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case report | DOI: https://doi.org/10.31579/2693-2156/151
Critical Care Unit, Kafr El-Bateekh Central Hospital, Egyptian Ministry of Health (MOH), Damietta, Egypt
*Corresponding Author: Yasser Mohammed Hassanain Elsayed, Critical Care Unit, Kafr El-Bateekh Central Hospital, Egyptian Ministry of Health (MOH), Damietta, Egypt
Citation: Yasser Mohammed Hassanain Elsayed*, (2025), Yasser's Squaring Saddling Syndrome, Partial Modified Yasser's WPW Syndrome, Yasser's Lateral Halo Sign, Neglected Infarction, Bifasicular Block, and Craniofacial Hyperhidrosis Post-Organophosphorus with Interlacing COVID-Pneumonia-Cardiovascular-Radiological Discoveries, Journal of Thoracic Disease and Cardiothoracic Surgery; 6(6): DOI: 10.31579/2693-2156/151
Copyright: © 2025 Yasser Mohammed Hassanain Elsayed, this is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited
Received: 01 December 2025 | Accepted: 12 December 2025 | Published: 22 December 2025
Keywords: yasser's squaring saddling syndrome, partial modified yasser's wpw syndrome, yasser's lateral halo sign, silent infarction, heart block, craniofacial hyperhidrosis, organophosphorus, covid-pneumonia
Introduction: `Hyperhidrosis (HH) is described as overrun sweating that directly influences the quality of life, emotional, social, and professional status of the patient. Silent myocardial ischemia is an ischemic episode without causing noticeable symptoms like chest pain or discomfort, with at least 15% to 30% of acute myocardial infarction have evidence of prior silent myocardial ischemia. Right bundle branch block (RBBB) alternating with either left anterior fascicular block (LAFB) or left posterior fascicular block (LPFB) results in a bifascicular block in the ECG. Organophosphates (OP) are a diverse group of chemical compounds that have cardiovascular, neurological, and respiratory adverse effects. Kounis-Zafras (KZ) syndrome is a newly described syndrome relevant to allergen exposure. COVID-19 infection may have lethal cardiovascular and respiratory complications. The halo sign and the reversed halo sign in CT are associated with patches of ground-glass opacities at the late phase of COVID-19 infection. Case presentation: Elderly married male, a Farmer, a non-smoker, Egyptian, patient, was presented to the POC after over 5 years of follow-up, after two attacks of COVID-19 pneumonia and a neglected and passed myocardial infarction, post-prolonged exposure history of inhalation of organophosphorus. The chest CT, oxygenation, ECG, and echocardiographywere the interventions. Conclusion: "Yasser's squaring saddling syndrome", "partial modified Yasser's WPW syndrome", and "Yasser's lateral halo sign" are new cardiovascular and radiological discoveries. Senility, chronic exposure to organophosphates, old myocardial infarction, two attacks of COVID-19 pneumonia, fixed bifasicular heart block, transient trifasicular heart block, dilated cardiomyopathy, bigeminal premature ventricular complexes (PVCs), multiple irregular PVCs, premature ventricular couplets, runs of ventricular tachycardia (VT), and left ventricular (LV) systolic dysfunction with global hypokinesia are serious constellation risk factors. Further wide studies will be recommended.
ACS: Acute coronary syndrome
AMI: Acute myocardial infarction
CAS: Coronary artery spasm
CBC: Complete blood count
COVID-19: Coronavirus disease 2019
ECG: Electrocardiography
HH: Hyperhidrosis
IHD: Ischemic heart disease
ICU: Intensive care unit
KZ; Kounis Zafras
LAFB: Left anterior fascicular block
LPFB: Left posterior fascicular block
OP: Organophosphates
PVC: Premature ventricular complex
RBBB: Right bundle branch block
VR: Ventricular rate
VT: Ventricular tachycardia
WPW syndrome: Wolff-Parkinson-White syndrome
Hyperhidrosis (HH) is described as an overproduction of sweat beyond the physiological necessary amount, which meets the body’s thermal regulation. It is mostly regional due to hyperfunctioning of the sweat gland. Unfortunately, it is directly influencing the quality of life, emotional, social, and professional aspects of the patient. HH is either primary or secondary [1]. Primary HH is often bilateral, symmetrical, improves during sleep, and worsens in situations of stress conditions with no detected cause. It may be genetic and familial. Hyperthyroidism, hyperpituitarism, diabetes mellitus, menopause, pregnancy, pheochromocytoma, carcinoid syndrome, acromegaly, Parkinson's disease, spinal cord injury, stroke, Hodgkin's disease, myeloproliferative diseases, tuberculosis, septicemia, fluoxetine, venlafaxine, doxepin, alcoholism, substance abuse, [2] and Frey’s syndrome due to parotid surgery [3] are implicated as a secondary HH. Surgical treatment of craniofacial sweating is more likely to be followed by undesirable side effects [4]. Treatment of the underlying cause is the choice for secondary hyperhidrosis [2]. Organophosphates (OP) encompass a diverse group of chemical compounds with common applications in pesticides and herbicides that inhibit acetylcholinesterase (AChE) enzyme, resulting in an oversecretion of acetylcholine [5]. According to the WHO, in 1990 estimated that there were 1 million unintentional pesticide poisonings, resulting in approximately 20,000 fatalities [6]. Consequences of hypovolemia or hypoxia, peripheral vasodilatation, and direct myocardial damage may be present with OP poisoning. Muscarinic cardiovascular effects due to muscarinic receptor stimulation result in bradycardia, conduction block, and hypotension by parasympathetic overactivity, whereas nicotinic cardiovascular signs of AChE inhibitor toxicity due to nicotinic receptor stimulation result in hypertension and tachycardia by sympathetic overactivity [5,7]. The electrophysiological abnormalities often include ventricular tachyarrhythmias, torsades de pointes, QT interval prolongation, ST-segment deviations, tall T waves, premature contractions, and AVB [7]. Silent myocardial ischemia refers to a condition where myocardial blood flow is reduced without causing noticeable symptoms such as chest pain or discomfort. At least 15% to 30% of patients with acute myocardial infarction have evidence of prior silent myocardial ischemia. Older patients, diabetes mellitus, obstructive sleep apnea, critically ill patients, and perioperative situations are risk factors that increase susceptibility to asymptomatic ischemic episodes [8]. Interruptions in conduction may occur with right bundle branch block (RBBB) alternating with either left anterior fascicular block (LAFB) or left posterior fascicular block (LPFB), producing bifascicular block in the ECG [9]. Wolff-Parkinson-White (WPW) syndrome is a cardiac preexcitation syndrome that arises from an abnormal accessory pathway that can result in symptomatic and life-threatening arrhythmias. It hallmarks the ECG of a short PR interval, wide QRS, and delta wave in the presence of sinus rhythm [10]. Allergic acute coronary syndrome or KZ syndrome is hallmarked by the co-association of an ACS with hypersensitivity reactions following an allergenic exposure [11]. KS was initially identified by Kounis and Zavras in 1991 as an “allergic angina syndrome”, “allergic angina” or “allergic myocardial infarction” [11,12]. There is ACS-associated mast cell activation from allergic, hypersensitivity, or anaphylactoid reactions [12]. The essential pathogenesis of KS is the inflammatory cytokines mediators released through mast cell activation during a hypersensitivity reaction triggered by food, insect bites, or drugs. There is a subsequent coronary artery spasm (CAS) with possible atheromatous plaque erosion or rupture [12]. The allergic angina commonly starts within one hour of exposure to the offending allergen. Longer onset of ACS has also been reported [13]. Variant presentations of KS have been reported [12]. Three different variants of KS have been described: Type I occurs in structurally normal coronary arteries with no cardiovascular risk factors. The coronary spasm was suggested. With or without an associated acute myocardial infarction (AMI). Type II KS occurs in patients with pre-existing ischemic heart disease (IHD), in whom the acute release of inflammatory mediators induces CAS that may lead to plaque rupture and MI. Type III KS occurs in patients with coronary artery stent-associated thrombosis [11,13-15]. The halo sign and the reversed halo sign of CT are associated with patches of ground-glass opacities at the late phase of COVID-19 infection [16]. Both are mostly seen around the nodules [17]. The halo sign is a GGO surrounding a nodule or mass. It is a circumjacent area of hemorrhage around a lesion and might be seen in some patients with COVID-19. The halo sign and reversed halo sign are nonspecific for COVID-19 infection. They may be seen in invasive pulmonary Aspergillosis, Mucormycosis, Cryptococcosis, pulmonary adenocarcinoma, some types of pulmonary metastasis, tuberculosis, with polyangiitis granulomatosis, thromboembolism, and eosinophilic lung diseases [18].
