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Research Article | DOI: https://doi.org/10.31579/2692-9562/153
1PhD Scholar, Amity University Rajasthan, Department of AIBAS, Jaipur.
2Associate Professor, SGT University, Department of AIBAS, Gurugram.
3Associate Professor, Amity University Haryana, Department Of ASLP, Gurugram.
4Professor, Vinayaka mission Higher Education, Pondicherry.
*Corresponding Author: Vijay Kumar., Associate Professor, SGT University, Department of AIBAS, Gurugram.
Citation: Arun K. Yadav, Ahsan A, Kumar V., Banik A, (2025), Impact of Over Six Months of Digital Hearing Aid Usage on Auditory Working Memory in Acquired Severe to Profound Hearing Loss, Journal of Clinical Otorhinolaryngology, 7(4); DOI:10.31579/2692-9562/153
Copyright: © 2025, Vijay Kumar. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Received: 24 November 2025 | Accepted: 05 December 2025 | Published: 15 December 2025
Keywords: auditory working memory; hearing aids; hearing loss; mental health; social skills; aural rehabilitation
Introduction
Hearing amplification devices providing ample auditory input that can help to decrease the cognitive strain caused by hearing loss. Depending on the kind and severity of hearing loss, using hearing aids has variable effects on auditory working memory. This study looked into the auditory working memory capacity after using hearing aids for more than six months.
Method
Sixty individuals of mean age of 53.4± 6.07 years with severe to profound hearing loss in the age range of 40-60 years participated. Out of which 30 individuals with mean age 53.5 ±6.7 were using digital hearing aids and another 30 individuals with mean age 53.3 ±5.4 years were not using hearing aid. Forward and backward digit span task (DST) and Mini-Mental Status Examination (MMSE) were investigated to estimate the auditory working memory capacity.
Results
Mean MMSE score of those individuals with severe to profound hearing loss (53.3±5.43) using (HAU) hearing aid (25.7±2.97) and individual not using (NHAU) hearing aid (22.1±5.11) were compared across each other. The result revealed that mean MMSE score of HAU was significantly higher than the mean score of NHAU. Mean DST (Forward, backward and total) score of HAU (6.40±1.47) was cosiderably higher than the mean score of NHAU (5.33±1.12).
Conclusion
Results showed that mean MMSE and DST score was higher in the HAU category but when compared across the gender no statistical differences was observed. The change in auditory working memory and other cognitive abilities were attributed to the usage duration of the hearing aids.
mini-mental state examination (hhia-s); digit span test (dst); hearing aid user (hau); non hearing aid user (nhau); quality of life (qol)
Hearing loss often impacts on physiological and sensory functions of the adults. Difficulty understanding speech in group and noisy environments are chief complaint reported by the hearing impaired adults. There is no clinical and surgical management that restores the normal hearing of patients with Sensorineural hearing loss. Only aural rehabilitation options are available such as amplification devices. The cognitive load brought on by hearing loss and its effects can be lessened with the use of amplification devices that provide sufficient auditory input. Auditory rehabilitation through digital devices (Such as Digital Hearing aid, Cochlear implant) in counteracting dementia [1, 2]. Aural rehabilitation can improve and reestablish the auditory perceptual abilities are necessary for spoken language and it also help to the central management of cognitive resources related with speech and Hearing processes. Hearing is an important variable to be considered in the assessment of cognitive function , and hearing loss is associated with incident dementia [3]. When the hearing loss is high in elderly than hearing loss is associated with falls and gait [3, 4]. The initial objective of this study was to determine whether hearing aid user experience of more than 6 months can enhance cognitive abilities individuals having severe to profound hearing loss. The cognitive abilities were assess using MMSE score and it was explore that whether MMSE score was change across the two age range which were 40-50 years and 51-60 years. Secondly whether auditory working memory capacity enhances after more than 6 months of hearing aid uses. Forward and backward digit span task were used to estimate the auditory working memory across the two age range which were 40-50 years and 51-60 years.
