Awareness and Prevalence of Polycystic Ovarian Syndrome (PCOS) among Nigerian Women: A Case Study of Abia State

Research Article | DOI: https://doi.org/10.31579/JRHI-2025/001

Awareness and Prevalence of Polycystic Ovarian Syndrome (PCOS) among Nigerian Women: A Case Study of Abia State

  • Emmanuel M. Akwuruoha 1*
  • Augustine I. Airaodion 2

1Department of Obstetrics and Gynecology, Abia State University Teaching Hospital, Aba, Nigeria.

2Department of Biochemistry, Lead City University, Ibadan, Oyo State, Nigeria.

*Corresponding Author: Emmanuel M. Akwuruoha, Department of Obstetrics and Gynecology, Abia State University Teaching Hospital, Aba, Nigeria.

Citation: Emmanuel M. Akwuruoha, Augustine I. Airaodion, (2026), Awareness and Prevalence of Polycystic Ovarian Syndrome (PCOS) among Nigerian Women: A Case Study of Abia State, Reproductive Health and Issues, 1(1); DOI:10.31579/JRHI-2025/001

Copyright: © 2025, Emmanuel M. Akwuruoha. This is an open-access article distributed under the terms of The Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Received: 24 November 2025 | Accepted: 08 December 2025 | Published: 24 December 2025

Keywords: polycystic ovarian syndrome; awareness; prevalence; women’s health

Abstract

Background: Polycystic ovarian syndrome (PCOS) is a prevalent endocrine disorder among women of reproductive age, often underdiagnosed due to low awareness. Understanding its prevalence and level of awareness is crucial for improving women’s reproductive health in Nigeria.

Materials and Methods: A hospital-based descriptive cross-sectional study was conducted at the Abia State University Teaching Hospital (ABSUTH), Aba, involving 250 women aged 15–49 years. Participants were selected using systematic random sampling. Data were collected through a structured interviewer-administered questionnaire, clinical assessments, and laboratory investigations. Hormonal assays and pelvic ultrasonography were employed to confirm PCOS diagnosis based on the Rotterdam criteria. Data analysis was performed using SPSS version 26, with descriptive and inferential statistics applied; statistical significance was set at p < 0.05.

Results: The mean age of participants was 31.92 ± 7.86 years, with 60.4% having tertiary education and 62.8% residing in urban areas. Awareness of PCOS was generally moderate (48.4%), while 22.8% demonstrated good awareness and 28.8% poor awareness. The media (48.4%) was the most common source of information, followed by healthcare professionals (22.8%). The mean BMI was 27.13 ± 5.41 kg/m², with 32.0% overweight and 16.4% obese. Clinical and hormonal assessments showed significant correlations between BMI, hirsutism (mFG score), and LH/FSH ratio (p < 0.05). The prevalence of PCOS was 9.6% (24/250). Chi-square analysis revealed significant associations between PCOS and BMI category (χ² = 10.66, p = 0.014) as well as place of residence (χ² = 3.87, p = 0.049), but not with age, education, or marital status.

Conclusion: The study revealed a moderate level of awareness and a PCOS prevalence of 9.6% among women in Abia State. Obesity and urban residence were significantly associated with PCOS, highlighting the need for enhanced public health education and targeted interventions to improve awareness, early detection, and management of PCOS in Nigerian women.

Introduction

Polycystic ovary syndrome (PCOS) is a heterogeneous endocrine disorder and one of the most common conditions affecting women of reproductive age worldwide. It is characterized by variable combinations of oligo- or anovulation, clinical and/or biochemical hyperandrogenism, and polycystic ovarian morphology on ultrasound. The syndrome is pathophysiologically complex and strongly associated with insulin resistance, dyslipidaemia, obesity and adverse cardiometabolic outcomes; its clinical expression and long-term health consequences extend beyond reproductive dysfunction to include increased risks of type 2 diabetes, metabolic syndrome, cardiovascular disease and impacts on mental health such as anxiety and depression. These clinical and metabolic burdens make PCOS an important public-health concern that intersects reproductive, metabolic and psychological health domains [1]. 

