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Research Article | DOI: https://doi.org/10.31579/2641-0419/530
1Cardiology Service of the CHU Ignace Deen, Guinea, Conakry.
2Sino-Guinean Friendship Hospital (HASGUI), Guinea, Conakry.
*Corresponding Author: Bassirou Mamadou Bah, Cardiology Service of the CHU Ignace Deen, Guinea, Conakry.
Citation: Bassirou M. Bah, Balde E. Yaya, Balde T. Siradio, Camara O. Mamadama, Doumbouya A. Diouldé, et al, (2025), Venous Thromboembolic Disease: Epidemiological, Clinical and Therapeutic Aspects in the Cardiology Department of the Ignace Deen National Hospital, J Clinical Cardiology and Cardiovascular Interventions, 9(3); DOI:10.31579/2641-0419/530
Copyright: © 2025, Bassirou Mamadou Bah. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Received: 12 September 2025 | Accepted: 09 January 2026 | Published: 26 January 2026
Keywords: pulmonary embolism; deep vein thrombosis; chu
Introduction: Venous thromboembolic disease (VTE) is an anatomical and clinical entity characterized by the formation of a blood clot (thrombus) that blocks a vein and impedes blood circulation. The most common manifestations are deep vein thrombosis, which usually occurs in the lower limbs, and pulmonary embolism. Our objective was to contribute to the improvement of the management of thromboembolic diseases in the Cardiology department of the National Ignace-Deen Hospital.
Material and method: It was a longitudinal descriptive prospective study lasting 6 months.
Result: The hospital frequency in our study was 14.28%. The age group 45 to 55 years was the most represented, with a female predominance, at 64.51%. Among the 31 cases of VTE, 7 patients (22.58%) had isolated DVT, 21 patients (61.74%) had PE without prior diagnosis of venous thrombosis and 3 patients (9.68%) had venous thrombosis complicated by pulmonary embolism. Edema and pain in the lower limb were the predominant clinical manifestation of DVT, 29.03%. Tachycardia, dyspnea and chest pain were almost constant in the EP, i.e. 100%; 9.68% of patients presented complications such as pulmonary embolism with hemodynamic instability.
Conclusion: According to this study, VTE affects women and subjects between 45 and 55 years much more.
Venous thromboembolic disease (VTE) is a unique entity that includes two clinical forms: deep vein thrombosis (DVT) and its major complication, pulmonary embolism (PE) [1]. Deep vein thrombosis is inseparable from pulmonary embolism (immediate complication), since 70% to 90% of pulmonary embolisms are consecutive to deep vein thrombosis. [2].
VTE is a common and potentially life-threatening condition. Due to its impact on morbidity and mortality and medical costs, VTE still represents a major public health issue [1]
The global prevalence is estimated at 1.6 per 1000 inhabitants [3]. According to estimates made at the 1997 Consensus Conference on Prevention of Venous Thromboembolic Events, the annual incidence of DVT was 160/100,000, that of symptomatic (non-fatal) PE was 20/100,000 and that of fatal (post-mortem) of 50/100 000 [4].
In sub-Saharan Africa, it constitutes a real public health problem with a prevalence between 2.7 and 9.12% [5]. However, some studies carried out in a hospital setting give prevalence varying from one country to another. In Senegal, the prevalence of deep vein thrombosis was 2,78% [6]; it was 1.6% in Cameroon [7]. A study conducted in Bamako in 2015 (published in 2019) revealed that VTE constituted 4.02% of hospitalizations in the cardiology department of the Gabriel TOURE hospital [8].
It also presents late complications such as post-thrombotic venous disease and post-embolic pulmonary arterial hypertension [9,10].
In view of these data, we have initiated this study with the aim of evaluating the epidemic-clinical, paraclinical, and therapeutic aspects of venous thromboembolic disease in the cardiology department of the Ignace Deen national hospital.
II-1-Nature, framework and period of the study:
It was a descriptive prospective study conducted in the cardiology department of the Ignace Deen University Hospital Center, over a period of six (6) months from March 1 to September 30, 2024.
