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Research Article | DOI: https://doi.org/10.31579/2690-1919/605
1Clinical professor, University of Hawaii, John A. Burns School of Medicine 55 S. Kukui St. C-109 Honolulu, Hawaii 96813, USA.
2Medical Student, University of Hawaii, John A. Burns School of Medicine, USA.
*Corresponding Author: Ming Chen, Clinical professor, University of Hawaii, John A. Burns School of Medicine 55 S. Kukui St. C-109 Honolulu, Hawaii 96813, USA.
Citation: Ming Chen, Emily Kang, (2025), Long Term Efficacy and Safety of Endocyclophotocoagulation Combined with Phacoemulsification in Asian Eyes- A Case Series Study, J Clinical Research and Reports, 23(1); DOI:10.31579/2690-1919/605
Copyright: © 2025, Ming Chen. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Received: 17 December 2025 | Accepted: 22 December 2025 | Published: 05 January 2026
Keywords: asian; cataract; endocyclophotocoagulation; glaucoma; phacoemulsification
Purposes: A case series study of the long-term efficacy and safety of Endocyclophotocoagulation combined with phacoemulsification on Asian eyes with cataract and glaucoma.
Significance: Cataract surgery alone can reduce intraocular pressure. However, many confirmed glaucoma cases withcataract that just perform cataract surgery alone cannot lower IOP enough to target pressure. Many Asian glaucomatic eyes have narrow angle component to inhibit aqueous out-flow, while angle procedures will be unable to perform. Combining cataract surgery with Endocyclophotocoagulation was reported can further reducing intraocular pressure. This study, to our knowledge, may be represents the longest follow-up of Endocyclophotocoagulation combined with phacoemulsification in Asian eyes with glaucoma.
Method: A random chart review of 41 Asian eyes of 41 patients with various types and severity of glaucoma and cataract that underwent Endocyclophotocoagulation combined with phacoemulsification from 2012 to 2024 with various period of follow up by a single surgeon at a single center with a single laser machine In Honolulu, USA. Preoperative and postoperative mean intraocular pressures (IOP) were compared.
Results: No complications related to Endocyclophotocoagulation were reported in all of the 41 eyes. IOP were checked by a single calibrated automatic non-contact tonometry two weeks before and two weeks after surgery. In order to effectively control various severities of glaucoma depending on the vision, visual field and optic nerve of the eyes, a target intraocular pressure has to be established and reached. Therefore, 44% of eyes needed eye medication and 40% need eye needed medication and further procedures after the surgery. 17% were free from medication and procedure to be on target IOP. Comparison showed those severe cases that needed medication and procedures pre-op and post -op had Endocyclophotocoagulation demonstrated statistically significant lower mean IOP.
Pre-op: 18.5(5.2); post-op: 14.9(3.0)
Pre-op:19.1 (5.7); post-op:15.0 (2.8)
Pre-op: 19.1(5.1); post-op:15.5 (3.3)
Pre-op:15.7(3.4); post-op:13.7(3.7)
Conclusion: Endocyclophotocoagulation combine with phacoemulsification can be safe and effective for Asian eyes with narrow angle glaucoma and cataract.
Glaucoma is a leading cause of blindness worldwide. Various medications, laser, and surgical procedures are available to control intraocular pressure (IOP) within target ranges to prevent further disease progression. Glaucoma is often associated with cataracts as part of the aging process, especially for the older Asian population. While cataract surgery alone can reduce IOP in some cases, recent studies show that combining phacoemulsification with minimally invasive glaucoma surgeries (MIGS) can further lower IOP. This can reduce or eliminate the need for glaucoma medications or further surgical interventions. In addition, the combined approach can improve compliance, lower treatment costs, and minimize side-effects associated with long-term glaucoma medication use.
One type of the MIGS to treat moderate-to-severe glaucoma is the Cyclodestructive procedure, which reduces aqueous humor production through targeted ciliary body ablation. [1-3], Among them, Endocyclophotocoagulation (ECP)allows direct visualization of the ciliary processes with precise laser application and demonstrated superior safety compared to TransScleraCyclophotoCoagulation (TSCPC) [4-7]. First described by Uram in 1992, ECP delivers predictable outcomes and favorable safety profile by minimizing damage to surrounding tissues and sclera, making it suitable for a wide range of patients [8].
Previous studies have demonstrated the safety and efficacy of ECP combined with phacoemulsification [9, 10]. However, most prior studies were short-term and focused on refractory glaucoma, open-angle glaucoma, or intractable neovascular glaucoma, often with limited Asian populations [ 11, 12]. In Bolek’s study, for instance, only 7.9 percent of cases involved narrow-angle glaucoma [13].