Participants:
60 Participants in this study age range from 40 to 60 years, with a mean age of 53.4± 6.07 years for those with significant hearing loss. 30 people, with an average age of 53.5 years, were wearing hearing aids, while another 30 people, with an average age of 53.3 years, were not utilizing any form of amplification. An audiologist assessed each and every patient. Routine audiometry, speech audiometry threshold tests were performed. People having sensorineural and mixed hearing loss with severe to profound deafness (71-90db); amplification using digital hearing aid with at least 6 months of hearing aid usage were included. Participants were not allowed if they had any comorbid illnesses, such as difficulties with auditory processing, neurodegenerative disorders, psychological problems including stress, or any other major medical concerns.
Test material:
Mini-Mental State Examination (MMSE) adapted from Folstein et al (1975) was used in this study [5]. It is an assessment tool for evaluating the cognitive state of the participants. MMSE a 30-point cognitive assessment tool that looks at different cognitive domains such as orientation (time and place)10, Registration 3, Attention/concentration 5, memory recall 3 but deliberately weighted towards tasks involving language such as language naming 2, language comprehension 1, three stage command 3, language writing 1, language repetition (reading) 1 and visuospatial abilities (drawing) 1. Both the hearing aid user and non-user groups each received 11 questions in total. Maximum score for each of the questions was varied from 1 to 5. The score of 25-30 suggested “Questionably significant”, 20-25 as “mild cognitive impairment”, 10-20 as “moderate cognitive impairment” and 0-10 as “severe cognitive impairment. Digit Span Test (DST) is a sub-test of the working memory test used in the Multi-Ethnic Study of Atherosclerosis (MESA). This test is conducted in two segment and requires the participant to repeat gradually increasing spans of numbers (e.g., 2-7-4) first forwards (8 items, in each item there are two sub test e.g.: 1a. and 1b.) and then backwards (7 items in each item there are two sub test e.g.: 1a. and 1b.). Two trials are conducted for each specified span length, and a point is given for each properly remembered span. Each span is scored ‘1’ (Pass) or ‘0’ (Fail). Scores range from 0 to 30. In forward digit span Test maximum score was 16 and in backward digit span Test maximum score was 14. Forward Digit Span test: In this span task, in which order of items of increasing length have to be reproduced in the order they were presented, they majorly assess the functioning of the working memory. Backward Digit Span test: In this span task, in which order of items have to reproduce in the opposite order, these task majorly assess the central executive memory. Combined Digit Span test: In this tests combined the total score of backward and forward digit span task.
Procedure:
The Hearing aid center at Gurugram and Best Hearing Solutions, two famous hearing aid clinics located in the Delhi NCR region of India, were randomly chosen for the people with severe to profound degree of hearing loss. All participants in this study had their case histories and ears examined at first. Individuals with variable hearing loss and any middle ear pathology were excluded. The frequencies used for conventional audiometry were (250, 500, 1000, 2000, 4000, and 8000 Hz), while the TDH 39 headphone was used for speech audiometry (SRT and SDS) with the Arphi Proton DX3 digital audiometer. Pure tone thresholds average calculated at 500, 1 kHz, 2 kHz and 4 kHz frequencies. Demographic data was gathered from each participant. In MMSE set of questions, question number 1,2,3,4,5 and 8 assessed the cognitive domains, 6,7,9 and 10 for language learning and question number 11 for visuospatial ability. All participants were capable of verbal and written responses of set of questions. Before administering the set of questions, all participants provided their verbal and written consent. The set of questions was supervised by the certified audiologist.