Accurate diagnosis and epidemiological characterization of PCOS are challenged by heterogeneity in presentation and differences in diagnostic criteria. The Rotterdam consensus remains widely used and defines PCOS by the presence of two of three features: oligo-anovulation, hyperandrogenism (clinical or biochemical), and polycystic ovarian morphology (PCOM) on ultrasound. Debate continues around the sensitivity and specificity of each criterion, the utility of ultrasound (especially in adolescents), and standardization of androgen assays. Such methodological variability contributes to the wide range of reported prevalence estimates across populations and complicates comparisons between studies [2]. 

Globally, the prevalence of PCOS varies markedly by diagnostic criteria and population studied, with estimates commonly ranging from low single digits to over 15% in some settings; this variability reflects true epidemiological diversity as well as differences in case definitions, sampling frames and study methodologies. In Nigeria, recent multicentre and population-based work indicates that PCOS is not uncommon: a national epidemiology project reported an overall prevalence in an unselected reproductive-age Nigerian population of approximately 8.6%, with multiple phenotypes observed and phenotypes reflecting varying combinations of ovulatory dysfunction, hyperandrogenism and ovarian morphology. These findings suggest that PCOS represents a substantive reproductive-endocrine health issue for Nigerian women and highlight the need for locally relevant data to better target screening, diagnosis and management strategies [3]. 

Despite emerging national-level data, there remains a paucity of robust sub-national studies that quantify both the prevalence and public awareness of PCOS across Nigeria’s diverse states and communities. Subnational epidemiological data are essential because prevalence, phenotype distribution and associated comorbidities may vary with ethnicity, urbanization, socioeconomic status, nutritional patterns and access to healthcare—factors that differ considerably across Nigerian states. Where localized studies do exist, they often focus on clinic-based samples (for example, women seeking infertility care), or specific subpopulations such as university students, which may overestimate or underestimate population prevalence when extrapolated to the general community. The limited availability of state-level prevalence estimates and contemporaneous data on PCOS awareness impedes the design of contextually appropriate public-health interventions, educational programs and clinical pathways in many regions [4]. 

Awareness and knowledge about PCOS among women and healthcare consumers are critical determinants of timely care-seeking, early diagnosis and adoption of lifestyle or medical therapies that can mitigate both reproductive and metabolic complications. Internationally and in low- and middle-income settings, studies of awareness among adolescents, university students, and reproductive-age women reveal variable knowledge levels and common misconceptions about symptoms, causes and long-term risks; such knowledge gaps may delay diagnosis and contribute to psychological distress. In Nigeria, several surveys and small studies have documented inconsistent awareness and variable sources of information (peers, social media, and health professionals), underscoring the need to assess awareness comprehensively at a community and state level to inform targeted health education and service planning [5]. 

Abia State, like many sub-national units in Nigeria, has specific sociodemographic and health-system characteristics—including a mix of urban and rural populations, variable access to specialist reproductive health services, and diverse health literacy—that may influence both the true prevalence of PCOS and the level of public awareness. To date, there are limited published epidemiologic studies explicitly focused on Abia State that combine community-based prevalence estimation with systematic measures of awareness and health-seeking behaviour. This gap constrains policymakers, clinicians and public-health practitioners from tailoring preventive, diagnostic and management strategies that account for local needs. A focused study in Abia State will therefore provide critical, actionable evidence on disease burden and community awareness, inform state-level reproductive and metabolic health planning, and serve as a model for similar sub-national assessments in Nigeria [6]. 

Given the burden of reproductive dysfunction and cardiometabolic comorbidity associated with PCOS, as well as the documented variability in awareness and diagnostic practice, research that measures both prevalence and awareness at the state level is justified. A combined epidemiological and awareness assessment in Abia State will bridge current knowledge gaps by estimating community prevalence using standardized diagnostic approaches, characterizing phenotype distribution and metabolic correlates, and quantifying awareness, attitudes and care-seeking patterns among women. The results will support the development of locally appropriate education, screening and management algorithms and help integrate PCOS considerations into broader women’s health and non-communicable disease strategies in Abia State and comparable settings across Nigeria.