Since Asian patients are more likely to present with narrow or partial narrow angle glaucoma with concurrent cataract, focusing on this particular population is paramount. Moreover, because the non-pigmented ciliary epithelium can regenerate after laser ablation, long-term studies are necessary to confirm sustained efficacy [16,18].
Moreover, narrow-angle glaucoma is not feasible with Selective Laser Trabeculoplasty (SLT) and angle-based implants. In such cases, ECP is especially advantageous as it may serve as a safe, effective, and economical treatment option, particularly performed alongside phacoemulsification. This combined procedure requires only a single incision and may therefore be especially advantageous. In the era of interventional glaucoma treatment to reduce medication, combining ECP with phacoemulsification certainly should be considered on most glaucoma patients with cataract [16,18].
This study reviews over 12 years of consecutive cases of ECP combined with phacoemulsification performed in Asian eyes with glaucoma, with follow-up periods ranging from 3 to 12 years.
This is a randomized case series study of 41 consecutive Asian eyes from 41 patients who underwent Endocyclophotocoagulation (ECP) combined with phacoemulsification cataract surgery between 2012 and 2024. All procedures were performed by a single surgeon (Dr. Ming Chen) at a single surgical center (SugicalSuite) in Honolulu, Hawaii, using a single ECP laser system.
Patients were between 58 to 88 years old (mean = 74 years), consisting of 18 males and 23 females. All patients (n = 41) were Asian with cataracts and glaucoma of varying severity. All consecutive patients undergoing ECP combined with phacoemulsification for cataract and glaucoma, regardless of stage and the majority of cases were narrow angle glaucoma (68.20%) were included to be reviewed.
The data collected were preoperative and postoperative mean intraocular pressure (IOP), ranging from 3 to 12 years (mean 6.4 years) of follow-up periods. Further data collected were the need for postoperative glaucoma medication and additional glaucoma procedures.
Phacoemulsification was done by Dr. Ming Chen with all cases under topical anesthesia. After cataract extraction and implantation of intraocular lens, the preservative free lidocaine was injected into the posterior chamber. Then, viscoelastic was used to fill and expand the space between the implant and iris to expose the ciliary process. An ECP probe (EndoOptiks, Beaver-Visitec, Waltham, MA, USA) was inserted into the posterior chamber and aimed at the ciliary processes under illumination. Lastly, diode laser was delivered to 200° to 250° of the ciliary processes until whitening of ciliary tissue was observed. The laser was set at 200mW to 250mWand and adjusted as needed.
| Cataract Type | % of Eyes |
| Age-related nuclear cataract | 82.90% |
| Cortical cataract | 4.90% |
| Combined form | 4.90% |
| Posterior subcapsular cataract | 2.40% |
| Cortical senile cataract | 2.40% |
| Morgagnian cataract | 2.40% |
| Mature cataract | 2.40% |
Table 1: Pre-operative Cataract Types
| Glaucoma Type | % of Eyes |
| Chronic angle-closure glaucoma | 48.70% |
| Primary open-angle glaucoma | 43.90% |
| Intermittent angle-closure glaucoma | 19.50% |
| Low-tension glaucoma | 9.80% |
| Hypersecretion glaucoma | 4.90% |
| Psudoexfoliation glaucoma | 2.40% |
| Severe-stage glaucoma | 2.40% |
| Capsular glaucoma with psudoexfoliation | 2.40% |
Table 2: Glaucoma Types
Other vision related diagnosis included were leukoma, pterygium, cystoid macular degeneration, dry eye disease, age-related macular degeneration, ptosis, and macula puckering.
Vision data were not reported due to vision can be variable by above reasons and can be confounding.
IOP measurements were recorded before and after treatment. Analyses included the overall cohort of 41 patients who underwent ECP with phacoemulsification (ECP + Phaco, All), along with three mutually exclusive subgroups based on postoperative treatment needs: [1], patients requiring medications only (ECP + Phaco + Meds) [2] patients requiring both medications and additional glaucoma procedures (ECP + Phaco + Meds + Surg), and [3], patients requiring no further treatment (ECP + Phaco Only).