People with significant to severe hearing loss (53.3±5.43) who were wearing (HAU) hearing aids (25.7±2.97) and those who were not (NHAU) (22.1±5.11) were compared on their mean MMSE scores. The average MMSE score was determined by adding the answers to questions 1 through 11. The two-tailed hypothesis was assumed at the level of significance of (P<0.05). The t-test was employed to evaluate whether there was a statistically significant difference between these two groups. The outcome showed that HAU's mean MMSE score was substantially higher than NHAU's mean score. Refer Figure 1
Figure 1
The working memory under cognitive domain was investigated across hearing aid user and non user who had severe to profound deafness. An attempt was made to understand whether uses of hearing aid in severe to profound individuals can reestablished the cognitive abilities specially the working memory abilities. Forward, backward and combined digit span task was to use to measure working memory abilities. One of the earliest and the evaluation of forward and backward digit span is one of the neuropsychological tests of short-term verbal memory that is most frequently employed. In each case, the digit span is measured for forward and backward (reverse order) recall of the digit sequences. Digit sequences are presented beginning with a length of 2 digits, and two trails are presented at each increasing list length. Only discontinue test when the participant failed both
trails of the same span length (e.g., 3a and 3b) or when the maximal list length is reached (9 digit forward, 8 digit backward span test) Mean DST score of those wearing hearing aids and having severe to profound hearing loss (6.40±1.47) and people not wearing amplification device (5.33±1.12) were contrasted across each other. The mean DST score was computed by adding the forward and backward digit span task. The two-tailed hypothesis was assumed at the level of significance of (P<0 t(1,59)=3.6, P=.001)].>
Figure 2
After noticing a large difference between the mean DST scores for the HAU and NHAU groups, it was also compared between genders. Or, whether there was a difference in the mean DST score between genders. In other words, whether the mean DST score differed across the males (8.41±2.17) and females (7.62±1.85) in both HAU and NHAU groups. Independent t-test was performed at (P˂0.05) level of significance to check whether the mean DST score of gender differed significantly in the groups. The result revealed that no any statistical significant difference in mean DST score across gender was observed. In both HAU [t (1, 58) =0.22, P=0.23)] group and NHAU [t (1, 58) =.44, P=.26)] group, no any statistical significant difference in mean DST score across gender was observed. Refer figure 3.
Figure 3
In this study AWM was investigated people with severe to profound hearing loss who were equally divided into two group’s one wearing hearing aid (HAU) and the other not wearing hearing aid (NHAU). According to the examination of the data, the two groups (HAU and NHAU) had significantly different mean MMSE scores and mean DST scores. However, individuals wearing hearing aids had much greater cognitive abilities than non-users, including reading comprehension, visual and auditory working memory, and long-term declarative memory. But when compare the mean DST score across gender in both the groups, no any statistical differences were observed. Performance on any span task was unaffected by gender in a substantial way. As evident in this study, the rationale behind significant impact of hearing aid uses on cognitive performance and auditory working memory in the person with hearing loss depend on several factor. Review of literature support the findings in our study for reduce social isolation and improve depressive symptoms could explain the early effects of treatment for hearing loss in senior persons, particularly for short-term memory, cognitive function, and depression [6, 7]; Using electrical stimulation, the function and three-dimensional structure of the peripheral and central synapses may be preserved [8, 9]; auditory rehabilitation can counteract negative neuroplasticity processes [10]; Working memory and learning capacities may benefit from auditory/speech training, and gains in self-motivation, self-esteem, or self-confidence after rehabilitation treatments may also have a good impact on cognitive abilities. The central auditory system's capacity to combine binaural information and binaural loudness summation was improved by binaural hearing amplification. [11, 12]. Participants who received hearing aid rehabilitation within six months were included in the study. Less than six months of HA use might not be enough to restore working memory and cognitive functions, which are significantly damaged by the effects of severe to profound hearing loss. When hearing loss affects older people for a longer period of time, it frequently causes them to stop participating in many social activities, because of communicative challenges in social settings [13]. Such isolation-related behaviors may have an impact on both quality of life and socio-personal aspects of life. Reduced auditory and intellectual stimulation may result in central nervous system changes and may have an impact on the progression of dementia and