A 73-year-old married male, a Farmer, non-smoker Egyptian patient was presented to the POC after over 5 years of follow-up with palpitations, dyspnea, and tachypnea. Dizziness, fatigue, loss of appetite, and bilateral lower limb swellings were associated symptoms. He was a daily worker for spraying pesticides for years. He gave a history of two attacks of COVID-19 pneumonia on the 2020th year. The first attack was on August 02, 2020, and was admitted to the intensive care unit (ICU) in the Frescoer Central Hospital and traditionally managed as a COVID-19 pneumonia (Figures 1A, 1B, and 1C). The second attack was on November 07, 2020, and was admitted to the ICU in the same Hospital and was managed as a COVID-19 pneumonia (Figures 1D and 1E). Within one month before both attacks of COVID-19 pneumonia, the patient complained of an episode of severe acute angina with profuse sweating. Unfortunately, the patient neglected this attack of chest pain and didn’t seek medical care. Upon current general physical examination, the patient shows orthopnea, tachypnea, and distressed respiration. The left forehead and face showed profuse sweating (Figure 2). Currently, there is a regular pulse rate (VR of 70), blood pressure (BP) of 100/70 mmHg, respiratory rate of 25 bpm, a temperature of 37.2°C, pulse oximeter of oxygen (O2) saturation of 93%, and GCS of 15/15. Tests for provocative latent tetany were positive. No more relevant clinical data were noted during the clinical examination. The initial ECG tracing was done on the ED on August 02, 2020, showing normal sinus rhythm (NSR), dominant R in V1 with LAD, RBBB, SISIISIII pattern, pathological Q waves in III and aVF leads, sporadic square shape ST-segment elevation in aVR and V1 leads, wide notched QRS complexes, normal PR interval, mimic delta waves, a small single wave between P wave and QRS, biphasic T inversion in V2 and V3 leads. There are T-wave inversions in the anterior leads (V1-5 leads) and ST-segment elevation in aVR, with a mimicked morphology of QRS complexes in V1. There is evidence of the Wavy double sign (Yasser's sign) in V5 and V5 leads (Figure 3A). The second ECG tracing was taken in the ED on August 02, 2020, within 3 minutes of the above tracing showing NSR (VR of 84), dominant R in V1 with the same above changes, but there is evidence of a Wavy double sign (Yasser's sign) in I and II leads and a Wavy triple sign (Yasser's sign) in V6 lead (Figure 3B). The third ECG tracing was done in the ED on November 07, 2020, showing NSR, dominant R in V1 with bigeminal PVCs, LAD, RBBB, SISIISIII pattern, pathological Q waves in III and aVF leads, sporadic square-shaped ST-segment elevation in V1 lead, saddling-shaped ST-segment elevation in V2 lead, and non-specific ST-segment elevation in V2 lead. There is ST-segment depression in V4-6 leads (Figure 3C). The fourth ECG tracing was taken in the ED on November 07, 2020, within 1 minute of the above tracing, showing NSR with the same dominant R in V1, LAD, RBBB, S1S2S3, pathological Q waves in III and aVF leads, sporadic square-shaped ST-segment elevation in aVR and V1 leads, wide notched QRS complexes, normal PR interval, mimic delta waves, a small single-wave between P wave and QRS, biphasic T wave inversion in V2 and V3 leads. There is ST-segment depression in V2-6 leads and T-wave inversions in anterior leads (V1-4). There is a disappearance of the above bigeminal PVCs (Figure 3D). The initial echocardiography was done on December 14, 2020, showed dilated cardiomyopathy, global hypokinesia, severe mitral regurgitation, severe tricuspid regurgitation, moderate aortic regurgitation, moderate pulmonary hypertension, and LV systolic dysfunction with EF 35%. The fifth ECG tracing was taken in the POC on April 20, 2021, within 6 months of the above tracing, showing NSR, dominant R in V1, with LAD, RBBB, SISIISIII pattern, pathological Q waves in III and aVF leads, sporadic square-shaped ST-segment elevation in aVR and V1 lead, wide QRS complexes, prolonged PR interval, mimic delta waves, and a small single wave between P wave and QRS (Figure 3E). The sixth ECG tracing was taken in the POC on December 15, 2023 within 19 months of the above tracing, showing sinus arrhythmia, dominant R in V1, multiple irregular PVCs , premature ventricular couplets with LAD, RBBB, SISIISIII pattern, pathological Q waves in III and aVF leads, sporadic square-shape ST-segment elevation in aVR and V1 leads, saddle-shape ST-segment elevation in aVL, V2, and V3 leads, non-specific ST-segment elevation in V1 lead,wide QRS complexes, prolonged PR interval, mimic delta waves, a small single wave between P wave and QRS, and small R in V4-6 leads (Figure 3F). The seventh ECG tracing was done in the POC on December 15, 2023 within 1 minute of the above tracing, showing sinus arrhythmia, runs of VT, dominant R in V1, multiple irregular PVCs, with LAD, SISIISIII pattern, pathological Q waves in III and aVF leads, sporadic square-shaped ST-segment elevation in aVR lead, saddle-shaped ST-segment elevation in aVL, V2, and V3 leads, non-specific ST-segment elevation in V1 lead, wide QRS complexes, normal PR interval, mimic delta waves, a small single wave between wave P wave and QRS, and small R in V4-6 leads (Figure 3G). Lastly, the patient was admitted to the ICU on March 14, 2024, with decompensated chronic heart failure. Unfortunately, the patient died within 3 days of the ICU admission. The last echocardiography was done on the last ICU admission on 14 March 2024, showing LV dilatation and LV systolic dysfunction with EF 47% (Figure 4). The initial complete blood count (CBC); Hb was 12.4 g/dl, RBCs; 4.47*103/mm3, WBCs; 6.6*103/mm3 (Neutrophils; 66.3 %, Lymphocytes: 27.2%, Monocytes; 6.5%, Eosinophils; 0% and Basophils 0%), Platelets; 205*103/mm3. The plasma sodium on the last ICU admission was 147.4 mmol/l, and serum potassium was 2.9 mmol/l. The plasma sodium was repeated within 5 days of ICU admission, which was (141mmol/l), and serum potassium was (3.21mmol/l). Silent infarction, bifasicular block, dilated cardiomyopathy, and craniofacial hyperhidrosis post-organophosphorus with interlacing COVID-Pneumonia was the most probable diagnosis.
