than in series treating patients with OPSCC [14-16]. This represents a reduction in short-term morbidity without affecting safety, which is one of the reasons to advocate in favor of robotic surgery. Console time was longer in our series compared to that reported by high-volume centers [17]; yet, there were anesthetic complications related to longer surgical times. On the other hand, this is likely to reduce as the team gathers more experience.
For oropharyngeal carcinoma, the achievement of negative surgical margins was comparable to previous series [18]. Nevertheless, the 12-month OS rate was slightly poorer than the series that only included OPSCC cases [19]. However, it must be considered that in our small series, one of the patients had mucoepidermoid carcinoma, and the other had a T3N3bM0 p16 negative, sarcomatoid variant of oropharyngeal carcinoma; both tumors have aggressive behavior. If only early-stage OPSCC patients were considered, OS would be 100% comparable to other series.
The evaluation of functional outcomes has been oversimplified, and an appropriate objective evaluation of dysphagia and patient-reported outcome measures should be obtained in the future. In cases of OPSCC, a comparison of oncological and functional results of patients treated with TORS with or without adjuvant treatment compared to definite radiotherapy or chemoradiotherapy in the future is also needed. The role of TORS in de-escalation protocols in patients with p16-positive tumors is also an interesting area of future research.
Base of tongue reduction using TORS significantly decreases AHI. Overall, the AHI reduction obtained in this series (39.1 ± 23.1 to 20.8 ± 18.9 events/hour) is slightly lower compared to results (44.3 ± 22.4 to 17.8 ± 16.5 events/hour) reported in the systematic review published by Miller et al [20]. Nevertheless, the surgical cure in this series (28.5%) was slightly higher than that obtained in the same systematic review (23.8%); these differences could be explained by the fact that in the latter, TORS was part of multilevel surgery in 83.9% of patients, who also had more severe OSA. This observation supports that TORS is merely a tool and not the sole solution for managing OSA, and surgical decision-making is highly individualized.
About 2% of patients with surgical thyroid pathology evaluated in the service during this period were eligible for robot-assisted thyroidectomy because most patients present with locally advanced disease. Most patients who were offered robot-assisted thyroidectomy declined the procedure and opted for open surgery. The patient's preference likely reflects cultural differences with nations that popularised the technique, such as South Korea. Considering that the most significant advantage of remote access thyroidectomy is the cosmetic result [21] and the low interest of patients in avoiding a visible scar, other robotic neck procedures such as neck dissection and parotidectomy have not yet been introduced in our department.
We recognize this study's limitations, which include the retrospective nature of the data, the relatively small number of patients included, and the heterogeneity of procedures performed.
As described by Secin et al., the development of robotic surgery in Latin America has been slow, and programs are fragile and threatened by affordability [22]. On the other hand, patients with appropriate indications for robot-assisted surgery in ORL-HNS in our setting are still scarce, as most of the patients with OPSCC are diagnosed with locally advanced disease, with thyroid nodules larger than 4 cm, and patients with OSA most times do not meet surgical indications. Furthermore, appropriate certification can only be obtained abroad which adds complexity to successfully overcoming the learning curve. The small number of patients, also hinders the development of well-designed clinical trials able to answer the lingering questions on the role of robotic surgery in ORL-HNS.
Despite the limitations mentioned, this exploratory study is useful for establishing precedent regarding the use of robotic surgery in the ORL-HNS Latin American Department. It is valuable for designing future studies with less methodological bias. It also makes evident that Latin American academic centers should incorporate robotic surgery in their programs, because as a region, we are already falling behind. As clinicians are more familiar with indications of robotic surgery and the infrastructure is more widely available, most of the challenges faced in this initial experience, will fade. On the other hand, the research field in robotic surgery is far from ending as many interesting questions remain unanswered.
Robot-assisted surgery has numerous applications and advantages for patients with ORL-NHS pathology, and it is slowly becoming standard practice worldwide. Academic third-level centers in Latin America should introduce robotic ORL-HNS programs. Although a wide variety of ORL-HNS procedures can be performed safely and with good results, in our experience, robot-assisted surgery has proven its strongest advantage in diagnosing CUP and managing highly selected cases of OSA and OPSCC. Further studies are required to investigate which patients will obtain a significant advantage in quality of life when treated with robot-assisted surgery compared to traditional treatment, despite the high costs of this technology.