Descriptive statistics (mean, standard deviation, and mean difference) were computed for IOP before and after intervention in each group. Paired t-tests were used to assess the significance of within-group changes in IOP. A two-sided p-value < 0>
A total of 41 eyes underwent Endocyclophotocoagulation (ECP) combined with phacoemulsification. There were no complications related to ECP in all 41 eyes. Postoperatively, some patients required additional treatments to achieve target IOP. Among these patients, 18 required further treatment with IOP-lowering medications (44%), 16 required both medications and additional glaucoma procedures (40%), and 7 did not need any further treatment beyond the initial combined procedure (17%).
Pre-op: 18.5 (5.2); post-op: 14.9 (3.0); P< 0>
Pre-op: 19.1 (5.7); post-op: 15.0 (2.8); P = 0.009
Pre-op: 19.1 (5.1); post-op: 15.5 (3.3); P = 0.025
Pre-op:15.7 (3.4); post-op:13.7 (3.7); P< 0>
There was a statistically significant decrease in IOP post ECP combined with phacoemulsification in all groups. Seventeen percent of patients remained free from any medication or additional glaucoma procedures postoperatively.
Overall IOP Trends
Figure 1 shows box plots of intraocular pressure (IOP) before and after intervention for the overall cohort (n = 41) and the three mutually exclusive postoperative subgroups. All groups demonstrated significant reductions in IOP, with p-values annotated on the figure.
Figure 1: Box plot of IOP before vs. after for overall cohort and Subgroups
| Group | Mean IOP Before (SD) | Mean IOP After (SD) | Mean Diff (SD) | 95% CI | p-value |
| ECP + Phaco, All | 18.5 (5.2) | 14.9 (3.0) | -3.6 (5.3) | −5.25, −1.92 | < 0> |
| ECP + Phaco + Meds | 19.1 (5.7) | 15.0 (2.8) | -4.1 (5.9) | −7.07, −1.15 | 0.009 |
| ECP + Phaco + Meds + Surg | 19.1 (5.1) | 15.5 (3.3) | -3.6 (5.7) | −6.60, −0.52 | 0.025 |
| ECP + Phaco Only | 15.7 (3.4) | 13.7 (3.7) | -2.0 (0.8) | −2.76, −1.24 | < 0> |
Table 3: Descriptive Statistics and Paired Comparisons
Individual Patient Trajectories
Figure 2 presents patient-level IOP trajectories across the overall cohort and the three postoperative outcome subgroups. The ECP + Phaco Only group showed consistently tight responses, while greater variability was observed in patients who required medications or additional surgery.
Figure 2: Individual IOP Trajectories Before and After Intervention
Secondary Outcomes
Vision for subjects consisted of preoperative 20/30 to count finger and postoperative 20/20 to count finger. However, it is important to note that there were other ocular pathologies that may affect vision outcomes.
Interpretations
All four groups showed a statistically significant reduction in IOP following intervention. In the overall cohort (ECP + Phaco, All), mean IOP decreased by 3.6 mmHg with a 95% confidence interval of −5.25 to −1.92 (p< 0>
The subgroup that required additional medications (ECP + Phaco + Meds) showed the largest mean reduction of 4.1 mmHg (95% CI: −7.07 to −1.15; p = 0.009), suggesting that pharmacological intervention post-surgery provided additional benefit in IOP control.
Patients who required both medications and additional glaucoma procedures (ECP + Phaco + Meds + Surg) also experienced a significant mean IOP reduction of 3.6 mmHg (95% CI: −6.60 to −0.52; p = 0.025), though with slightly less precision as reflected in the wider confidence interval.
Interestingly, the group that required no further treatment beyond the initial procedure (ECP + Phaco Only) showed the most precise and consistent response, with a mean IOP reduction of 2.0 mmHg (95% CI: −2.76 to −1.24; p< 0>
These findings support the effectiveness of ECP combined with phacoemulsification in reducing IOP, with additional interventions tailored to patient needs providing further IOP control as necessary.
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My article, titled 'No Way Out of the Smartphone Epidemic Without Considering the Insights of Brain Research,' has been republished in the International Journal of Clinical Case Reports and Reviews. The review process was seamless and professional, with the editors being both friendly and supportive. I am deeply grateful for their efforts.
To Dear Erin Aust – Editorial Coordinator of Journal of General Medicine and Clinical Practice! I declare that I am absolutely satisfied with your work carried out with great competence in following the manuscript during the various stages from its receipt, during the revision process to the final acceptance for publication. Thank Prof. Elvira Farina
Dear Jessica, and the super professional team of the ‘Clinical Cardiology and Cardiovascular Interventions’ I am sincerely grateful to the coordinated work of the journal team for the no problem with the submission of my manuscript: “Cardiometabolic Disorders in A Pregnant Woman with Severe Preeclampsia on the Background of Morbid Obesity (Case Report).” The review process by 5 experts was fast, and the comments were professional, which made it more specific and academic, and the process of publication and presentation of the article was excellent. I recommend that my colleagues publish articles in this journal, and I am interested in further scientific cooperation. Sincerely and best wishes, Dr. Oleg Golyanovskiy.