Figure 1: A. Chest XR PA view film was done on 02 August 2020, showing cardiomegaly, a wide mediastinum (light blue arrows), aortic dilatation (red arrow), and an obliterated left angle (green and yellow arrows). B. Shortcuts of chest CT scan were done on 02 August 2020, showing cardiomegaly(white arrow), bilateral mild to moderate pleural effusions (yellow arrows), and pulmonary haziness (red arrow). C. Shortcuts of the same chest CT scan showing the same changes, ground glass consolidations (lime arrow), halo sign (light blue arrow), reversed halo sign (dark blue arrows), and Yasser's lateral halo sign (Yasser's sign: orange arrows). D. Chest XR PA view film was done on 07 November 2020, showing cardiomegaly, wide mediastinum (light blue arrows), aortic dilatation (red arrow), obliterated left angle (blue rectangular and yellow arrow), and an irregular projected right angle (yellow arrow). E. Shortcuts of chest CT scan was done on 07 November 2020, showing ground glass consolidations (lime arrows), bilateral mild to moderate pleural effusions (golden arrows), halo sign (orange arrow), reversed halo sign (light blue arrows), Yasser's lateral halo sign (Yasser's sign: dark blue arrows), and pulmonary haziness (rose arrow).
Figure 2: Photo of the patient from the last presentation to POC showing left-sided craniofacial hyperhidrosis (white arrow) in a smiling patient.
Figure 3: Serial ECG tracings; A. Tracing was done on the ED on August 02, 2020 showing NSR (VR of 85), dominant R in V1 with LAD (brown arrows), RBBB (lime arrow), SISIISIII pattern (light blue arrows), pathological Q waves in III and aVF leads (black arrows), sporadic square-shape ST-segment elevation in aVR and V1 leads ((light blue circle and lime arrow), wide notched QRS complexes (light blue ridge), normal PR interval (pink ridge), mimic delta waves (green and lime arrows), a small single wave between P wave and QRS (golden arrows), biphasic T-wave inversion in V2 and V3 leads. There are T wave inversions in anterior leads (V1-5; light turquoise arrows) and ST-segment elevation in aVR lead (lime arrow) with mimic morphology of QRS complexes in V1. There is evidence of the Wavy double sign (Yasser's sign) in V5 and V5 (dark blue and green arrows).
Figure 3: B. Tracing was done on the ED on August 02, 2020, within 3 minutes of the above tracing showing NSR (VR of 84), dominant R in V1 with the same above changes, but there is evidence of a Wavy double sign (Yasser's sign) in I and II leads (green and dark blue arrows) and a Wavy triple sign (Yasser's sign) in V6 lead (red, green, and dark blue arrows).
Figure 3: C. Tracing was done on the ED on November 07, 2020, showing NSR (VR of 66), dominant R in V1 with bigeminal PVCs (light blue arrows) LAD (green arrows), RBBB (rose arrow), SISIISIII pattern (lime arrows), pathological Q waves in III and aVF leads (red arrows), sporadic square-shaped ST-segment elevation in V1 lead (light blue circle and golden arrows), saddling-shaped ST-segment elevation in V2 lead (pink arrow), and non-specific ST-segment elevation in V2 lead (grey arrow). There is ST-segment depression in V4-6 leads (orange arrows).
Figure 3: D. Tracing was done on the ED on November 07, 2020 within 1 minute of the above tracing showing NSR (VR of 82) with the same dominant R in V1, LAD, RBBB, SISIISIII, pathological Q waves in III and aVF leads, sporadic square-shaped ST-segment elevation in aVR and V1 lead (brown circle and golden arrow), wide notched QRS complexes (green ridge and lime arrows), normal PR interval (dark blue ridge), mimic delta waves (rose arrows), a small single wave between P wave and QRS (golden arrows), biphasic T-wave inversion in V2 and V3 leads. There is ST-segment depression in V2-6 leads (orange arrows) and T wave inversions in anterior leads (V1-4; light turquoise arrows). There is a disappearance of the above bigeminal PVCs.
Figure 3: E. Tracing was done on the POC on April 20, 2021, within 6 months of the above tracing, showing NSR (VR of 62), dominant R in V1, with LAD (green arrows), RBBB (brown circle), SISIISIII pattern (lime arrows), pathological Q waves in III and aVF leads (black arrows), sporadic squared-shaped ST-segment elevation in aVR and V1 leads (light blue circle and golden arrows), wide QRS complexes (green ridge), prolonged PR interval (blue rectangle), mimic delta waves (small red arrows), a small single wave between P wave and QRS (light blue arrows). 
Figure 3: F. Tracing was done on the POC on December 15, 2023 within 19 months of the above tracing, showing sinus arrhythmia (VR of 84), dominant R in V1, multiple irregular PVCs (light blue arrows), premature ventricular couplets (rose arrows) with LAD, RBBB (brown circle), SISIISIII pattern (lime arrows), pathological Q waves in III and aVF leads (red arrows), sporadic square-shape ST-segment elevation in aVR and V1 leads (light blue circle and golden arrows), saddle-shape ST-segment elevation in aVL, V2, and V3 leads (light blue circle and pink arrows), non-specific ST-segment elevation in V1 lead (blue rectangle and light turquoise arrows),wide QRS complexes (green ridge), prolonged PR interval (blue rectangle and light turquoise arrows), mimic delta waves (small lime arrows), small single waves between P wave and QRS (light blue arrows), and small R in V4-6 leads (brown arrows).