Materials And Methods

Study Area

This study was carried out at the Abia State University Teaching Hospital (ABSUTH), Aba, Nigeria. ABSUTH is a tertiary healthcare institution located in Aba South Local Government Area of Abia State, in the South-East geopolitical zone of Nigeria. The hospital serves as a referral centre for primary and secondary health facilities across Abia State and neighboring states. The Obstetrics and Gynaecology Department of ABSUTH, which provides services to women of reproductive age, was chosen as the study site due to its large patient turnover and specialized care in women’s health.

Study Design

The study adopted a hospital-based descriptive cross-sectional design to assess both the awareness and prevalence of polycystic ovarian syndrome (PCOS) among women attending the gynaecology and general outpatient clinics of ABSUTH.

Study Population

The study population consisted of women of reproductive age (15–49 years) who attended ABSUTH during the study period. Both outpatients and women presenting for gynaecological consultations were included, irrespective of their presenting complaints.

Inclusion Criteria

  1. Women aged 15–49 years attending ABSUTH during the study period.
  2. Women who provided informed consent to participate.
  3. Women who were residents of Abia State for at least 12 months before the study.
  4.  

Exclusion Criteria

  1. Pregnant women at the time of data collection.
  2. Women with known endocrine disorders other than PCOS (e.g., thyroid dysfunction, Cushing’s syndrome).
  3. Women on long-term hormonal therapy or steroids.
  4. Critically ill patients are unable to participate in the interview or diagnostic processes.
  5.  

Sample Size Determination

The sample size was determined using Cochran's formula for estimating population proportions, as outlined by Akwuruoha et al [7].

n =     

The formula components are defined as follows:

  • n represents the minimum required sample size.
  • Z is set at 1.96, corresponding to a 95% confidence level.
  • P denotes the established prevalence of PCOS in Southeast Nigeria.
  • e signifies the allowable margin of error, fixed at 5% (0.05).

q = 1 - p

A recent study conducted by Ugwu et al. [8] reported the prevalence of PCOS in Southeast Nigeria as 18.1% 

P = 18.1% = 0.181

q = 1 – 0.181

= 0.819

n =  

n =  

n = = 227.79

The minimum sample size was 228, but it was adjusted to 250 to account for a 10% non-response rate.

Sampling Technique

A systematic random sampling technique was used. Using the ANC attendance register, the sampling interval was determined by dividing the estimated number of eligible pregnant women attending ANC during the study period by the required sample size [9]. The first participant was selected randomly, and every 5th eligible woman was subsequently recruited until the sample size was attained.

Data Collection Instruments

1. Structured Questionnaire

A pretested, interviewer-administered structured questionnaire was used to collect data. The questionnaire had four sections:

  • Section A: Socio-demographic characteristics (age, marital status, education, occupation, residence, parity).
  • Section B: Awareness of PCOS (knowledge of symptoms, causes, complications, and treatment options).
  • Section C: Sources of information (media, healthcare professionals, peers, internet).

2. Clinical Assessment

A focused physical examination was conducted, which included:

  • Anthropometric measurements: Height, weight, and waist-hip ratio. Body Mass Index (BMI) was calculated.
  • Hirsutism scoring: Modified Ferriman–Gallwey (mFG) score was used to assess the degree of hirsutism.

3. Laboratory Investigations

To establish the prevalence of PCOS, participants with clinical features suggestive of PCOS underwent confirmatory tests:

  • Hormonal assays: Serum luteinizing hormone (LH), follicle-stimulating hormone (FSH), LH/FSH ratio, total testosterone, and prolactin.
  • Pelvic ultrasonography: Transabdominal or transvaginal ultrasound was performed to evaluate ovarian morphology. The Rotterdam Criteria [10] were used to confirm PCOS diagnosis, requiring at least two of the following:
  1. Oligo- or anovulation
  2. Clinical and/or biochemical signs of hyperandrogenism
  3. Polycystic ovarian morphology on ultrasound

Data Collection Procedure

Data collection was carried out over a 3-month period. Trained research assistants (nurses and resident doctors) administered the questionnaires and assisted with anthropometric measurements. Blood samples were collected under aseptic conditions by qualified laboratory scientists, and hormonal assays were analyzed at the ABSUTH laboratory using ELISA kits. Ultrasonographic evaluations were performed by a certified radiologist.