Dear Ashley Rosa, Editorial Coordinator of the journal - Psychology and Mental Health Care. " The process of obtaining publication of my article in the Psychology and Mental Health Journal was positive in all areas. The peer review process resulted in a number of valuable comments, the editorial process was collaborative and timely, and the quality of this journal has been quickly noticed, resulting in alternative journals contacting me to publish with them." Warm regards, Susan Anne Smith, PhD. Australian Breastfeeding Association.
Dear Jessica Magne, Editorial Coordinator, Clinical Cardiology and Cardiovascular Interventions, Auctores Publishing LLC. I appreciate the journal (JCCI) editorial office support, the entire team leads were always ready to help, not only on technical front but also on thorough process. Also, I should thank dear reviewers’ attention to detail and creative approach to teach me and bring new insights by their comments. Surely, more discussions and introduction of other hemodynamic devices would provide better prevention and management of shock states. Your efforts and dedication in presenting educational materials in this journal are commendable. Best wishes from, Farahnaz Fallahian.
Dear Maria Emerson, Editorial Coordinator, International Journal of Clinical Case Reports and Reviews, Auctores Publishing LLC. I am delighted to have published our manuscript, "Acute Colonic Pseudo-Obstruction (ACPO): A rare but serious complication following caesarean section." I want to thank the editorial team, especially Maria Emerson, for their prompt review of the manuscript, quick responses to queries, and overall support. Yours sincerely Dr. Victor Olagundoye.
Dear Ashley Rosa, Editorial Coordinator, International Journal of Clinical Case Reports and Reviews. Many thanks for publishing this manuscript after I lost confidence the editors were most helpful, more than other journals Best wishes from, Susan Anne Smith, PhD. Australian Breastfeeding Association.
Dear Agrippa Hilda, Editorial Coordinator, Journal of Neuroscience and Neurological Surgery. The entire process including article submission, review, revision, and publication was extremely easy. The journal editor was prompt and helpful, and the reviewers contributed to the quality of the paper. Thank you so much! Eric Nussbaum, MD
Dr Hala Al Shaikh This is to acknowledge that the peer review process for the article ’ A Novel Gnrh1 Gene Mutation in Four Omani Male Siblings, Presentation and Management ’ sent to the International Journal of Clinical Case Reports and Reviews was quick and smooth. The editorial office was prompt with easy communication.
Dear Erin Aust, Editorial Coordinator, Journal of General Medicine and Clinical Practice. We are pleased to share our experience with the “Journal of General Medicine and Clinical Practice”, following the successful publication of our article. The peer review process was thorough and constructive, helping to improve the clarity and quality of the manuscript. We are especially thankful to Ms. Erin Aust, the Editorial Coordinator, for her prompt communication and continuous support throughout the process. Her professionalism ensured a smooth and efficient publication experience. The journal upholds high editorial standards, and we highly recommend it to fellow researchers seeking a credible platform for their work. Best wishes By, Dr. Rakhi Mishra.
Dear Jessica Magne, Editorial Coordinator, Clinical Cardiology and Cardiovascular Interventions, Auctores Publishing LLC. The peer review process of the journal of Clinical Cardiology and Cardiovascular Interventions was excellent and fast, as was the support of the editorial office and the quality of the journal. Kind regards Walter F. Riesen Prof. Dr. Dr. h.c. Walter F. Riesen.
Dear Ashley Rosa, Editorial Coordinator, International Journal of Clinical Case Reports and Reviews, Auctores Publishing LLC. Thank you for publishing our article, Exploring Clozapine's Efficacy in Managing Aggression: A Multiple Single-Case Study in Forensic Psychiatry in the international journal of clinical case reports and reviews. We found the peer review process very professional and efficient. The comments were constructive, and the whole process was efficient. On behalf of the co-authors, I would like to thank you for publishing this article. With regards, Dr. Jelle R. Lettinga.