II-2 Selection criteria and diagnosis of VTE
Were included in our study:
All patients hospitalized for imaging-confirmed venous thromboembolic disease. We used the pulmonary angioscanner for the diagnosis of pulmonary embolism and the venous Doppler ultrasound of the lower limbs for venous thrombosis of the lower limbs.
The thoracic angioscanner was performed immediately in patients who had high clinical probabilities assessed by the revised Geneva score and after positive D-Dimer assay in patients with low and intermediate clinical probabilities.
Patients who did not perform a thoracic mangowran and/or venous Doppler ultrasound of the lower limbs were excluded.
II.3 Study variables
Our study variables were qualitative and quantitative and focused on sociodemographic, clinical, paraclinical, and therapeutic data.
II.3.1 socio-demographic variables: concern age and sex.
II.3-2 clinical variables: all the patients included benefited from an interrogation and a clinical examination to research:
II.3.3 Variables para cliniques : Tous les patients inclus ont bénéficié d'un écho-Doppler veineux des membres inférieurs à la recherche d'une thrombose veineuse profonde et d'un angioscanner thoracique à la recherche d'une embolie pulmonaire.
II.3.4 Therapeutic variables
The therapeutic management was done by different types of anticoagulants at a curative dose. The choice of molecules was made based on the severity of the disease and the patients' comorbidities.
II.3.4.1 Low molecular weight heparin (LOVENOX 60mg/0.6ml) at a dose of 100IU/kg/12h.
II.3.4.2 Anti vitamin K with a target INR between 2 and 3:
II.3.4.2.1 Acenocoumarol (Sintrom 4mg): Start with 1 cp/jr (3/4 for lean subjects), then adjust doses until the target INR is reached. Time of action 48 to 72 hours.
II.3.4.2.2 Fluidione (Previscan 20 mg): Start with 1 pc/day. Onset of action 36 to 72 hours.
II.3 4.2.3 Warfarin (Coumadin 5 mg): Start at 5 mg/day. Duration of action 36 to 72 hours.
II.3.4.3 Direct Oral Anticoagulants (DOAC): Their monitoring does not require INR control.
II.3.4.3.1 Rivaroxaban 15 and 20 mg: Start with 15 mg x 2/day for 3 weeks then at 20 mg/day.
II.3.4.3.2Apixaban 5 and 10 mg: start with 10 mg x 2/day for 7 then 5 mg x 2/day.
II.3.4.4 Fibrinolytics
Streptokinase
II.4 Echantillonnage
We have made an exhaustive recruitment of all hospitalized patients for
MTEV in the Cardiology service during the study period.
II.5 Management, data analysis, and ethical consideration
Patient participation was obtained after their consent. Anonymity was guaranteed and maintained. The analysis and data processing were carried out using EPI info software version 7.2.3 and Microsoft 365 for data entry, table and figure design. The references were generated by Zotero.
During the study period, 217 patients were hospitalized in the cardiology department, including 31 cases of MVTE, a prevalence of 14.29%. It was 11 men and 20 women, a sex ratio of 0.64. The average age of our patients was 52.31 years 18.84, with extremes of 20 and 80 years. The most affected age group was that of 40-45 years old, which involved 14 patients, or 45, 16%. (Table I)
| Variables | size | Pourcentage |
| Age | ||
| 20-55 | 18 | 58,1 |
| 56 - 80 | 13 | 41,9 |
| Average Age | 52,31 ±18,84 | Extreme 20 and 80 years |
| Gender | ||
| Masculin | 20 | 64,52 |
| Female | 11 | 35,48 |
Table I: Presentation of patients according to epidemiological data
Risk factors for MVTE were dominated by oral contraception (16.12%), followed by prolonged bed rest. (table II).
| Risk Factors | Size | Percentage |
| Prolonged bed rest | 2 | 6,45 |
| Oral Contraception | 5 | 16,12 |
| History of Thrombosis | 2 | 6,45 |
| Superior Journey 6H | 1 | 3,23 |
| overweight | 1 | 3,23 |
| Immobilization Plastered | 1 | 3,23 |
| Not Found | 19 | 61,29 |
Table II: Presentation of patients according to risk factors.