Figure 4: G. Tracing was done in the POC on December 15, 2023 within 1 minute of the above tracing, showing sinus arrhythmia (VR of 88), runs of VT (light blue arrows), dominant R in V1 (black arrow), multiple irregular PVCs (rose arrows) with LAD, , SISIISIII pattern, pathological Q waves in III and aVF leads, sporadic square-shaped ST-segment elevation in aVR lead (light blue circle and golden arrow), saddle-shaped ST-segment elevation in aVL, V2, and V3 leads (light blue circle and pink arrows), non-specific ST-segment elevation in V1 lead (light blue arrow), wide QRS complexes (green ridge), normal PR interval (blue rectangle and light turquoise arrows), mimic delta waves (small lime arrows), a small single wave between P wave and QRS (light blue arrows), and small R in V4-6 leads (brown arrows).
Figure 4: A. The last echocardiography was done on the last ICU admission on 14 March 2024, showing LV dilatation (lime arrow) and LV systolic dysfunction with EF 47% (golden arrow).
Yasser's squaring saddling syndrome", "partial modified Yasser's WPW syndrome", and "Yasser's lateral halo sign"
• Overview: Elderly married male, a Farmer, a non-smoker, Egyptian, patient, was presented to the POC after over 5 years of follow-up, after two attacks of COVID-19 pneumonia and neglected and passed myocardial infarction, post-prolonged exposure history of inhalation of organophosphorus.
• The primary objective of my case study was the presence of an elderly married male, a Farmer, non-smoker Egyptian patient, presented with COVID-19 pneumonia, neglected and passed myocardial infarction, and dilated cardiomyopathy in POC.
• The secondary objective for my case study was the question of: how did you manage the case?
• An episode of severe acute angina with profuse sweating one month before both attacks of COVID-19 pneumonia and later evidence of pathological Q waves in the inferior leads suggestive of inferior myocardial infarction.
• On applying the "Naranjo Algorithm-Adverse Drug Reaction (ADR) Probability Scale", the prolonged exposure history of inhalation of organophosphorus is more definiteas a cause for this infarction (Table 1).
• Both attacks of COVID-19 pneumonia on the 2020th year were evidenced in the admission history in the ICU and radiological workup (Figures 1A-D).
• Radiological cardiomegaly, global hypokinesia, LV systolic dysfunction, dilated cardiac chambers, and multiple valvular disorders will strengthen the diagnosis of dilated cardiomyopathy.
• There are sporadic and randomly beats of square-shaped ST-segment elevations in aVR and V1 leads of various serial ECG tracings (Figures 3A-G). The restriction of square-shaped ST-segment elevation to aVR and V1 leads is interesting. There is no clear or interpreted pathogenesis. But both depolarization and repolarization changes may be implicated.
• There are also sporadic and randomly beating saddling-shaped ST-segment elevations in aVL, V2, and V3 leads of various serial ECG tracings (Figures 3C, 3F, and 3G). The restriction of square-shaped ST-segment elevation to aVL, V2, and V3 leads is interesting. There is no clear or interpreted pathogenesis. But also, both depolarization and repolarization changes may be implicated.
The combination of squared-shaped ST-segment elevations in aVR and V1 leads (Figures 3A-G) and saddling-shaped ST-segment elevations in aVL, V2, and V3 leads (Figures 3C, 3F, and 3G) is new described and named as, "Yasser's Squaring Saddling Syndrome" (Figures 5).
• There is also a sporadic and randomly wide QRS complex, normal PR interval, mimicking delta waves, and a small single wave between the P wave and QRS complex. This small single wave between P-waves is smaller than the previous P wave and located between the later QRS complex and the preceding P wave (Figures 3A, 3D, 3E, 3F, and 3G).
• The preceding PR interval for this included a wide QRS complex is normal in duration.
• This combination of sporadic mimicking delta waves with a wide QRS complex, normal PR interval, and a small single wave between the P wave and QRS complex is newly described and named as "Partial Modified Yasser's WPW Syndrome" (Figures 5).
• There is a fixed bifasicular heart block in nearly all ECG tracings except tracing 3E and 3F (Figures 3E, 3F), showing prolongation of the PR interval, which indicates of transient trifasicular heart block.
• The presence of the right and the left lateral Halo sign is newly described, other than the Halo sign and Reversed Halo sign [16-18], and named as "Yasser's Lateral Halo Sign" (Figures 5). The author thinks that the necrosis in a small COVID-19 lesion or nodule toward the lateral side may be an interpretative theory.
Figure 5 Graphical presentation of "Yasser's squaring saddling syndrome", "partial modified Yasser's WPW syndrome", and "Yasser's lateral halo sign".
| Question | Yes | No | Do Not Know | Score |
|---|---|---|---|---|
| 1. Are there previous conclusive reports on this reaction? | +1 | 0 | 0 | +1 |
| 2. Did the adverse event appear after the suspected drug was administered? | +2 | -1 | 0 | +2 |
| 3. Did the adverse event improve when the drug was discontinued or a specific antagonist was administered? | +1 | 0 | 0 | +1 |
| 4. Did the adverse event reappear when the drug was readministered? | +2 | -1 | 0 | +2 |
| 5. Are there alternative causes that could on their own have caused the reaction? | -1 | +2 | 0 | +2 |
| 6. Did the reaction reappear when a placebo was given? | -1 | +1 | 0 | 0 |
| 7. Was the drug detected in blood or other fluids in concentrations known to be toxic? | +1 | 0 | 0 | 0 |
| 8. Was the reaction more severe when the dose was increased or less severe when the dose was decreased? | +1 | 0 | 0 | +1 |
| 9. Did the patient have a similar reaction to the same or similar drugs in any previous exposure? | +1 | 0 | 0 | +1 |
| 10. Was the adverse event confirmed by any objective evidence? | +1 | 0 | 0 | +1 |
| Total Score: +11 | ||||
• This patient had a strong voice character, stiffness, but mostly smiley on a talk.
• The presence of senility, old myocardial infarction, two attacks of COVID-19 pneumonia, fixed bifasicular heart block, transient trifasicular heart block, dilated cardiomyopathy, bigeminal PVCs, multiple irregular PVCs, premature ventricular couplets, runs of VT, and LV systolic dysfunction with global hypokinesia are considered risk factors.
• The most differential diagnoses for the serial ECG are Brugada syndrome, WPW syndrome, and acute myocardial infarction. But all ECG criteria are against them.
• I can’t compare the current case with similar conditions. There are no a similar or known cases with the same management for near comparison.
• The only limitation of the current study was the unavailability of an electrophysiological study and coronary angiography.
"Yasser's squaring saddling syndrome", "partial modified Yasser's WPW syndrome", and "Yasser's lateral halo sign" are new cardiovascular and radiological discoveries.
• Senility, chronic exposure to organophosphates, old myocardial infarction, two attacks of COVID-19 pneumonia, fixed bifasicular heart block, transient trifasicular heart block, dilated cardiomyopathy, bigeminal premature ventricular complexes (PVCs), multiple irregular PVCs, premature ventricular couplets, runs of ventricular tachycardia (VT), and left ventricular (LV) systolic dysfunction with global hypokinesia are serious constellation risk factors.
• Further wide studies will be recommended.
Conflicts of interest
• There are no conflicts of interest.