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I would like to express my sincere gratitude for the support and efficiency provided by the editorial office throughout the publication process of my article, “Delayed Vulvar Metastases from Rectal Carcinoma: A Case Report.” I greatly appreciate the assistance and guidance I received from your team, which made the entire process smooth and efficient. The peer review process was thorough and constructive, contributing to the overall quality of the final article. I am very grateful for the high level of professionalism and commitment shown by the editorial staff, and I look forward to maintaining a long-term collaboration with the International Journal of Clinical Case Reports and Reviews.
To Dear Erin Aust, I would like to express my heartfelt appreciation for the opportunity to have my work published in this esteemed journal. The entire publication process was smooth and well-organized, and I am extremely satisfied with the final result. The Editorial Team demonstrated the utmost professionalism, providing prompt and insightful feedback throughout the review process. Their clear communication and constructive suggestions were invaluable in enhancing my manuscript, and their meticulous attention to detail and dedication to quality are truly commendable. Additionally, the support from the Editorial Office was exceptional. From the initial submission to the final publication, I was guided through every step of the process with great care and professionalism. The team's responsiveness and assistance made the entire experience both easy and stress-free. I am also deeply impressed by the quality and reputation of the journal. It is an honor to have my research featured in such a respected publication, and I am confident that it will make a meaningful contribution to the field.
"I am grateful for the opportunity of contributing to [International Journal of Clinical Case Reports and Reviews] and for the rigorous review process that enhances the quality of research published in your esteemed journal. I sincerely appreciate the time and effort of your team who have dedicatedly helped me in improvising changes and modifying my manuscript. The insightful comments and constructive feedback provided have been invaluable in refining and strengthening my work".
I thank the ‘Journal of Clinical Research and Reports’ for accepting this article for publication. This is a rigorously peer reviewed journal which is on all major global scientific data bases. I note the review process was prompt, thorough and professionally critical. It gave us an insight into a number of important scientific/statistical issues. The review prompted us to review the relevant literature again and look at the limitations of the study. The peer reviewers were open, clear in the instructions and the editorial team was very prompt in their communication. This journal certainly publishes quality research articles. I would recommend the journal for any future publications.
Dear Jessica Magne, with gratitude for the joint work. Fast process of receiving and processing the submitted scientific materials in “Clinical Cardiology and Cardiovascular Interventions”. High level of competence of the editors with clear and correct recommendations and ideas for enriching the article.
We found the peer review process quick and positive in its input. The support from the editorial officer has been very agile, always with the intention of improving the article and taking into account our subsequent corrections.
My article, titled 'No Way Out of the Smartphone Epidemic Without Considering the Insights of Brain Research,' has been republished in the International Journal of Clinical Case Reports and Reviews. The review process was seamless and professional, with the editors being both friendly and supportive. I am deeply grateful for their efforts.
To Dear Erin Aust – Editorial Coordinator of Journal of General Medicine and Clinical Practice! I declare that I am absolutely satisfied with your work carried out with great competence in following the manuscript during the various stages from its receipt, during the revision process to the final acceptance for publication. Thank Prof. Elvira Farina
Dear Jessica, and the super professional team of the ‘Clinical Cardiology and Cardiovascular Interventions’ I am sincerely grateful to the coordinated work of the journal team for the no problem with the submission of my manuscript: “Cardiometabolic Disorders in A Pregnant Woman with Severe Preeclampsia on the Background of Morbid Obesity (Case Report).” The review process by 5 experts was fast, and the comments were professional, which made it more specific and academic, and the process of publication and presentation of the article was excellent. I recommend that my colleagues publish articles in this journal, and I am interested in further scientific cooperation. Sincerely and best wishes, Dr. Oleg Golyanovskiy.
Dear Ashley Rosa, Editorial Coordinator of the journal - Psychology and Mental Health Care. " The process of obtaining publication of my article in the Psychology and Mental Health Journal was positive in all areas. The peer review process resulted in a number of valuable comments, the editorial process was collaborative and timely, and the quality of this journal has been quickly noticed, resulting in alternative journals contacting me to publish with them." Warm regards, Susan Anne Smith, PhD. Australian Breastfeeding Association.