cognitive decline. [4]. As a result, a prolonged unaided hearing threshold may gradually lower overall quality of life. [14]. The findings of this study support the necessity for more research into cognition and working memory in people with greater degree of hearing loss who are wearing amplification device. Hearing loss that ranges from severe to profound can have varying effects on one's mental health and listening challenges. An important public health issue, Presbycusis can develop in reduced lifestyle quality, loneliness, reliance, and dissatisfaction. [15]. Similar to this, socio-emotional stress brought on by hearing loss might result in varied degrees of difficulties as people get older. [16]. Additional complicating factors in the presentation of symptoms related to working memory and cognitive function include familial support, personal stress coping mechanisms, socio-personal-professional participation, listening abilities, and prior experience. Elderly patients with cognitive impairment should not be denied the current possibilities for auditory rehabilitation since the hearing system should be viewed as a crucial window for research into neurodegenerative illnesses. [17, 18]. Therefore, a thorough for those with severe to profound hearing loss, a rehabilitation program is advised, which should include audiological intervention in addition to mental health enhancement. [19, 20]. This finding generally corroborates the effortfulness hypothesis, which postulates that the additional effort required for a hearing-impaired listener to comprehend speech depletes cognitive processing resources that might otherwise be used to encode speech content in memory [12]. In other words, bottom-up and top-down cognitive processes that control the processing of auditory information influence speech understanding in daily life [21, 22]. A hearing-impaired person can mentally make up for lost information by "filling in" the gaps because speech contains repetitive information. Consequently, top-down cognitive compensatory mechanisms can successfully conceal a peripheral hearing loss and aid the hearing-impaired listener in functioning more efficiently in ordinary listening contexts [16, 22]. The impact on cognition and memory in people who have been using hearing aids for longer than six months will be the subject of future research. The long-term effects of hearing aid use on mental health and working memory have not been thoroughly studied, as is the case in the literature. Additional research shall clear the impact of cognition and memory in those people who worn hearing aids for more than six months. The long-term effects of hearing aid use on mental health and working memory have not been thoroughly studied, as is the case in the literature.
This study's primary goal was to determine whether the mean MMSE and DST score were different for person with HAU when compared with NHAU. As a result, mean MMSE and DST score was elevated in the HAU category but when compared across the gender no any statistical differences observed. It was clear that the duration and use of the hearing aid influences the pattern of cognitive and working memory recovery. These results can support the development of client-specific counseling for enhancement of cognitive and working memory tasks. Findings proposed when a user habituated to listening with hearing aid helps to ease cognitive processing to understand speech.
Sincere thanks to all the participants of this study.
Notes
Conflicts of Interest
The authors have no financial conflicts of interest.
Author Contributions
Conceptualization: all authors. Data curation; all authors. Formal analysis: Arun Kumar Yadav, Vijay Kumar. Funding acquisition: Arun Kumar Yadav, Amra Ahsan. Investigation; all Authors. Methodology: all authors. Project Administration: all authors.
Resources: all authors. Software: Arun Kumar Yadav, Vijay Kumar. Supervision: Amra Ahsan, Vijay Kumar, Arun Banik.
Validation: all authors. Visualization: all authors. Writing-original draft: Arun Kumar Yadav, Vijay Kumar. Writing-review and Editing: Amra Ahsan, Vijay Kumar, Arun Banik. Approval of final manuscript: all authors.
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To Dear Erin Aust, I would like to express my heartfelt appreciation for the opportunity to have my work published in this esteemed journal. The entire publication process was smooth and well-organized, and I am extremely satisfied with the final result. The Editorial Team demonstrated the utmost professionalism, providing prompt and insightful feedback throughout the review process. Their clear communication and constructive suggestions were invaluable in enhancing my manuscript, and their meticulous attention to detail and dedication to quality are truly commendable. Additionally, the support from the Editorial Office was exceptional. From the initial submission to the final publication, I was guided through every step of the process with great care and professionalism. The team's responsiveness and assistance made the entire experience both easy and stress-free. I am also deeply impressed by the quality and reputation of the journal. It is an honor to have my research featured in such a respected publication, and I am confident that it will make a meaningful contribution to the field.