Acknowledgment
• I wish to thank my wife for saving time and improving the conditions for helping me.
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Dear Agrippa Hilda, Journal of Neuroscience and Neurological Surgery, Editorial Coordinator, I trust this message finds you well. I want to extend my appreciation for considering my article for publication in your esteemed journal. I am pleased to provide a testimonial regarding the peer review process and the support received from your editorial office. The peer review process for my paper was carried out in a highly professional and thorough manner. The feedback and comments provided by the authors were constructive and very useful in improving the quality of the manuscript. This rigorous assessment process undoubtedly contributes to the high standards maintained by your journal.
International Journal of Clinical Case Reports and Reviews. I strongly recommend to consider submitting your work to this high-quality journal. The support and availability of the Editorial staff is outstanding and the review process was both efficient and rigorous.
Thank you very much for publishing my Research Article titled “Comparing Treatment Outcome Of Allergic Rhinitis Patients After Using Fluticasone Nasal Spray And Nasal Douching" in the Journal of Clinical Otorhinolaryngology. As Medical Professionals we are immensely benefited from study of various informative Articles and Papers published in this high quality Journal. I look forward to enriching my knowledge by regular study of the Journal and contribute my future work in the field of ENT through the Journal for use by the medical fraternity. The support from the Editorial office was excellent and very prompt. I also welcome the comments received from the readers of my Research Article.
Dear Erica Kelsey, Editorial Coordinator of Cancer Research and Cellular Therapeutics Our team is very satisfied with the processing of our paper by your journal. That was fast, efficient, rigorous, but without unnecessary complications. We appreciated the very short time between the submission of the paper and its publication on line on your site.
I am very glad to say that the peer review process is very successful and fast and support from the Editorial Office. Therefore, I would like to continue our scientific relationship for a long time. And I especially thank you for your kindly attention towards my article. Have a good day!
"We recently published an article entitled “Influence of beta-Cyclodextrins upon the Degradation of Carbofuran Derivatives under Alkaline Conditions" in the Journal of “Pesticides and Biofertilizers” to show that the cyclodextrins protect the carbamates increasing their half-life time in the presence of basic conditions This will be very helpful to understand carbofuran behaviour in the analytical, agro-environmental and food areas. We greatly appreciated the interaction with the editor and the editorial team; we were particularly well accompanied during the course of the revision process, since all various steps towards publication were short and without delay".
I would like to express my gratitude towards you process of article review and submission. I found this to be very fair and expedient. Your follow up has been excellent. I have many publications in national and international journal and your process has been one of the best so far. Keep up the great work.
We are grateful for this opportunity to provide a glowing recommendation to the Journal of Psychiatry and Psychotherapy. We found that the editorial team were very supportive, helpful, kept us abreast of timelines and over all very professional in nature. The peer review process was rigorous, efficient and constructive that really enhanced our article submission. The experience with this journal remains one of our best ever and we look forward to providing future submissions in the near future.
I am very pleased to serve as EBM of the journal, I hope many years of my experience in stem cells can help the journal from one way or another. As we know, stem cells hold great potential for regenerative medicine, which are mostly used to promote the repair response of diseased, dysfunctional or injured tissue using stem cells or their derivatives. I think Stem Cell Research and Therapeutics International is a great platform to publish and share the understanding towards the biology and translational or clinical application of stem cells.
I would like to give my testimony in the support I have got by the peer review process and to support the editorial office where they were of asset to support young author like me to be encouraged to publish their work in your respected journal and globalize and share knowledge across the globe. I really give my great gratitude to your journal and the peer review including the editorial office.
I am delighted to publish our manuscript entitled "A Perspective on Cocaine Induced Stroke - Its Mechanisms and Management" in the Journal of Neuroscience and Neurological Surgery. The peer review process, support from the editorial office, and quality of the journal are excellent. The manuscripts published are of high quality and of excellent scientific value. I recommend this journal very much to colleagues.
Dr.Tania Muñoz, My experience as researcher and author of a review article in The Journal Clinical Cardiology and Interventions has been very enriching and stimulating. The editorial team is excellent, performs its work with absolute responsibility and delivery. They are proactive, dynamic and receptive to all proposals. Supporting at all times the vast universe of authors who choose them as an option for publication. The team of review specialists, members of the editorial board, are brilliant professionals, with remarkable performance in medical research and scientific methodology. Together they form a frontline team that consolidates the JCCI as a magnificent option for the publication and review of high-level medical articles and broad collective interest. I am honored to be able to share my review article and open to receive all your comments.
“The peer review process of JPMHC is quick and effective. Authors are benefited by good and professional reviewers with huge experience in the field of psychology and mental health. The support from the editorial office is very professional. People to contact to are friendly and happy to help and assist any query authors might have. Quality of the Journal is scientific and publishes ground-breaking research on mental health that is useful for other professionals in the field”.
Dear editorial department: On behalf of our team, I hereby certify the reliability and superiority of the International Journal of Clinical Case Reports and Reviews in the peer review process, editorial support, and journal quality. Firstly, the peer review process of the International Journal of Clinical Case Reports and Reviews is rigorous, fair, transparent, fast, and of high quality. The editorial department invites experts from relevant fields as anonymous reviewers to review all submitted manuscripts. These experts have rich academic backgrounds and experience, and can accurately evaluate the academic quality, originality, and suitability of manuscripts. The editorial department is committed to ensuring the rigor of the peer review process, while also making every effort to ensure a fast review cycle to meet the needs of authors and the academic community. Secondly, the editorial team of the International Journal of Clinical Case Reports and Reviews is composed of a group of senior scholars and professionals with rich experience and professional knowledge in related fields. The editorial department is committed to assisting authors in improving their manuscripts, ensuring their academic accuracy, clarity, and completeness. Editors actively collaborate with authors, providing useful suggestions and feedback to promote the improvement and development of the manuscript. We believe that the support of the editorial department is one of the key factors in ensuring the quality of the journal. Finally, the International Journal of Clinical Case Reports and Reviews is renowned for its high- quality articles and strict academic standards. The editorial department is committed to publishing innovative and academically valuable research results to promote the development and progress of related fields. The International Journal of Clinical Case Reports and Reviews is reasonably priced and ensures excellent service and quality ratio, allowing authors to obtain high-level academic publishing opportunities in an affordable manner. I hereby solemnly declare that the International Journal of Clinical Case Reports and Reviews has a high level of credibility and superiority in terms of peer review process, editorial support, reasonable fees, and journal quality. Sincerely, Rui Tao.
Clinical Cardiology and Cardiovascular Interventions I testity the covering of the peer review process, support from the editorial office, and quality of the journal.
Clinical Cardiology and Cardiovascular Interventions, we deeply appreciate the interest shown in our work and its publication. It has been a true pleasure to collaborate with you. The peer review process, as well as the support provided by the editorial office, have been exceptional, and the quality of the journal is very high, which was a determining factor in our decision to publish with you.