Dear Jessica Magne, Editorial Coordinator, Clinical Cardiology and Cardiovascular Interventions, Auctores Publishing LLC. I appreciate the journal (JCCI) editorial office support, the entire team leads were always ready to help, not only on technical front but also on thorough process. Also, I should thank dear reviewers’ attention to detail and creative approach to teach me and bring new insights by their comments. Surely, more discussions and introduction of other hemodynamic devices would provide better prevention and management of shock states. Your efforts and dedication in presenting educational materials in this journal are commendable. Best wishes from, Farahnaz Fallahian.
Dear Maria Emerson, Editorial Coordinator, International Journal of Clinical Case Reports and Reviews, Auctores Publishing LLC. I am delighted to have published our manuscript, "Acute Colonic Pseudo-Obstruction (ACPO): A rare but serious complication following caesarean section." I want to thank the editorial team, especially Maria Emerson, for their prompt review of the manuscript, quick responses to queries, and overall support. Yours sincerely Dr. Victor Olagundoye.
Dear Ashley Rosa, Editorial Coordinator, International Journal of Clinical Case Reports and Reviews. Many thanks for publishing this manuscript after I lost confidence the editors were most helpful, more than other journals Best wishes from, Susan Anne Smith, PhD. Australian Breastfeeding Association.
Dear Agrippa Hilda, Editorial Coordinator, Journal of Neuroscience and Neurological Surgery. The entire process including article submission, review, revision, and publication was extremely easy. The journal editor was prompt and helpful, and the reviewers contributed to the quality of the paper. Thank you so much! Eric Nussbaum, MD
Dr Hala Al Shaikh This is to acknowledge that the peer review process for the article ’ A Novel Gnrh1 Gene Mutation in Four Omani Male Siblings, Presentation and Management ’ sent to the International Journal of Clinical Case Reports and Reviews was quick and smooth. The editorial office was prompt with easy communication.
Dear Erin Aust, Editorial Coordinator, Journal of General Medicine and Clinical Practice. We are pleased to share our experience with the “Journal of General Medicine and Clinical Practice”, following the successful publication of our article. The peer review process was thorough and constructive, helping to improve the clarity and quality of the manuscript. We are especially thankful to Ms. Erin Aust, the Editorial Coordinator, for her prompt communication and continuous support throughout the process. Her professionalism ensured a smooth and efficient publication experience. The journal upholds high editorial standards, and we highly recommend it to fellow researchers seeking a credible platform for their work. Best wishes By, Dr. Rakhi Mishra.
Dear Jessica Magne, Editorial Coordinator, Clinical Cardiology and Cardiovascular Interventions, Auctores Publishing LLC. The peer review process of the journal of Clinical Cardiology and Cardiovascular Interventions was excellent and fast, as was the support of the editorial office and the quality of the journal. Kind regards Walter F. Riesen Prof. Dr. Dr. h.c. Walter F. Riesen.
Dear Ashley Rosa, Editorial Coordinator, International Journal of Clinical Case Reports and Reviews, Auctores Publishing LLC. Thank you for publishing our article, Exploring Clozapine's Efficacy in Managing Aggression: A Multiple Single-Case Study in Forensic Psychiatry in the international journal of clinical case reports and reviews. We found the peer review process very professional and efficient. The comments were constructive, and the whole process was efficient. On behalf of the co-authors, I would like to thank you for publishing this article. With regards, Dr. Jelle R. Lettinga.
Dear Clarissa Eric, Editorial Coordinator, Journal of Clinical Case Reports and Studies, I would like to express my deep admiration for the exceptional professionalism demonstrated by your journal. I am thoroughly impressed by the speed of the editorial process, the substantive and insightful reviews, and the meticulous preparation of the manuscript for publication. Additionally, I greatly appreciate the courteous and immediate responses from your editorial office to all my inquiries. Best Regards, Dariusz Ziora
Dear Chrystine Mejia, Editorial Coordinator, Journal of Neurodegeneration and Neurorehabilitation, Auctores Publishing LLC, We would like to thank the editorial team for the smooth and high-quality communication leading up to the publication of our article in the Journal of Neurodegeneration and Neurorehabilitation. The reviewers have extensive knowledge in the field, and their relevant questions helped to add value to our publication. Kind regards, Dr. Ravi Shrivastava.