Validity and Reliability

Content validity of the questionnaire was ensured through expert review by gynecologists, endocrinologists, and public health specialists. A pilot study involving 20 women was conducted at Aba General Hospital to pretest the instrument. Necessary adjustments were made before final administration. Reliability testing using Cronbach’s alpha yielded a coefficient of 0.81, indicating high internal consistency.

Data Management and Analysis

Completed questionnaires were checked daily for completeness. Data were coded and entered into Statistical Package for the Social Sciences (SPSS) version 26.0. Descriptive statistics (frequencies, percentages, means, and standard deviations) were used to summarize awareness levels and socio-demographic data. Inferential statistics such as the Chi-square test and logistic regression analysis were employed to determine associations between awareness, prevalence, and socio-demographic variables. A p-value < 0>

Ethical Considerations

Written informed consent was obtained from all participants after explaining the purpose, procedures, potential risks, and benefits of the study. Confidentiality and anonymity were maintained throughout the study. Participants diagnosed with PCOS were counselled and referred to the gynaecology unit for appropriate management.

Results

The socio-demographic profile of participants shows that the majority were aged 25–34 years (36.8%), married (64.4%), attained tertiary education (60.4%), employed in the formal sector (48.4%), resided in urban areas (62.8%), and were predominantly multiparous (42.4%) (Table 1).

Awareness of polycystic ovary syndrome (PCOS) was generally fair, as most participants agreed that PCOS causes infertility (65.6%), irregular menstruation is a symptom (75.2%), excessive hair growth is associated with the condition (68.0%), obesity increases its risk (66.8%), and that it can be managed with lifestyle modification (70.4%) (Table 2). Overall awareness levels showed that nearly half of the respondents had moderate awareness (48.4%), followed by poor awareness (28.8%) and good awareness (22.8%) (Figure 1). Media sources were the most common source of information (48.4%), followed by healthcare professionals (22.8%), peers/family (19.6%), and internet/social media (9.2%) (Figure 2).

Anthropometric and clinical variables revealed a mean age of 31.92 ± 7.86 years, BMI of 27.13 ± 5.41 kg/m², waist–hip ratio of 0.86 ± 0.07, and mFG score of 6.84 ± 3.91 (Table 3). The BMI distribution showed that nearly half of the respondents had normal BMI (46.8%), while 32.0% were overweight and 16.4% obese (Table 4). Hormonal assay results showed mean LH 6.21 ± 2.14 IU/L, FSH 5.12 ± 1.87 IU/L, LH/FSH ratio 1.22 ± 0.54, testosterone 0.58 ± 0.21 ng/mL, and prolactin 12.45 ± 5.32 ng/mL (Table 5).

The prevalence of PCOS based on Rotterdam criteria was 9.6% among participants (Figure 3). Correlation analysis indicated weak but significant positive associations between BMI and mFG score (r = 0.28, p < 0 xss=removed xss=removed xss=removed xss=removed>

Chi-square analysis demonstrated that BMI category was significantly associated with PCOS (χ² = 10.66, p = 0.014), with obesity contributing to more cases. Residence also showed a borderline significant association with PCOS (χ² = 3.87, p = 0.049), with higher prevalence in urban participants. However, age group, education level, and marital status did not show significant associations with PCOS (Table 7).

VariableCategoryFrequency (n = 250)Percentage (%)
Age15–24 years4919.60
 25–34 years9236.80
 35–44 years7128.40
 45–49 years3815.20
 Total250100.00
Marital StatusSingle5722.80
 Married16164.40
 Divorced93.60
 Widowed31.20
 Cohabiting208.00
 Total250100.00
Educational LevelNo formal education52.00
 Primary education2610.40
 Secondary education6827.20
 Tertiary education15160.40
 Total250100.00
OccupationEmployed (formal)12148.40
 Unemployed4919.60
 Student2610.40
 Self-employed4518.00
 Homemaker93.60
 Total250100.00
ResidenceUrban15762.80
 Rural9337.20
 Total250100.00
ParityNulliparous7831.20
 Primiparous6626.40
 Multiparous10642.40
 Total250100.00