"I am grateful for the opportunity of contributing to [International Journal of Clinical Case Reports and Reviews] and for the rigorous review process that enhances the quality of research published in your esteemed journal. I sincerely appreciate the time and effort of your team who have dedicatedly helped me in improvising changes and modifying my manuscript. The insightful comments and constructive feedback provided have been invaluable in refining and strengthening my work".
I thank the ‘Journal of Clinical Research and Reports’ for accepting this article for publication. This is a rigorously peer reviewed journal which is on all major global scientific data bases. I note the review process was prompt, thorough and professionally critical. It gave us an insight into a number of important scientific/statistical issues. The review prompted us to review the relevant literature again and look at the limitations of the study. The peer reviewers were open, clear in the instructions and the editorial team was very prompt in their communication. This journal certainly publishes quality research articles. I would recommend the journal for any future publications.
Dear Jessica Magne, with gratitude for the joint work. Fast process of receiving and processing the submitted scientific materials in “Clinical Cardiology and Cardiovascular Interventions”. High level of competence of the editors with clear and correct recommendations and ideas for enriching the article.
We found the peer review process quick and positive in its input. The support from the editorial officer has been very agile, always with the intention of improving the article and taking into account our subsequent corrections.
My article, titled 'No Way Out of the Smartphone Epidemic Without Considering the Insights of Brain Research,' has been republished in the International Journal of Clinical Case Reports and Reviews. The review process was seamless and professional, with the editors being both friendly and supportive. I am deeply grateful for their efforts.
To Dear Erin Aust – Editorial Coordinator of Journal of General Medicine and Clinical Practice! I declare that I am absolutely satisfied with your work carried out with great competence in following the manuscript during the various stages from its receipt, during the revision process to the final acceptance for publication. Thank Prof. Elvira Farina
Dear Jessica, and the super professional team of the ‘Clinical Cardiology and Cardiovascular Interventions’ I am sincerely grateful to the coordinated work of the journal team for the no problem with the submission of my manuscript: “Cardiometabolic Disorders in A Pregnant Woman with Severe Preeclampsia on the Background of Morbid Obesity (Case Report).” The review process by 5 experts was fast, and the comments were professional, which made it more specific and academic, and the process of publication and presentation of the article was excellent. I recommend that my colleagues publish articles in this journal, and I am interested in further scientific cooperation. Sincerely and best wishes, Dr. Oleg Golyanovskiy.
Dear Ashley Rosa, Editorial Coordinator of the journal - Psychology and Mental Health Care. " The process of obtaining publication of my article in the Psychology and Mental Health Journal was positive in all areas. The peer review process resulted in a number of valuable comments, the editorial process was collaborative and timely, and the quality of this journal has been quickly noticed, resulting in alternative journals contacting me to publish with them." Warm regards, Susan Anne Smith, PhD. Australian Breastfeeding Association.
Dear Jessica Magne, Editorial Coordinator, Clinical Cardiology and Cardiovascular Interventions, Auctores Publishing LLC. I appreciate the journal (JCCI) editorial office support, the entire team leads were always ready to help, not only on technical front but also on thorough process. Also, I should thank dear reviewers’ attention to detail and creative approach to teach me and bring new insights by their comments. Surely, more discussions and introduction of other hemodynamic devices would provide better prevention and management of shock states. Your efforts and dedication in presenting educational materials in this journal are commendable. Best wishes from, Farahnaz Fallahian.
Dear Maria Emerson, Editorial Coordinator, International Journal of Clinical Case Reports and Reviews, Auctores Publishing LLC. I am delighted to have published our manuscript, "Acute Colonic Pseudo-Obstruction (ACPO): A rare but serious complication following caesarean section." I want to thank the editorial team, especially Maria Emerson, for their prompt review of the manuscript, quick responses to queries, and overall support. Yours sincerely Dr. Victor Olagundoye.