Dear Clarissa Eric, Editorial Coordinator, Journal of Clinical Case Reports and Studies, Auctores Publishing LLC, USA Office: +1-(302)-520-2644. I would like to express my sincere appreciation for the efficient and professional handling of my case report by the ‘Journal of Clinical Case Reports and Studies’. The peer review process was not only fast but also highly constructive—the reviewers’ comments were clear, relevant, and greatly helped me improve the quality and clarity of my manuscript. I also received excellent support from the editorial office throughout the process. Communication was smooth and timely, and I felt well guided at every stage, from submission to publication. The overall quality and rigor of the journal are truly commendable. I am pleased to have published my work with Journal of Clinical Case Reports and Studies, and I look forward to future opportunities for collaboration. Sincerely, Aline Tollet, UCLouvain.
Dear Ms. Mayra Duenas, Editorial Coordinator, International Journal of Clinical Case Reports and Reviews. “The International Journal of Clinical Case Reports and Reviews represented the “ideal house” to share with the research community a first experience with the use of the Simeox device for speech rehabilitation. High scientific reputation and attractive website communication were first determinants for the selection of this Journal, and the following submission process exceeded expectations: fast but highly professional peer review, great support by the editorial office, elegant graphic layout. Exactly what a dynamic research team - also composed by allied professionals - needs!" From, Chiara Beccaluva, PT - Italy.
Dear Maria Emerson, Editorial Coordinator, we have deeply appreciated the professionalism demonstrated by the International Journal of Clinical Case Reports and Reviews. The reviewers have extensive knowledge of our field and have been very efficient and fast in supporting the process. I am really looking forward to further collaboration. Thanks. Best regards, Dr. Claudio Ligresti
Dear Chrystine Mejia, Editorial Coordinator, Journal of Neurodegeneration and Neurorehabilitation. “The peer review process was efficient and constructive, and the editorial office provided excellent communication and support throughout. The journal ensures scientific rigor and high editorial standards, while also offering a smooth and timely publication process. We sincerely appreciate the work of the editorial team in facilitating the dissemination of innovative approaches such as the Bonori Method.” Best regards, Dr. Matteo Bonori.
I recommend without hesitation submitting relevant papers on medical decision making to the International Journal of Clinical Case Reports and Reviews. I am very grateful to the editorial staff. Maria Emerson was a pleasure to communicate with. The time from submission to publication was an extremely short 3 weeks. The editorial staff submitted the paper to three reviewers. Two of the reviewers commented positively on the value of publishing the paper. The editorial staff quickly recognized the third reviewer’s comments as an unjust attempt to reject the paper. I revised the paper as recommended by the first two reviewers.
Dear Maria Emerson, Editorial Coordinator, Journal of Clinical Research and Reports. Thank you for publishing our case report: "Clinical Case of Effective Fetal Stem Cells Treatment in a Patient with Autism Spectrum Disorder" within the "Journal of Clinical Research and Reports" being submitted by the team of EmCell doctors from Kyiv, Ukraine. We much appreciate a professional and transparent peer-review process from Auctores. All research Doctors are so grateful to your Editorial Office and Auctores Publishing support! I amiably wish our article publication maintained a top quality of your International Scientific Journal. My best wishes for a prosperity of the Journal of Clinical Research and Reports. Hope our scientific relationship and cooperation will remain long lasting. Thank you very much indeed. Kind regards, Dr. Andriy Sinelnyk Cell Therapy Center EmCell
Dear Editorial Team, Clinical Cardiology and Cardiovascular Interventions. It was truly a rewarding experience to work with the journal “Clinical Cardiology and Cardiovascular Interventions”. The peer review process was insightful and encouraging, helping us refine our work to a higher standard. The editorial office offered exceptional support with prompt and thoughtful communication. I highly value the journal’s role in promoting scientific advancement and am honored to be part of it. Best regards, Meng-Jou Lee, MD, Department of Anesthesiology, National Taiwan University Hospital.