Dear Clarissa Eric, Editorial Coordinator, Journal of Clinical Case Reports and Studies, I would like to express my deep admiration for the exceptional professionalism demonstrated by your journal. I am thoroughly impressed by the speed of the editorial process, the substantive and insightful reviews, and the meticulous preparation of the manuscript for publication. Additionally, I greatly appreciate the courteous and immediate responses from your editorial office to all my inquiries. Best Regards, Dariusz Ziora
Dear Chrystine Mejia, Editorial Coordinator, Journal of Neurodegeneration and Neurorehabilitation, Auctores Publishing LLC, We would like to thank the editorial team for the smooth and high-quality communication leading up to the publication of our article in the Journal of Neurodegeneration and Neurorehabilitation. The reviewers have extensive knowledge in the field, and their relevant questions helped to add value to our publication. Kind regards, Dr. Ravi Shrivastava.
Dear Clarissa Eric, Editorial Coordinator, Journal of Clinical Case Reports and Studies, Auctores Publishing LLC, USA Office: +1-(302)-520-2644. I would like to express my sincere appreciation for the efficient and professional handling of my case report by the ‘Journal of Clinical Case Reports and Studies’. The peer review process was not only fast but also highly constructive—the reviewers’ comments were clear, relevant, and greatly helped me improve the quality and clarity of my manuscript. I also received excellent support from the editorial office throughout the process. Communication was smooth and timely, and I felt well guided at every stage, from submission to publication. The overall quality and rigor of the journal are truly commendable. I am pleased to have published my work with Journal of Clinical Case Reports and Studies, and I look forward to future opportunities for collaboration. Sincerely, Aline Tollet, UCLouvain.
Dear Ms. Mayra Duenas, Editorial Coordinator, International Journal of Clinical Case Reports and Reviews. “The International Journal of Clinical Case Reports and Reviews represented the “ideal house” to share with the research community a first experience with the use of the Simeox device for speech rehabilitation. High scientific reputation and attractive website communication were first determinants for the selection of this Journal, and the following submission process exceeded expectations: fast but highly professional peer review, great support by the editorial office, elegant graphic layout. Exactly what a dynamic research team - also composed by allied professionals - needs!" From, Chiara Beccaluva, PT - Italy.
Dear Maria Emerson, Editorial Coordinator, we have deeply appreciated the professionalism demonstrated by the International Journal of Clinical Case Reports and Reviews. The reviewers have extensive knowledge of our field and have been very efficient and fast in supporting the process. I am really looking forward to further collaboration. Thanks. Best regards, Dr. Claudio Ligresti
Dear Chrystine Mejia, Editorial Coordinator, Journal of Neurodegeneration and Neurorehabilitation. “The peer review process was efficient and constructive, and the editorial office provided excellent communication and support throughout. The journal ensures scientific rigor and high editorial standards, while also offering a smooth and timely publication process. We sincerely appreciate the work of the editorial team in facilitating the dissemination of innovative approaches such as the Bonori Method.” Best regards, Dr. Matteo Bonori.
I recommend without hesitation submitting relevant papers on medical decision making to the International Journal of Clinical Case Reports and Reviews. I am very grateful to the editorial staff. Maria Emerson was a pleasure to communicate with. The time from submission to publication was an extremely short 3 weeks. The editorial staff submitted the paper to three reviewers. Two of the reviewers commented positively on the value of publishing the paper. The editorial staff quickly recognized the third reviewer’s comments as an unjust attempt to reject the paper. I revised the paper as recommended by the first two reviewers.
Dear Maria Emerson, Editorial Coordinator, Journal of Clinical Research and Reports. Thank you for publishing our case report: "Clinical Case of Effective Fetal Stem Cells Treatment in a Patient with Autism Spectrum Disorder" within the "Journal of Clinical Research and Reports" being submitted by the team of EmCell doctors from Kyiv, Ukraine. We much appreciate a professional and transparent peer-review process from Auctores. All research Doctors are so grateful to your Editorial Office and Auctores Publishing support! I amiably wish our article publication maintained a top quality of your International Scientific Journal. My best wishes for a prosperity of the Journal of Clinical Research and Reports. Hope our scientific relationship and cooperation will remain long lasting. Thank you very much indeed. Kind regards, Dr. Andriy Sinelnyk Cell Therapy Center EmCell
Dear Editorial Team, Clinical Cardiology and Cardiovascular Interventions. It was truly a rewarding experience to work with the journal “Clinical Cardiology and Cardiovascular Interventions”. The peer review process was insightful and encouraging, helping us refine our work to a higher standard. The editorial office offered exceptional support with prompt and thoughtful communication. I highly value the journal’s role in promoting scientific advancement and am honored to be part of it. Best regards, Meng-Jou Lee, MD, Department of Anesthesiology, National Taiwan University Hospital.