Dear Ashley Rosa, Editorial Coordinator, International Journal of Clinical Case Reports and Reviews. Many thanks for publishing this manuscript after I lost confidence the editors were most helpful, more than other journals Best wishes from, Susan Anne Smith, PhD. Australian Breastfeeding Association.
Dear Agrippa Hilda, Editorial Coordinator, Journal of Neuroscience and Neurological Surgery. The entire process including article submission, review, revision, and publication was extremely easy. The journal editor was prompt and helpful, and the reviewers contributed to the quality of the paper. Thank you so much! Eric Nussbaum, MD
Dr Hala Al Shaikh This is to acknowledge that the peer review process for the article ’ A Novel Gnrh1 Gene Mutation in Four Omani Male Siblings, Presentation and Management ’ sent to the International Journal of Clinical Case Reports and Reviews was quick and smooth. The editorial office was prompt with easy communication.
Dear Erin Aust, Editorial Coordinator, Journal of General Medicine and Clinical Practice. We are pleased to share our experience with the “Journal of General Medicine and Clinical Practice”, following the successful publication of our article. The peer review process was thorough and constructive, helping to improve the clarity and quality of the manuscript. We are especially thankful to Ms. Erin Aust, the Editorial Coordinator, for her prompt communication and continuous support throughout the process. Her professionalism ensured a smooth and efficient publication experience. The journal upholds high editorial standards, and we highly recommend it to fellow researchers seeking a credible platform for their work. Best wishes By, Dr. Rakhi Mishra.
Dear Jessica Magne, Editorial Coordinator, Clinical Cardiology and Cardiovascular Interventions, Auctores Publishing LLC. The peer review process of the journal of Clinical Cardiology and Cardiovascular Interventions was excellent and fast, as was the support of the editorial office and the quality of the journal. Kind regards Walter F. Riesen Prof. Dr. Dr. h.c. Walter F. Riesen.
Dear Ashley Rosa, Editorial Coordinator, International Journal of Clinical Case Reports and Reviews, Auctores Publishing LLC. Thank you for publishing our article, Exploring Clozapine's Efficacy in Managing Aggression: A Multiple Single-Case Study in Forensic Psychiatry in the international journal of clinical case reports and reviews. We found the peer review process very professional and efficient. The comments were constructive, and the whole process was efficient. On behalf of the co-authors, I would like to thank you for publishing this article. With regards, Dr. Jelle R. Lettinga.
Dear Clarissa Eric, Editorial Coordinator, Journal of Clinical Case Reports and Studies, I would like to express my deep admiration for the exceptional professionalism demonstrated by your journal. I am thoroughly impressed by the speed of the editorial process, the substantive and insightful reviews, and the meticulous preparation of the manuscript for publication. Additionally, I greatly appreciate the courteous and immediate responses from your editorial office to all my inquiries. Best Regards, Dariusz Ziora
Dear Chrystine Mejia, Editorial Coordinator, Journal of Neurodegeneration and Neurorehabilitation, Auctores Publishing LLC, We would like to thank the editorial team for the smooth and high-quality communication leading up to the publication of our article in the Journal of Neurodegeneration and Neurorehabilitation. The reviewers have extensive knowledge in the field, and their relevant questions helped to add value to our publication. Kind regards, Dr. Ravi Shrivastava.
Dear Clarissa Eric, Editorial Coordinator, Journal of Clinical Case Reports and Studies, Auctores Publishing LLC, USA Office: +1-(302)-520-2644. I would like to express my sincere appreciation for the efficient and professional handling of my case report by the ‘Journal of Clinical Case Reports and Studies’. The peer review process was not only fast but also highly constructive—the reviewers’ comments were clear, relevant, and greatly helped me improve the quality and clarity of my manuscript. I also received excellent support from the editorial office throughout the process. Communication was smooth and timely, and I felt well guided at every stage, from submission to publication. The overall quality and rigor of the journal are truly commendable. I am pleased to have published my work with Journal of Clinical Case Reports and Studies, and I look forward to future opportunities for collaboration. Sincerely, Aline Tollet, UCLouvain.