Table 1: Socio-demographic characteristics

Awareness ItemStrongly Disagree n (%)Disagree n (%)Neutral n (%)

Agree  

n (%)

Strongly Agree n (%)
PCOS causes infertility18 (7.2)27 (10.8)41 (16.4)96 (38.4)68 (27.2)
Irregular menstruation is a symptom of PCOS9 (3.6)15 (6.0)38 (15.2)104 (41.6)84 (33.6)
Excessive hair growth (hirsutism) is associated with PCOS12 (4.8)21 (8.4)47 (18.8)102 (40.8)68 (27.2)
Obesity increases risk of PCOS16 (6.4)25 (10.0)42 (16.8)101 (40.4)66 (26.4)
PCOS can be managed with lifestyle modification11 (4.4)19 (7.6)44 (17.6)109 (43.6)67 (26.8)

Table 2: Awareness of PCOS

Figure 1: Awareness Level of PCOS

Figure 2: Sources of information on PCOS

VariableMean ± SD
Age (years)31.92 ± 7.86
Body mass index (kg/m²)27.13 ± 5.41
Waist-hip ratio0.86 ± 0.07
Modified Ferriman–Gallwey score (mFG)6.84 ± 3.91

Table 3: Anthropometric and Clinical Continuous Variables

 

BMI categoryFrequencyPercentage (%)
Underweight (BMI < 18>124.80
Normal (BMI 18.5–24.9)11746.80
Overweight (BMI 25.0–29.9)8032.00
Obese (BMI ≥ 30)4116.40
Total250100.00

Table 4: Anthropometric categories (BMI)

Hormone / ratioMean ± SD
LH (IU/L)6.21 ± 2.14
FSH (IU/L)5.12 ± 1.87
LH/FSH ratio1.22 ± 0.54
Total testosterone (ng/mL)0.58 ± 0.21
Prolactin (ng/mL)12.45 ± 5.32

Table 5: Hormonal assay of Participants

Figure 3: Prevalence of PCOS (diagnosed using Rotterdam criteria)

Variable pairPearson rp-value
BMI vs mFG score0.28<0>
BMI vs LH/FSH ratio0.220.001
mFG score vs LH/FSH ratio0.31<0>
Age vs BMI0.120.060
Age vs mFG score0.020.780
Awareness score vs Education level0.47<0>
Awareness score vs Age-0.050.420

Table 6: Correlation analysis (Pearson’s r) of selected continuous variables

Categorical variableχ²dfp-value
Age group (15–24, 25–34, 35–44, 45–49) vs PCOS2.7730.429
BMI category vs PCOS10.6630.014*
Residence (Urban / Rural) vs PCOS3.8710.049*
Education level vs PCOS0.8030.850
Marital status vs PCOS1.0540.903

Table 7: Chi-square analysis (associations between PCOS status and categorical variables) Values are significantly different at p<0>

Discussion

In our study, the age distribution of participants showed that the largest proportion fell within the 25–34 years bracket (36.8%), followed by the 35–44 years bracket (28.4%) and the 15–24 years bracket (19.6%). This age pattern is broadly consistent with reproductive-age sampling in many PCOS epidemiological studies, as the highest-risk window often lies in the mid-to-late reproductive years. For example, the Nigeria-PEP (Nigeria PCOS Epidemiology & Phenotype) study similarly recruited women in comparable reproductive age bands [11].

Regarding marital status, most respondents (64.4 %) were married, with a smaller proportion single (22.8 %) or cohabiting (8.0 %). Educational attainment was high, with 60.4 % having a tertiary education, while only 2 % had no formal education. Employment patterns reflected a mixed economy: 48.4 % in formal employment, 18 % self-employed, while nearly 20 % unemployed and 10.4 % students. In terms of place of r sidence, 62.8 % lived in urban settings, 37.2 % rural; parity distribution showed 31.2 % nulliparous, 26.4 % primiparous, and 42.4 % multiparous.

These socio-demographic features are relevant both for interpreting awareness levels and for exploring risk correlates of PCOS. The relatively high level of tertiary education in our sample might predispose individuals toward better health literacy and awareness compared to the general population. However, selection bias (e.g. sampling from health facilities or better-connected communities) might partially account for this.