The symptomatology of pulmonary embolism was dominated by dyspnea and chest pain at fair proportions (70.96%), while that of DVT was dominated by unilateral painful swelling (29%). (Table III)
| symptoms | Size | Percentage |
| Pain +Edema at LM | 9 | 29,03 |
| chest pain | 22 | 70,96 |
| dyspnoea | 22 | 70,96 |
| Hémoptysie | 1 | 3,22 |
| cough | 18 | 58,06 |
| Fièvre | 1 | 3,22 |
| Tumefaction at the LM | 9 | 29,03 |
| others | 3 | 9,67 |
Table I: Presentation of patients according to symptoms.
Isolated pulmonary embolism was found in 3 patients (9.68%), DVT in 7 patients (22.58%) and the association of the two [2] pathologies in 21 patients (67.74%). Bilateral proximal pulmonary embolism was found in 54.54% of patients. DVT was more localized at the level of the vein, such as (50%). (Table IV)
| CLINICAL ENTTIES | Frequency | Percentage |
| Pulmonary Embolism | 21 | 67,74 |
| TVP | 7 | 22,58 |
| EP + TVP | 3 | 9,68 |
| Location of the EP | Frequency | Percentage |
| Bilateral Proximal Pulmonary Embolism | 12 | 54,54 |
| Unilateral Proximal Pulmonary Embolism | 2 | 9,09 |
Bilateral Distal Pulmonary Embolism | 10 | 45,45 |
| distal unilateral pulmonary embolism | 2 | 9,09 |
| Location of the TVP | Frequency | Percentage |
| Common Femoral Vein | 5 | 50,00 |
| Femoral Vein Shallow | 3 | 30,00 |
| popliteal Vein | 2 | 20,00 |
Table IV: Presentation of patients according to the results of the venous Doppler echo of the lower limbs and the thoracic angioscanner.
Therapeutically, among the 21 cases of pulmonary embolism, 3 patients underwent thrombolysis and the other 18 were treated with oral anticoagulation. VKAs were the most used (45.16%). (Table V) The evolution was favorable in 90% of cases. (table VI)
| Treatment | Size | Percentage |
| Apixaban | 9 | 29.03 |
| Rivaroxaban | 8 | 25.81 |
| Acénocumorol | 14 | 45.16 |
| enoxaparin | 14 | 45.16 |
| thrombolysis | 3 | 9.68 |
Table V: Presentation of patients according to the treatment received.
| Evolution | frequency | Pourcentage |
| favourable | 28 | 90,32 |
| Complication | 3 | 9,67 |
| death | 0 | 0 |
| Total | 31 | 31 |
Table VI: Presentation of patients according to short-term evolution.
In this work, we encountered difficulties related to the performance of certain paraclinical examinations, notably the thoracic angioscanner, because it is done at a high cost while the population is poor, mostly without insurance.
Nevertheless, this work allows us to have statistics on this health phenomenon and informs us about the use of anti-thrombotics in the treatment of pulmonary embolism.
Our study shows a hospital prevalence of VTE at the Ignace Deen National Hospital at 14, 29%. This figure is much higher than several data from the literature whose prevalence varies between 1.1 to 3% [1,4,6,7]. This variability in the prevalences of the VTE could result from the difference in the populations studied. These differences may be related to socio-demographic, dietary or genetic factors. They could also be linked to methodological differences used for diagnosis. The means of exploration differ from one region to another, due to a defect in the technical platform and limited access to care.
This high prevalence, in our context, would be justified by the lack of preventive measures for MVTE, particularly in post-surgery.
The female predominance (64.5%) observed in our study corroborates that described in the literature and would probably be related to the existence of factors specific to female sex such as contraception, pregnancy, and postpartum [1,6,7]. On the other hand, in the work of Baye et al. in Senegal, it is men who predominated with a sex ratio of 1.45 in favor of men [7].