Dear Ms. Mayra Duenas, Editorial Coordinator, International Journal of Clinical Case Reports and Reviews. “The International Journal of Clinical Case Reports and Reviews represented the “ideal house” to share with the research community a first experience with the use of the Simeox device for speech rehabilitation. High scientific reputation and attractive website communication were first determinants for the selection of this Journal, and the following submission process exceeded expectations: fast but highly professional peer review, great support by the editorial office, elegant graphic layout. Exactly what a dynamic research team - also composed by allied professionals - needs!" From, Chiara Beccaluva, PT - Italy.
Dear Maria Emerson, Editorial Coordinator, we have deeply appreciated the professionalism demonstrated by the International Journal of Clinical Case Reports and Reviews. The reviewers have extensive knowledge of our field and have been very efficient and fast in supporting the process. I am really looking forward to further collaboration. Thanks. Best regards, Dr. Claudio Ligresti
Dear Chrystine Mejia, Editorial Coordinator, Journal of Neurodegeneration and Neurorehabilitation. “The peer review process was efficient and constructive, and the editorial office provided excellent communication and support throughout. The journal ensures scientific rigor and high editorial standards, while also offering a smooth and timely publication process. We sincerely appreciate the work of the editorial team in facilitating the dissemination of innovative approaches such as the Bonori Method.” Best regards, Dr. Matteo Bonori.
I recommend without hesitation submitting relevant papers on medical decision making to the International Journal of Clinical Case Reports and Reviews. I am very grateful to the editorial staff. Maria Emerson was a pleasure to communicate with. The time from submission to publication was an extremely short 3 weeks. The editorial staff submitted the paper to three reviewers. Two of the reviewers commented positively on the value of publishing the paper. The editorial staff quickly recognized the third reviewer’s comments as an unjust attempt to reject the paper. I revised the paper as recommended by the first two reviewers.
Dear Maria Emerson, Editorial Coordinator, Journal of Clinical Research and Reports. Thank you for publishing our case report: "Clinical Case of Effective Fetal Stem Cells Treatment in a Patient with Autism Spectrum Disorder" within the "Journal of Clinical Research and Reports" being submitted by the team of EmCell doctors from Kyiv, Ukraine. We much appreciate a professional and transparent peer-review process from Auctores. All research Doctors are so grateful to your Editorial Office and Auctores Publishing support! I amiably wish our article publication maintained a top quality of your International Scientific Journal. My best wishes for a prosperity of the Journal of Clinical Research and Reports. Hope our scientific relationship and cooperation will remain long lasting. Thank you very much indeed. Kind regards, Dr. Andriy Sinelnyk Cell Therapy Center EmCell
Dear Editorial Team, Clinical Cardiology and Cardiovascular Interventions. It was truly a rewarding experience to work with the journal “Clinical Cardiology and Cardiovascular Interventions”. The peer review process was insightful and encouraging, helping us refine our work to a higher standard. The editorial office offered exceptional support with prompt and thoughtful communication. I highly value the journal’s role in promoting scientific advancement and am honored to be part of it. Best regards, Meng-Jou Lee, MD, Department of Anesthesiology, National Taiwan University Hospital.
Dear Editorial Team, Journal-Clinical Cardiology and Cardiovascular Interventions, “Publishing my article with Clinical Cardiology and Cardiovascular Interventions has been a highly positive experience. The peer-review process was rigorous yet supportive, offering valuable feedback that strengthened my work. The editorial team demonstrated exceptional professionalism, prompt communication, and a genuine commitment to maintaining the highest scientific standards. I am very pleased with the publication quality and proud to be associated with such a reputable journal.” Warm regards, Dr. Mahmoud Kamal Moustafa Ahmed
Dear Maria Emerson, Editorial Coordinator of ‘International Journal of Clinical Case Reports and Reviews’, I appreciate the opportunity to publish my article with your journal. The editorial office provided clear communication during the submission and review process, and I found the overall experience professional and constructive. Best regards, Elena Salvatore.