Dear Editorial Team, Journal-Clinical Cardiology and Cardiovascular Interventions, “Publishing my article with Clinical Cardiology and Cardiovascular Interventions has been a highly positive experience. The peer-review process was rigorous yet supportive, offering valuable feedback that strengthened my work. The editorial team demonstrated exceptional professionalism, prompt communication, and a genuine commitment to maintaining the highest scientific standards. I am very pleased with the publication quality and proud to be associated with such a reputable journal.” Warm regards, Dr. Mahmoud Kamal Moustafa Ahmed
Dear Maria Emerson, Editorial Coordinator of ‘International Journal of Clinical Case Reports and Reviews’, I appreciate the opportunity to publish my article with your journal. The editorial office provided clear communication during the submission and review process, and I found the overall experience professional and constructive. Best regards, Elena Salvatore.
Dear Mayra Duenas, Editorial Coordinator of ‘International Journal of Clinical Case Reports and Reviews Herewith I confirm an optimal peer review process and a great support of the editorial office of the present journal
Dear Editorial Team, Clinical Cardiology and Cardiovascular Interventions. I am really grateful for the peers review; their feedback gave me the opportunity to reflect on the message and impact of my work and to ameliorate the article. The editors did a great job in addition by encouraging me to continue with the process of publishing.
Dear Cecilia Lilly, Editorial Coordinator, Endocrinology and Disorders, Thank you so much for your quick response regarding reviewing and all process till publishing our manuscript entitled: Prevalence of Pre-Diabetes and its Associated Risk Factors Among Nile College Students, Sudan. Best regards, Dr Mamoun Magzoub.
International Journal of Clinical Case Reports and Reviews is a high quality journal that has a clear and concise submission process. The peer review process was comprehensive and constructive. Support from the editorial office was excellent, since the administrative staff were responsive. The journal provides a fast and timely publication timeline.
Dear Maria Emerson, Editorial Coordinator of International Journal of Clinical Case Reports and Reviews, What distinguishes International Journal of Clinical Case Report and Review is not only the scientific rigor of its publications, but the intellectual climate in which research is evaluated. The submission process is refreshingly free of unnecessary formal barriers and bureaucratic rituals that often complicate academic publishing without adding real value. The peer-review system is demanding yet constructive, guided by genuine scientific dialogue rather than hierarchical or authoritarian attitudes. Reviewers act as collaborators in improving the manuscript, not as gatekeepers imposing arbitrary standards. This journal offers a rare balance: high methodological standards combined with a respectful, transparent, and supportive editorial approach. In an era where publishing can feel more burdensome than research itself, this platform restores the original purpose of peer review — to refine ideas, not to obstruct them Prof. Perlat Kapisyzi, FCCP PULMONOLOGIST AND THORACIC IMAGING.
Dear Grace Pierce, International Journal of Clinical Case Reports and Reviews I appreciate the opportunity to review for Auctore Journal, as the overall editorial process was smooth, transparent and professionally managed. This journal maintains high scientific standards and ensures timely communications with authors, which is truly commendable. I would like to express my special thanks to editor Grace Pierce for his constant guidance, promt responses, and supportive coordination throughout the review process. I am also greatful to Eleanor Bailey from the finance department for her clear communication and efficient handling of all administrative matters. Overall, my experience with Auctore Journal has been highly positive and rewarding. Best regards, Sabita sinha
Dear Mayra Duenas, Editorial Coordinator of the journal IJCCR, I write here a little on my experience as an author submitting to the International Journal of Clinical Case Reports and Reviews (IJCCR). This was my first submission to IJCCR and my manuscript was inherently an outsider’s effort. It attempted to broadly identify and then make some sense of life’s under-appreciated mysteries. I initially had responded to a request for possible submissions. I then contacted IJCCR with a tentative topic for a manuscript. They quickly got back with an approval for the submission, but with a particular requirement that it be medically relevant. I then put together a manuscript and submitted it. After the usual back-and-forth over forms and formality, the manuscript was sent off for reviews. Within 2 weeks I got back 4 reviews which were both helpful and also surprising. Surprising in that the topic was somewhat foreign to medical literature. My subsequent updates in response to the reviewer comments went smoothly and in short order I had a series of proofs to evaluate. All in all, the whole publication process seemed outstanding. It was both helpful in terms of the paper’s content and also in terms of its efficient and friendly communications. Thank you all very much. Sincerely, Ted Christopher, Rochester, NY.