We found in our series an average age of 52.31 years 18.84. This result is close to those of Owono in Cameroon and Diallo whose average age of the patients studied is 50.61 years 25 and 52.7 years 14 respectively [6.8]. On the other hand, this data is higher than that found by Diallo et al. In Mali, with an average age of 43 years 9 [11].
Oral contraception (16.12%) and prolonged bed rest (6.45%) are the most common risk factors for MVTE in our observation. However, no risk factors were found in a large proportion of the cohort (61.29%). In the study conducted by Rachi et al., The most common risk factors were prolonged immobilisation (24%) and recent surgery (10%); in this observation, etiologies were dominated by neoplasms (26%) [10]. On this issue of MVTE risk factors, there are ...
Clinically, no clinical sign is sensitive and specific enough to confirm or deny VTE. These clinical signs are integrated into scores (Wells or Geneva scores for the EP, Wells score for the DVT) which allow to estimate a priori clinical probability [13]. This clinical probability will allow to guide the realization of complementary examinations and to discuss the urgent introduction of a thrombotic treatment. Despite chest pain and dyspnea are major signs leading to the search for a pulmonary embolism, but they are also found in most cardio-respiratory pathologies [13]. These signs were found in high and fair proportions in our study, 70.96% respectively for chest pain and dyspnea.
In this work, the clinical scores combined with imaging allowed us to diagnose 3 cases of isolated pulmonary embolism (9.68%), 7 cases of isolated DVT (22.58%) and 21 cases of association of these two [2] pathologies (67.74%). These results are comparable to those of Bell WR et al. who, in a study conducted in the United States, had found 48% isolated TVP and 23% EP with or without TVP [14].
Therapeutically, the management of pulmonary embolism is generally in a hospital setting, while DVT can be treated as an outpatient. Anticoagulant treatment is done parenterally (heparin, thrombotic) and orally (AVK and AOD ,16). The risk of thromboembolic recurrence is low when the initial episode is caused by a major reversible risk factor; in this case, a short treatment of three months is sufficient [17]. In patients who have developed an idiopathic pulmonary embolism (no apparent risk factor) or in association with a persistent risk factor, such as cancer, the risk of recurrence is high; prolonged treatment for at least six months is then necessary [16]. Following this initial analysis, the duration of treatment is then modulated by the presence or absence of certain additional factors (presence of major thrombophilia, persistence of pulmonary arterial hypertension or severity of the episode) [5,18,19]. In our work, all patients were hospitalized, 3 patients benefited from thrombolysis and the other 18 were treated with oral anticoagulation. VKAs were the most used (45.16%).
The evolution was favorable in 90% of the cases of our series, this result is close to that obtained by Maiga and her colleagues in Mali who noted a favorable evolution of VTE under treatment in 84% of the cases [20]. Indeed, the evolution of VTE is good if the management is early and diligent, even before the paraclinical confirmation with a good therapeutic observation
Thromboembolic venous disease is a frequent and fatal pathology. The diagnosis is made by an algorithm where the clinical arguments are grouped on scores and completed by biology or imaging. The treatment of the pathology is done by curative dose anticoagulants for a minimum duration of 3 months. The causes being multifactorial, the availability of more efficient biological laboratories would be of great diagnostic use.
the authors declare no conflict of interest.
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I would like to express my sincere gratitude for the support and efficiency provided by the editorial office throughout the publication process of my article, “Delayed Vulvar Metastases from Rectal Carcinoma: A Case Report.” I greatly appreciate the assistance and guidance I received from your team, which made the entire process smooth and efficient. The peer review process was thorough and constructive, contributing to the overall quality of the final article. I am very grateful for the high level of professionalism and commitment shown by the editorial staff, and I look forward to maintaining a long-term collaboration with the International Journal of Clinical Case Reports and Reviews.