Dear Mayra Duenas, Editorial Coordinator of ‘International Journal of Clinical Case Reports and Reviews Herewith I confirm an optimal peer review process and a great support of the editorial office of the present journal
Dear Editorial Team, Clinical Cardiology and Cardiovascular Interventions. I am really grateful for the peers review; their feedback gave me the opportunity to reflect on the message and impact of my work and to ameliorate the article. The editors did a great job in addition by encouraging me to continue with the process of publishing.
Dear Cecilia Lilly, Editorial Coordinator, Endocrinology and Disorders, Thank you so much for your quick response regarding reviewing and all process till publishing our manuscript entitled: Prevalence of Pre-Diabetes and its Associated Risk Factors Among Nile College Students, Sudan. Best regards, Dr Mamoun Magzoub.
International Journal of Clinical Case Reports and Reviews is a high quality journal that has a clear and concise submission process. The peer review process was comprehensive and constructive. Support from the editorial office was excellent, since the administrative staff were responsive. The journal provides a fast and timely publication timeline.
Dear Maria Emerson, Editorial Coordinator of International Journal of Clinical Case Reports and Reviews, What distinguishes International Journal of Clinical Case Report and Review is not only the scientific rigor of its publications, but the intellectual climate in which research is evaluated. The submission process is refreshingly free of unnecessary formal barriers and bureaucratic rituals that often complicate academic publishing without adding real value. The peer-review system is demanding yet constructive, guided by genuine scientific dialogue rather than hierarchical or authoritarian attitudes. Reviewers act as collaborators in improving the manuscript, not as gatekeepers imposing arbitrary standards. This journal offers a rare balance: high methodological standards combined with a respectful, transparent, and supportive editorial approach. In an era where publishing can feel more burdensome than research itself, this platform restores the original purpose of peer review — to refine ideas, not to obstruct them Prof. Perlat Kapisyzi, FCCP PULMONOLOGIST AND THORACIC IMAGING.
Dear Grace Pierce, International Journal of Clinical Case Reports and Reviews I appreciate the opportunity to review for Auctore Journal, as the overall editorial process was smooth, transparent and professionally managed. This journal maintains high scientific standards and ensures timely communications with authors, which is truly commendable. I would like to express my special thanks to editor Grace Pierce for his constant guidance, promt responses, and supportive coordination throughout the review process. I am also greatful to Eleanor Bailey from the finance department for her clear communication and efficient handling of all administrative matters. Overall, my experience with Auctore Journal has been highly positive and rewarding. Best regards, Sabita sinha
Dear Mayra Duenas, Editorial Coordinator of the journal IJCCR, I write here a little on my experience as an author submitting to the International Journal of Clinical Case Reports and Reviews (IJCCR). This was my first submission to IJCCR and my manuscript was inherently an outsider’s effort. It attempted to broadly identify and then make some sense of life’s under-appreciated mysteries. I initially had responded to a request for possible submissions. I then contacted IJCCR with a tentative topic for a manuscript. They quickly got back with an approval for the submission, but with a particular requirement that it be medically relevant. I then put together a manuscript and submitted it. After the usual back-and-forth over forms and formality, the manuscript was sent off for reviews. Within 2 weeks I got back 4 reviews which were both helpful and also surprising. Surprising in that the topic was somewhat foreign to medical literature. My subsequent updates in response to the reviewer comments went smoothly and in short order I had a series of proofs to evaluate. All in all, the whole publication process seemed outstanding. It was both helpful in terms of the paper’s content and also in terms of its efficient and friendly communications. Thank you all very much. Sincerely, Ted Christopher, Rochester, NY.