The peer reviewers process is quick and effective, the supports from editorial office is excellent, the quality of journal is high. I would like to collabroate with Internatioanl journal of Clinical Case Reports and Reviews journal clinically in the future time.
Clinical Cardiology and Cardiovascular Interventions, I would like to express my sincerest gratitude for the trust placed in our team for the publication in your journal. It has been a true pleasure to collaborate with you on this project. I am pleased to inform you that both the peer review process and the attention from the editorial coordination have been excellent. Your team has worked with dedication and professionalism to ensure that your publication meets the highest standards of quality. We are confident that this collaboration will result in mutual success, and we are eager to see the fruits of this shared effort.
Dear Dr. Jessica Magne, Editorial Coordinator 0f Clinical Cardiology and Cardiovascular Interventions, I hope this message finds you well. I want to express my utmost gratitude for your excellent work and for the dedication and speed in the publication process of my article titled "Navigating Innovation: Qualitative Insights on Using Technology for Health Education in Acute Coronary Syndrome Patients." I am very satisfied with the peer review process, the support from the editorial office, and the quality of the journal. I hope we can maintain our scientific relationship in the long term.
Dear Monica Gissare, - Editorial Coordinator of Nutrition and Food Processing. ¨My testimony with you is truly professional, with a positive response regarding the follow-up of the article and its review, you took into account my qualities and the importance of the topic¨.
Dear Dr. Jessica Magne, Editorial Coordinator 0f Clinical Cardiology and Cardiovascular Interventions, The review process for the article “The Handling of Anti-aggregants and Anticoagulants in the Oncologic Heart Patient Submitted to Surgery” was extremely rigorous and detailed. From the initial submission to the final acceptance, the editorial team at the “Journal of Clinical Cardiology and Cardiovascular Interventions” demonstrated a high level of professionalism and dedication. The reviewers provided constructive and detailed feedback, which was essential for improving the quality of our work. Communication was always clear and efficient, ensuring that all our questions were promptly addressed. The quality of the “Journal of Clinical Cardiology and Cardiovascular Interventions” is undeniable. It is a peer-reviewed, open-access publication dedicated exclusively to disseminating high-quality research in the field of clinical cardiology and cardiovascular interventions. The journal's impact factor is currently under evaluation, and it is indexed in reputable databases, which further reinforces its credibility and relevance in the scientific field. I highly recommend this journal to researchers looking for a reputable platform to publish their studies.
Dear Editorial Coordinator of the Journal of Nutrition and Food Processing! "I would like to thank the Journal of Nutrition and Food Processing for including and publishing my article. The peer review process was very quick, movement and precise. The Editorial Board has done an extremely conscientious job with much help, valuable comments and advices. I find the journal very valuable from a professional point of view, thank you very much for allowing me to be part of it and I would like to participate in the future!”
Dealing with The Journal of Neurology and Neurological Surgery was very smooth and comprehensive. The office staff took time to address my needs and the response from editors and the office was prompt and fair. I certainly hope to publish with this journal again.Their professionalism is apparent and more than satisfactory. Susan Weiner
My Testimonial Covering as fellowing: Lin-Show Chin. The peer reviewers process is quick and effective, the supports from editorial office is excellent, the quality of journal is high. I would like to collabroate with Internatioanl journal of Clinical Case Reports and Reviews.
My experience publishing in Psychology and Mental Health Care was exceptional. The peer review process was rigorous and constructive, with reviewers providing valuable insights that helped enhance the quality of our work. The editorial team was highly supportive and responsive, making the submission process smooth and efficient. The journal's commitment to high standards and academic rigor makes it a respected platform for quality research. I am grateful for the opportunity to publish in such a reputable journal.
My experience publishing in International Journal of Clinical Case Reports and Reviews was exceptional. I Come forth to Provide a Testimonial Covering the Peer Review Process and the editorial office for the Professional and Impartial Evaluation of the Manuscript.
I would like to offer my testimony in the support. I have received through the peer review process and support the editorial office where they are to support young authors like me, encourage them to publish their work in your esteemed journals, and globalize and share knowledge globally. I really appreciate your journal, peer review, and editorial office.
Dear Agrippa Hilda- Editorial Coordinator of Journal of Neuroscience and Neurological Surgery, "The peer review process was very quick and of high quality, which can also be seen in the articles in the journal. The collaboration with the editorial office was very good."
I would like to express my sincere gratitude for the support and efficiency provided by the editorial office throughout the publication process of my article, “Delayed Vulvar Metastases from Rectal Carcinoma: A Case Report.” I greatly appreciate the assistance and guidance I received from your team, which made the entire process smooth and efficient. The peer review process was thorough and constructive, contributing to the overall quality of the final article. I am very grateful for the high level of professionalism and commitment shown by the editorial staff, and I look forward to maintaining a long-term collaboration with the International Journal of Clinical Case Reports and Reviews.
To Dear Erin Aust, I would like to express my heartfelt appreciation for the opportunity to have my work published in this esteemed journal. The entire publication process was smooth and well-organized, and I am extremely satisfied with the final result. The Editorial Team demonstrated the utmost professionalism, providing prompt and insightful feedback throughout the review process. Their clear communication and constructive suggestions were invaluable in enhancing my manuscript, and their meticulous attention to detail and dedication to quality are truly commendable. Additionally, the support from the Editorial Office was exceptional. From the initial submission to the final publication, I was guided through every step of the process with great care and professionalism. The team's responsiveness and assistance made the entire experience both easy and stress-free. I am also deeply impressed by the quality and reputation of the journal. It is an honor to have my research featured in such a respected publication, and I am confident that it will make a meaningful contribution to the field.
"I am grateful for the opportunity of contributing to [International Journal of Clinical Case Reports and Reviews] and for the rigorous review process that enhances the quality of research published in your esteemed journal. I sincerely appreciate the time and effort of your team who have dedicatedly helped me in improvising changes and modifying my manuscript. The insightful comments and constructive feedback provided have been invaluable in refining and strengthening my work".
I thank the ‘Journal of Clinical Research and Reports’ for accepting this article for publication. This is a rigorously peer reviewed journal which is on all major global scientific data bases. I note the review process was prompt, thorough and professionally critical. It gave us an insight into a number of important scientific/statistical issues. The review prompted us to review the relevant literature again and look at the limitations of the study. The peer reviewers were open, clear in the instructions and the editorial team was very prompt in their communication. This journal certainly publishes quality research articles. I would recommend the journal for any future publications.
Dear Jessica Magne, with gratitude for the joint work. Fast process of receiving and processing the submitted scientific materials in “Clinical Cardiology and Cardiovascular Interventions”. High level of competence of the editors with clear and correct recommendations and ideas for enriching the article.
We found the peer review process quick and positive in its input. The support from the editorial officer has been very agile, always with the intention of improving the article and taking into account our subsequent corrections.
My article, titled 'No Way Out of the Smartphone Epidemic Without Considering the Insights of Brain Research,' has been republished in the International Journal of Clinical Case Reports and Reviews. The review process was seamless and professional, with the editors being both friendly and supportive. I am deeply grateful for their efforts.