To Dear Erin Aust, I would like to express my heartfelt appreciation for the opportunity to have my work published in this esteemed journal. The entire publication process was smooth and well-organized, and I am extremely satisfied with the final result. The Editorial Team demonstrated the utmost professionalism, providing prompt and insightful feedback throughout the review process. Their clear communication and constructive suggestions were invaluable in enhancing my manuscript, and their meticulous attention to detail and dedication to quality are truly commendable. Additionally, the support from the Editorial Office was exceptional. From the initial submission to the final publication, I was guided through every step of the process with great care and professionalism. The team's responsiveness and assistance made the entire experience both easy and stress-free. I am also deeply impressed by the quality and reputation of the journal. It is an honor to have my research featured in such a respected publication, and I am confident that it will make a meaningful contribution to the field.
"I am grateful for the opportunity of contributing to [International Journal of Clinical Case Reports and Reviews] and for the rigorous review process that enhances the quality of research published in your esteemed journal. I sincerely appreciate the time and effort of your team who have dedicatedly helped me in improvising changes and modifying my manuscript. The insightful comments and constructive feedback provided have been invaluable in refining and strengthening my work".
I thank the ‘Journal of Clinical Research and Reports’ for accepting this article for publication. This is a rigorously peer reviewed journal which is on all major global scientific data bases. I note the review process was prompt, thorough and professionally critical. It gave us an insight into a number of important scientific/statistical issues. The review prompted us to review the relevant literature again and look at the limitations of the study. The peer reviewers were open, clear in the instructions and the editorial team was very prompt in their communication. This journal certainly publishes quality research articles. I would recommend the journal for any future publications.
Dear Jessica Magne, with gratitude for the joint work. Fast process of receiving and processing the submitted scientific materials in “Clinical Cardiology and Cardiovascular Interventions”. High level of competence of the editors with clear and correct recommendations and ideas for enriching the article.
We found the peer review process quick and positive in its input. The support from the editorial officer has been very agile, always with the intention of improving the article and taking into account our subsequent corrections.
My article, titled 'No Way Out of the Smartphone Epidemic Without Considering the Insights of Brain Research,' has been republished in the International Journal of Clinical Case Reports and Reviews. The review process was seamless and professional, with the editors being both friendly and supportive. I am deeply grateful for their efforts.
To Dear Erin Aust – Editorial Coordinator of Journal of General Medicine and Clinical Practice! I declare that I am absolutely satisfied with your work carried out with great competence in following the manuscript during the various stages from its receipt, during the revision process to the final acceptance for publication. Thank Prof. Elvira Farina
Dear Jessica, and the super professional team of the ‘Clinical Cardiology and Cardiovascular Interventions’ I am sincerely grateful to the coordinated work of the journal team for the no problem with the submission of my manuscript: “Cardiometabolic Disorders in A Pregnant Woman with Severe Preeclampsia on the Background of Morbid Obesity (Case Report).” The review process by 5 experts was fast, and the comments were professional, which made it more specific and academic, and the process of publication and presentation of the article was excellent. I recommend that my colleagues publish articles in this journal, and I am interested in further scientific cooperation. Sincerely and best wishes, Dr. Oleg Golyanovskiy.
Dear Ashley Rosa, Editorial Coordinator of the journal - Psychology and Mental Health Care. " The process of obtaining publication of my article in the Psychology and Mental Health Journal was positive in all areas. The peer review process resulted in a number of valuable comments, the editorial process was collaborative and timely, and the quality of this journal has been quickly noticed, resulting in alternative journals contacting me to publish with them." Warm regards, Susan Anne Smith, PhD. Australian Breastfeeding Association.
Dear Jessica Magne, Editorial Coordinator, Clinical Cardiology and Cardiovascular Interventions, Auctores Publishing LLC. I appreciate the journal (JCCI) editorial office support, the entire team leads were always ready to help, not only on technical front but also on thorough process. Also, I should thank dear reviewers’ attention to detail and creative approach to teach me and bring new insights by their comments. Surely, more discussions and introduction of other hemodynamic devices would provide better prevention and management of shock states. Your efforts and dedication in presenting educational materials in this journal are commendable. Best wishes from, Farahnaz Fallahian.