Dear Editorial Team, Journal-Clinical Cardiology and Cardiovascular Interventions, “Publishing my article with Clinical Cardiology and Cardiovascular Interventions has been a highly positive experience. The peer-review process was rigorous yet supportive, offering valuable feedback that strengthened my work. The editorial team demonstrated exceptional professionalism, prompt communication, and a genuine commitment to maintaining the highest scientific standards. I am very pleased with the publication quality and proud to be associated with such a reputable journal.” Warm regards, Dr. Mahmoud Kamal Moustafa Ahmed
Dear Maria Emerson, Editorial Coordinator of ‘International Journal of Clinical Case Reports and Reviews’, I appreciate the opportunity to publish my article with your journal. The editorial office provided clear communication during the submission and review process, and I found the overall experience professional and constructive. Best regards, Elena Salvatore.
Dear Mayra Duenas, Editorial Coordinator of ‘International Journal of Clinical Case Reports and Reviews Herewith I confirm an optimal peer review process and a great support of the editorial office of the present journal
Dear Editorial Team, Clinical Cardiology and Cardiovascular Interventions. I am really grateful for the peers review; their feedback gave me the opportunity to reflect on the message and impact of my work and to ameliorate the article. The editors did a great job in addition by encouraging me to continue with the process of publishing.
Dear Cecilia Lilly, Editorial Coordinator, Endocrinology and Disorders, Thank you so much for your quick response regarding reviewing and all process till publishing our manuscript entitled: Prevalence of Pre-Diabetes and its Associated Risk Factors Among Nile College Students, Sudan. Best regards, Dr Mamoun Magzoub.
International Journal of Clinical Case Reports and Reviews is a high quality journal that has a clear and concise submission process. The peer review process was comprehensive and constructive. Support from the editorial office was excellent, since the administrative staff were responsive. The journal provides a fast and timely publication timeline.
Dear Maria Emerson, Editorial Coordinator of International Journal of Clinical Case Reports and Reviews, What distinguishes International Journal of Clinical Case Report and Review is not only the scientific rigor of its publications, but the intellectual climate in which research is evaluated. The submission process is refreshingly free of unnecessary formal barriers and bureaucratic rituals that often complicate academic publishing without adding real value. The peer-review system is demanding yet constructive, guided by genuine scientific dialogue rather than hierarchical or authoritarian attitudes. Reviewers act as collaborators in improving the manuscript, not as gatekeepers imposing arbitrary standards. This journal offers a rare balance: high methodological standards combined with a respectful, transparent, and supportive editorial approach. In an era where publishing can feel more burdensome than research itself, this platform restores the original purpose of peer review — to refine ideas, not to obstruct them Prof. Perlat Kapisyzi, FCCP PULMONOLOGIST AND THORACIC IMAGING.
Dear Grace Pierce, International Journal of Clinical Case Reports and Reviews I appreciate the opportunity to review for Auctore Journal, as the overall editorial process was smooth, transparent and professionally managed. This journal maintains high scientific standards and ensures timely communications with authors, which is truly commendable. I would like to express my special thanks to editor Grace Pierce for his constant guidance, promt responses, and supportive coordination throughout the review process. I am also greatful to Eleanor Bailey from the finance department for her clear communication and efficient handling of all administrative matters. Overall, my experience with Auctore Journal has been highly positive and rewarding. Best regards, Sabita sinha
Dear Mayra Duenas, Editorial Coordinator of the journal IJCCR, I write here a little on my experience as an author submitting to the International Journal of Clinical Case Reports and Reviews (IJCCR). This was my first submission to IJCCR and my manuscript was inherently an outsider’s effort. It attempted to broadly identify and then make some sense of life’s under-appreciated mysteries. I initially had responded to a request for possible submissions. I then contacted IJCCR with a tentative topic for a manuscript. They quickly got back with an approval for the submission, but with a particular requirement that it be medically relevant. I then put together a manuscript and submitted it. After the usual back-and-forth over forms and formality, the manuscript was sent off for reviews. Within 2 weeks I got back 4 reviews which were both helpful and also surprising. Surprising in that the topic was somewhat foreign to medical literature. My subsequent updates in response to the reviewer comments went smoothly and in short order I had a series of proofs to evaluate. All in all, the whole publication process seemed outstanding. It was both helpful in terms of the paper’s content and also in terms of its efficient and friendly communications. Thank you all very much. Sincerely, Ted Christopher, Rochester, NY.