To Dear Erin Aust – Editorial Coordinator of Journal of General Medicine and Clinical Practice! I declare that I am absolutely satisfied with your work carried out with great competence in following the manuscript during the various stages from its receipt, during the revision process to the final acceptance for publication. Thank Prof. Elvira Farina
Dear Jessica, and the super professional team of the ‘Clinical Cardiology and Cardiovascular Interventions’ I am sincerely grateful to the coordinated work of the journal team for the no problem with the submission of my manuscript: “Cardiometabolic Disorders in A Pregnant Woman with Severe Preeclampsia on the Background of Morbid Obesity (Case Report).” The review process by 5 experts was fast, and the comments were professional, which made it more specific and academic, and the process of publication and presentation of the article was excellent. I recommend that my colleagues publish articles in this journal, and I am interested in further scientific cooperation. Sincerely and best wishes, Dr. Oleg Golyanovskiy.
Dear Ashley Rosa, Editorial Coordinator of the journal - Psychology and Mental Health Care. " The process of obtaining publication of my article in the Psychology and Mental Health Journal was positive in all areas. The peer review process resulted in a number of valuable comments, the editorial process was collaborative and timely, and the quality of this journal has been quickly noticed, resulting in alternative journals contacting me to publish with them." Warm regards, Susan Anne Smith, PhD. Australian Breastfeeding Association.
Dear Jessica Magne, Editorial Coordinator, Clinical Cardiology and Cardiovascular Interventions, Auctores Publishing LLC. I appreciate the journal (JCCI) editorial office support, the entire team leads were always ready to help, not only on technical front but also on thorough process. Also, I should thank dear reviewers’ attention to detail and creative approach to teach me and bring new insights by their comments. Surely, more discussions and introduction of other hemodynamic devices would provide better prevention and management of shock states. Your efforts and dedication in presenting educational materials in this journal are commendable. Best wishes from, Farahnaz Fallahian.
Dear Maria Emerson, Editorial Coordinator, International Journal of Clinical Case Reports and Reviews, Auctores Publishing LLC. I am delighted to have published our manuscript, "Acute Colonic Pseudo-Obstruction (ACPO): A rare but serious complication following caesarean section." I want to thank the editorial team, especially Maria Emerson, for their prompt review of the manuscript, quick responses to queries, and overall support. Yours sincerely Dr. Victor Olagundoye.
Dear Ashley Rosa, Editorial Coordinator, International Journal of Clinical Case Reports and Reviews. Many thanks for publishing this manuscript after I lost confidence the editors were most helpful, more than other journals Best wishes from, Susan Anne Smith, PhD. Australian Breastfeeding Association.
Dear Agrippa Hilda, Editorial Coordinator, Journal of Neuroscience and Neurological Surgery. The entire process including article submission, review, revision, and publication was extremely easy. The journal editor was prompt and helpful, and the reviewers contributed to the quality of the paper. Thank you so much! Eric Nussbaum, MD
Dr Hala Al Shaikh This is to acknowledge that the peer review process for the article ’ A Novel Gnrh1 Gene Mutation in Four Omani Male Siblings, Presentation and Management ’ sent to the International Journal of Clinical Case Reports and Reviews was quick and smooth. The editorial office was prompt with easy communication.
Dear Erin Aust, Editorial Coordinator, Journal of General Medicine and Clinical Practice. We are pleased to share our experience with the “Journal of General Medicine and Clinical Practice”, following the successful publication of our article. The peer review process was thorough and constructive, helping to improve the clarity and quality of the manuscript. We are especially thankful to Ms. Erin Aust, the Editorial Coordinator, for her prompt communication and continuous support throughout the process. Her professionalism ensured a smooth and efficient publication experience. The journal upholds high editorial standards, and we highly recommend it to fellow researchers seeking a credible platform for their work. Best wishes By, Dr. Rakhi Mishra.
Dear Jessica Magne, Editorial Coordinator, Clinical Cardiology and Cardiovascular Interventions, Auctores Publishing LLC. The peer review process of the journal of Clinical Cardiology and Cardiovascular Interventions was excellent and fast, as was the support of the editorial office and the quality of the journal. Kind regards Walter F. Riesen Prof. Dr. Dr. h.c. Walter F. Riesen.
Dear Ashley Rosa, Editorial Coordinator, International Journal of Clinical Case Reports and Reviews, Auctores Publishing LLC. Thank you for publishing our article, Exploring Clozapine's Efficacy in Managing Aggression: A Multiple Single-Case Study in Forensic Psychiatry in the international journal of clinical case reports and reviews. We found the peer review process very professional and efficient. The comments were constructive, and the whole process was efficient. On behalf of the co-authors, I would like to thank you for publishing this article. With regards, Dr. Jelle R. Lettinga.
Dear Clarissa Eric, Editorial Coordinator, Journal of Clinical Case Reports and Studies, I would like to express my deep admiration for the exceptional professionalism demonstrated by your journal. I am thoroughly impressed by the speed of the editorial process, the substantive and insightful reviews, and the meticulous preparation of the manuscript for publication. Additionally, I greatly appreciate the courteous and immediate responses from your editorial office to all my inquiries. Best Regards, Dariusz Ziora
Dear Chrystine Mejia, Editorial Coordinator, Journal of Neurodegeneration and Neurorehabilitation, Auctores Publishing LLC, We would like to thank the editorial team for the smooth and high-quality communication leading up to the publication of our article in the Journal of Neurodegeneration and Neurorehabilitation. The reviewers have extensive knowledge in the field, and their relevant questions helped to add value to our publication. Kind regards, Dr. Ravi Shrivastava.
Dear Clarissa Eric, Editorial Coordinator, Journal of Clinical Case Reports and Studies, Auctores Publishing LLC, USA Office: +1-(302)-520-2644. I would like to express my sincere appreciation for the efficient and professional handling of my case report by the ‘Journal of Clinical Case Reports and Studies’. The peer review process was not only fast but also highly constructive—the reviewers’ comments were clear, relevant, and greatly helped me improve the quality and clarity of my manuscript. I also received excellent support from the editorial office throughout the process. Communication was smooth and timely, and I felt well guided at every stage, from submission to publication. The overall quality and rigor of the journal are truly commendable. I am pleased to have published my work with Journal of Clinical Case Reports and Studies, and I look forward to future opportunities for collaboration. Sincerely, Aline Tollet, UCLouvain.
Dear Ms. Mayra Duenas, Editorial Coordinator, International Journal of Clinical Case Reports and Reviews. “The International Journal of Clinical Case Reports and Reviews represented the “ideal house” to share with the research community a first experience with the use of the Simeox device for speech rehabilitation. High scientific reputation and attractive website communication were first determinants for the selection of this Journal, and the following submission process exceeded expectations: fast but highly professional peer review, great support by the editorial office, elegant graphic layout. Exactly what a dynamic research team - also composed by allied professionals - needs!" From, Chiara Beccaluva, PT - Italy.