Dear Maria Emerson, Editorial Coordinator, International Journal of Clinical Case Reports and Reviews, Auctores Publishing LLC. I am delighted to have published our manuscript, "Acute Colonic Pseudo-Obstruction (ACPO): A rare but serious complication following caesarean section." I want to thank the editorial team, especially Maria Emerson, for their prompt review of the manuscript, quick responses to queries, and overall support. Yours sincerely Dr. Victor Olagundoye.
Dear Ashley Rosa, Editorial Coordinator, International Journal of Clinical Case Reports and Reviews. Many thanks for publishing this manuscript after I lost confidence the editors were most helpful, more than other journals Best wishes from, Susan Anne Smith, PhD. Australian Breastfeeding Association.
Dear Agrippa Hilda, Editorial Coordinator, Journal of Neuroscience and Neurological Surgery. The entire process including article submission, review, revision, and publication was extremely easy. The journal editor was prompt and helpful, and the reviewers contributed to the quality of the paper. Thank you so much! Eric Nussbaum, MD
Dr Hala Al Shaikh This is to acknowledge that the peer review process for the article ’ A Novel Gnrh1 Gene Mutation in Four Omani Male Siblings, Presentation and Management ’ sent to the International Journal of Clinical Case Reports and Reviews was quick and smooth. The editorial office was prompt with easy communication.
Dear Erin Aust, Editorial Coordinator, Journal of General Medicine and Clinical Practice. We are pleased to share our experience with the “Journal of General Medicine and Clinical Practice”, following the successful publication of our article. The peer review process was thorough and constructive, helping to improve the clarity and quality of the manuscript. We are especially thankful to Ms. Erin Aust, the Editorial Coordinator, for her prompt communication and continuous support throughout the process. Her professionalism ensured a smooth and efficient publication experience. The journal upholds high editorial standards, and we highly recommend it to fellow researchers seeking a credible platform for their work. Best wishes By, Dr. Rakhi Mishra.
Dear Jessica Magne, Editorial Coordinator, Clinical Cardiology and Cardiovascular Interventions, Auctores Publishing LLC. The peer review process of the journal of Clinical Cardiology and Cardiovascular Interventions was excellent and fast, as was the support of the editorial office and the quality of the journal. Kind regards Walter F. Riesen Prof. Dr. Dr. h.c. Walter F. Riesen.
Dear Ashley Rosa, Editorial Coordinator, International Journal of Clinical Case Reports and Reviews, Auctores Publishing LLC. Thank you for publishing our article, Exploring Clozapine's Efficacy in Managing Aggression: A Multiple Single-Case Study in Forensic Psychiatry in the international journal of clinical case reports and reviews. We found the peer review process very professional and efficient. The comments were constructive, and the whole process was efficient. On behalf of the co-authors, I would like to thank you for publishing this article. With regards, Dr. Jelle R. Lettinga.
Dear Clarissa Eric, Editorial Coordinator, Journal of Clinical Case Reports and Studies, I would like to express my deep admiration for the exceptional professionalism demonstrated by your journal. I am thoroughly impressed by the speed of the editorial process, the substantive and insightful reviews, and the meticulous preparation of the manuscript for publication. Additionally, I greatly appreciate the courteous and immediate responses from your editorial office to all my inquiries. Best Regards, Dariusz Ziora
Dear Chrystine Mejia, Editorial Coordinator, Journal of Neurodegeneration and Neurorehabilitation, Auctores Publishing LLC, We would like to thank the editorial team for the smooth and high-quality communication leading up to the publication of our article in the Journal of Neurodegeneration and Neurorehabilitation. The reviewers have extensive knowledge in the field, and their relevant questions helped to add value to our publication. Kind regards, Dr. Ravi Shrivastava.
Dear Clarissa Eric, Editorial Coordinator, Journal of Clinical Case Reports and Studies, Auctores Publishing LLC, USA Office: +1-(302)-520-2644. I would like to express my sincere appreciation for the efficient and professional handling of my case report by the ‘Journal of Clinical Case Reports and Studies’. The peer review process was not only fast but also highly constructive—the reviewers’ comments were clear, relevant, and greatly helped me improve the quality and clarity of my manuscript. I also received excellent support from the editorial office throughout the process. Communication was smooth and timely, and I felt well guided at every stage, from submission to publication. The overall quality and rigor of the journal are truly commendable. I am pleased to have published my work with Journal of Clinical Case Reports and Studies, and I look forward to future opportunities for collaboration. Sincerely, Aline Tollet, UCLouvain.
Dear Ms. Mayra Duenas, Editorial Coordinator, International Journal of Clinical Case Reports and Reviews. “The International Journal of Clinical Case Reports and Reviews represented the “ideal house” to share with the research community a first experience with the use of the Simeox device for speech rehabilitation. High scientific reputation and attractive website communication were first determinants for the selection of this Journal, and the following submission process exceeded expectations: fast but highly professional peer review, great support by the editorial office, elegant graphic layout. Exactly what a dynamic research team - also composed by allied professionals - needs!" From, Chiara Beccaluva, PT - Italy.
Dear Maria Emerson, Editorial Coordinator, we have deeply appreciated the professionalism demonstrated by the International Journal of Clinical Case Reports and Reviews. The reviewers have extensive knowledge of our field and have been very efficient and fast in supporting the process. I am really looking forward to further collaboration. Thanks. Best regards, Dr. Claudio Ligresti
Dear Chrystine Mejia, Editorial Coordinator, Journal of Neurodegeneration and Neurorehabilitation. “The peer review process was efficient and constructive, and the editorial office provided excellent communication and support throughout. The journal ensures scientific rigor and high editorial standards, while also offering a smooth and timely publication process. We sincerely appreciate the work of the editorial team in facilitating the dissemination of innovative approaches such as the Bonori Method.” Best regards, Dr. Matteo Bonori.
I recommend without hesitation submitting relevant papers on medical decision making to the International Journal of Clinical Case Reports and Reviews. I am very grateful to the editorial staff. Maria Emerson was a pleasure to communicate with. The time from submission to publication was an extremely short 3 weeks. The editorial staff submitted the paper to three reviewers. Two of the reviewers commented positively on the value of publishing the paper. The editorial staff quickly recognized the third reviewer’s comments as an unjust attempt to reject the paper. I revised the paper as recommended by the first two reviewers.
Dear Maria Emerson, Editorial Coordinator, Journal of Clinical Research and Reports. Thank you for publishing our case report: "Clinical Case of Effective Fetal Stem Cells Treatment in a Patient with Autism Spectrum Disorder" within the "Journal of Clinical Research and Reports" being submitted by the team of EmCell doctors from Kyiv, Ukraine. We much appreciate a professional and transparent peer-review process from Auctores. All research Doctors are so grateful to your Editorial Office and Auctores Publishing support! I amiably wish our article publication maintained a top quality of your International Scientific Journal. My best wishes for a prosperity of the Journal of Clinical Research and Reports. Hope our scientific relationship and cooperation will remain long lasting. Thank you very much indeed. Kind regards, Dr. Andriy Sinelnyk Cell Therapy Center EmCell
Dear Editorial Team, Clinical Cardiology and Cardiovascular Interventions. It was truly a rewarding experience to work with the journal “Clinical Cardiology and Cardiovascular Interventions”. The peer review process was insightful and encouraging, helping us refine our work to a higher standard. The editorial office offered exceptional support with prompt and thoughtful communication. I highly value the journal’s role in promoting scientific advancement and am honored to be part of it. Best regards, Meng-Jou Lee, MD, Department of Anesthesiology, National Taiwan University Hospital.