Dear Maria Emerson, Editorial Coordinator, we have deeply appreciated the professionalism demonstrated by the International Journal of Clinical Case Reports and Reviews. The reviewers have extensive knowledge of our field and have been very efficient and fast in supporting the process. I am really looking forward to further collaboration. Thanks. Best regards, Dr. Claudio Ligresti
Dear Chrystine Mejia, Editorial Coordinator, Journal of Neurodegeneration and Neurorehabilitation. “The peer review process was efficient and constructive, and the editorial office provided excellent communication and support throughout. The journal ensures scientific rigor and high editorial standards, while also offering a smooth and timely publication process. We sincerely appreciate the work of the editorial team in facilitating the dissemination of innovative approaches such as the Bonori Method.” Best regards, Dr. Matteo Bonori.
I recommend without hesitation submitting relevant papers on medical decision making to the International Journal of Clinical Case Reports and Reviews. I am very grateful to the editorial staff. Maria Emerson was a pleasure to communicate with. The time from submission to publication was an extremely short 3 weeks. The editorial staff submitted the paper to three reviewers. Two of the reviewers commented positively on the value of publishing the paper. The editorial staff quickly recognized the third reviewer’s comments as an unjust attempt to reject the paper. I revised the paper as recommended by the first two reviewers.
Dear Maria Emerson, Editorial Coordinator, Journal of Clinical Research and Reports. Thank you for publishing our case report: "Clinical Case of Effective Fetal Stem Cells Treatment in a Patient with Autism Spectrum Disorder" within the "Journal of Clinical Research and Reports" being submitted by the team of EmCell doctors from Kyiv, Ukraine. We much appreciate a professional and transparent peer-review process from Auctores. All research Doctors are so grateful to your Editorial Office and Auctores Publishing support! I amiably wish our article publication maintained a top quality of your International Scientific Journal. My best wishes for a prosperity of the Journal of Clinical Research and Reports. Hope our scientific relationship and cooperation will remain long lasting. Thank you very much indeed. Kind regards, Dr. Andriy Sinelnyk Cell Therapy Center EmCell
Dear Editorial Team, Clinical Cardiology and Cardiovascular Interventions. It was truly a rewarding experience to work with the journal “Clinical Cardiology and Cardiovascular Interventions”. The peer review process was insightful and encouraging, helping us refine our work to a higher standard. The editorial office offered exceptional support with prompt and thoughtful communication. I highly value the journal’s role in promoting scientific advancement and am honored to be part of it. Best regards, Meng-Jou Lee, MD, Department of Anesthesiology, National Taiwan University Hospital.
Dear Editorial Team, Journal-Clinical Cardiology and Cardiovascular Interventions, “Publishing my article with Clinical Cardiology and Cardiovascular Interventions has been a highly positive experience. The peer-review process was rigorous yet supportive, offering valuable feedback that strengthened my work. The editorial team demonstrated exceptional professionalism, prompt communication, and a genuine commitment to maintaining the highest scientific standards. I am very pleased with the publication quality and proud to be associated with such a reputable journal.” Warm regards, Dr. Mahmoud Kamal Moustafa Ahmed
Dear Maria Emerson, Editorial Coordinator of ‘International Journal of Clinical Case Reports and Reviews’, I appreciate the opportunity to publish my article with your journal. The editorial office provided clear communication during the submission and review process, and I found the overall experience professional and constructive. Best regards, Elena Salvatore.
Dear Mayra Duenas, Editorial Coordinator of ‘International Journal of Clinical Case Reports and Reviews Herewith I confirm an optimal peer review process and a great support of the editorial office of the present journal
Dear Editorial Team, Clinical Cardiology and Cardiovascular Interventions. I am really grateful for the peers review; their feedback gave me the opportunity to reflect on the message and impact of my work and to ameliorate the article. The editors did a great job in addition by encouraging me to continue with the process of publishing.
Dear Cecilia Lilly, Editorial Coordinator, Endocrinology and Disorders, Thank you so much for your quick response regarding reviewing and all process till publishing our manuscript entitled: Prevalence of Pre-Diabetes and its Associated Risk Factors Among Nile College Students, Sudan. Best regards, Dr Mamoun Magzoub.
International Journal of Clinical Case Reports and Reviews is a high quality journal that has a clear and concise submission process. The peer review process was comprehensive and constructive. Support from the editorial office was excellent, since the administrative staff were responsive. The journal provides a fast and timely publication timeline.
Dear Maria Emerson, Editorial Coordinator of International Journal of Clinical Case Reports and Reviews, What distinguishes International Journal of Clinical Case Report and Review is not only the scientific rigor of its publications, but the intellectual climate in which research is evaluated. The submission process is refreshingly free of unnecessary formal barriers and bureaucratic rituals that often complicate academic publishing without adding real value. The peer-review system is demanding yet constructive, guided by genuine scientific dialogue rather than hierarchical or authoritarian attitudes. Reviewers act as collaborators in improving the manuscript, not as gatekeepers imposing arbitrary standards. This journal offers a rare balance: high methodological standards combined with a respectful, transparent, and supportive editorial approach. In an era where publishing can feel more burdensome than research itself, this platform restores the original purpose of peer review — to refine ideas, not to obstruct them Prof. Perlat Kapisyzi, FCCP PULMONOLOGIST AND THORACIC IMAGING.
Dear Grace Pierce, International Journal of Clinical Case Reports and Reviews I appreciate the opportunity to review for Auctore Journal, as the overall editorial process was smooth, transparent and professionally managed. This journal maintains high scientific standards and ensures timely communications with authors, which is truly commendable. I would like to express my special thanks to editor Grace Pierce for his constant guidance, promt responses, and supportive coordination throughout the review process. I am also greatful to Eleanor Bailey from the finance department for her clear communication and efficient handling of all administrative matters. Overall, my experience with Auctore Journal has been highly positive and rewarding. Best regards, Sabita sinha
Dear Mayra Duenas, Editorial Coordinator of the journal IJCCR, I write here a little on my experience as an author submitting to the International Journal of Clinical Case Reports and Reviews (IJCCR). This was my first submission to IJCCR and my manuscript was inherently an outsider’s effort. It attempted to broadly identify and then make some sense of life’s under-appreciated mysteries. I initially had responded to a request for possible submissions. I then contacted IJCCR with a tentative topic for a manuscript. They quickly got back with an approval for the submission, but with a particular requirement that it be medically relevant. I then put together a manuscript and submitted it. After the usual back-and-forth over forms and formality, the manuscript was sent off for reviews. Within 2 weeks I got back 4 reviews which were both helpful and also surprising. Surprising in that the topic was somewhat foreign to medical literature. My subsequent updates in response to the reviewer comments went smoothly and in short order I had a series of proofs to evaluate. All in all, the whole publication process seemed outstanding. It was both helpful in terms of the paper’s content and also in terms of its efficient and friendly communications. Thank you all very much. Sincerely, Ted Christopher, Rochester, NY.