Dear Editorial Team, Journal-Clinical Cardiology and Cardiovascular Interventions, “Publishing my article with Clinical Cardiology and Cardiovascular Interventions has been a highly positive experience. The peer-review process was rigorous yet supportive, offering valuable feedback that strengthened my work. The editorial team demonstrated exceptional professionalism, prompt communication, and a genuine commitment to maintaining the highest scientific standards. I am very pleased with the publication quality and proud to be associated with such a reputable journal.” Warm regards, Dr. Mahmoud Kamal Moustafa Ahmed
Dear Maria Emerson, Editorial Coordinator of ‘International Journal of Clinical Case Reports and Reviews’, I appreciate the opportunity to publish my article with your journal. The editorial office provided clear communication during the submission and review process, and I found the overall experience professional and constructive. Best regards, Elena Salvatore.
Dear Mayra Duenas, Editorial Coordinator of ‘International Journal of Clinical Case Reports and Reviews Herewith I confirm an optimal peer review process and a great support of the editorial office of the present journal
Dear Editorial Team, Clinical Cardiology and Cardiovascular Interventions. I am really grateful for the peers review; their feedback gave me the opportunity to reflect on the message and impact of my work and to ameliorate the article. The editors did a great job in addition by encouraging me to continue with the process of publishing.
Dear Cecilia Lilly, Editorial Coordinator, Endocrinology and Disorders, Thank you so much for your quick response regarding reviewing and all process till publishing our manuscript entitled: Prevalence of Pre-Diabetes and its Associated Risk Factors Among Nile College Students, Sudan. Best regards, Dr Mamoun Magzoub.
International Journal of Clinical Case Reports and Reviews is a high quality journal that has a clear and concise submission process. The peer review process was comprehensive and constructive. Support from the editorial office was excellent, since the administrative staff were responsive. The journal provides a fast and timely publication timeline.
Dear Maria Emerson, Editorial Coordinator of International Journal of Clinical Case Reports and Reviews, What distinguishes International Journal of Clinical Case Report and Review is not only the scientific rigor of its publications, but the intellectual climate in which research is evaluated. The submission process is refreshingly free of unnecessary formal barriers and bureaucratic rituals that often complicate academic publishing without adding real value. The peer-review system is demanding yet constructive, guided by genuine scientific dialogue rather than hierarchical or authoritarian attitudes. Reviewers act as collaborators in improving the manuscript, not as gatekeepers imposing arbitrary standards. This journal offers a rare balance: high methodological standards combined with a respectful, transparent, and supportive editorial approach. In an era where publishing can feel more burdensome than research itself, this platform restores the original purpose of peer review — to refine ideas, not to obstruct them Prof. Perlat Kapisyzi, FCCP PULMONOLOGIST AND THORACIC IMAGING.
Dear Grace Pierce, International Journal of Clinical Case Reports and Reviews I appreciate the opportunity to review for Auctore Journal, as the overall editorial process was smooth, transparent and professionally managed. This journal maintains high scientific standards and ensures timely communications with authors, which is truly commendable. I would like to express my special thanks to editor Grace Pierce for his constant guidance, promt responses, and supportive coordination throughout the review process. I am also greatful to Eleanor Bailey from the finance department for her clear communication and efficient handling of all administrative matters. Overall, my experience with Auctore Journal has been highly positive and rewarding. Best regards, Sabita sinha
Dear Mayra Duenas, Editorial Coordinator of the journal IJCCR, I write here a little on my experience as an author submitting to the International Journal of Clinical Case Reports and Reviews (IJCCR). This was my first submission to IJCCR and my manuscript was inherently an outsider’s effort. It attempted to broadly identify and then make some sense of life’s under-appreciated mysteries. I initially had responded to a request for possible submissions. I then contacted IJCCR with a tentative topic for a manuscript. They quickly got back with an approval for the submission, but with a particular requirement that it be medically relevant. I then put together a manuscript and submitted it. After the usual back-and-forth over forms and formality, the manuscript was sent off for reviews. Within 2 weeks I got back 4 reviews which were both helpful and also surprising. Surprising in that the topic was somewhat foreign to medical literature. My subsequent updates in response to the reviewer comments went smoothly and in short order I had a series of proofs to evaluate. All in all, the whole publication process seemed outstanding. It was both helpful in terms of the paper’s content and also in terms of its efficient and friendly communications. Thank you all very much. Sincerely, Ted Christopher, Rochester, NY.