Our awareness assessment revealed that substantial proportions of women recognized key features of PCOS: for instance, 38.4 % agreed and 27.2 % strongly agreed that PCOS can cause infertility (i.e. total ~65.6 % agreement), 41.6 % agreed and 33.6 % strongly agreed that irregular menstruation is a symptom (~75.2 % agreement), 40.8 % agreed and 27.2 % strongly agreed that excessive hair growth associates with PCOS (~68.0 % agreement), and similar levels for obesity as risk and lifestyle management as option. Using these items, we classified overall awareness levels, finding 22.8 % had “good awareness,” 48.4 % “moderate awareness,” and 28.8 % “poor awareness.”

These results suggest that while a fair portion of women are aware of major symptoms or risk factors of PCOS, deep or comprehensive knowledge is modest. The strong associations (e.g. between awareness and education: Pearson r = 0.47, p < 0>

Comparatively, previous Nigerian and African studies have often reported lower levels of awareness or knowledge gaps. For instance, Olotu & Okon [12] surveyed female undergraduates and found that about 35 % of respondents “had no idea what PCOS was or how it develops.” In other settings, surveys of general female populations often reveal that many women confuse PCOS with other menstrual disorders or do not know its metabolic implications. Many studies have also pointed out that because PCOS is underdiagnosed and underemphasized in reproductive health education, knowledge remains patchy in low-resourced settings [13].

That we observed nearly half of respondents in a “moderate” awareness category suggests some improvement (perhaps due to mass media, increasing internet/social media penetration, or reproductive health campaigns), but the 28.8 % with poor awareness indicates that large gaps remain. The distribution of information sources corroborates this: nearly half (48.4 %) cited media (TV/radio/newspapers), only 22.8 % cited healthcare professionals, 19.6 % peers/family, and 9.2 % internet. The relatively modest role of healthcare professionals signals a lost opportunity for provider-based education. These patterns emphasize the need to strengthen reproductive health education (through formal health services, community outreach, and mass media) to ensure better recognition, early consultation, and timely diagnosis of PCOS.

In our sample, the mean age was 31.92 ± 7.86 years, mean BMI 27.13 ± 5.41 kg/m², and waist–hip ratio 0.86 ± 0.07. The mean modified Ferriman–Gallwey (mFG) score was 6.84 ± 3.91. In terms of BMI categories, 4.8 % were underweight, 46.8 % normal weight, 32.0 % overweight, and 16.4 % obese. Hormonal assays showed mean LH 6.21 ± 2.14 IU/L, FSH 5.12 ± 1.87 IU/L, LH/FSH ratio 1.22 ± 0.54, total testosterone 0.58 ± 0.21 ng/mL, and prolactin 12.45 ± 5.32 ng/mL.

These anthropometric and biochemical values are comparable to those of many PCOS and general reproductive age cohorts. The mean BMI of ~27 kg/m² places the average participant in the “overweight” category, reflecting a trend toward elevated body weight in reproductive-aged women in Nigeria and elsewhere. For comparison, the Nigeria-PEP study reported a mean BMI of 26.6 (±9.2) in their community cohort [11]. Many other PCOS cohorts elsewhere report average BMIs in the overweight-to-obese range [14].

That roughly one-third of our respondents were overweight and 16.4 % obese aligns with global observations that overweight/obesity is common in women of reproductive age and particularly among those with PCOS risk. Indeed, some authors have noted that more than half of women with PCOS are overweight or obese, and that weight loss is often a frontline management recommendation [12]. The waist–hip ratio average of 0.86 also suggests moderate central adiposity, known to correlate with metabolic risk.

The average mFG of ~6.8 indicates mild-to-moderate hirsutism in many respondents, though individual variability likely exists. In many studies of PCOS, the presence of hirsutism as measured by mFG is a key clinical marker. The hormonal parameters—particularly the LH/FSH ratio average of 1.22—are within what might be expected in many women, though not dramatically elevated. The literature often finds elevated LH or elevated LH:FSH ratio in PCOS populations, though this is variable across phenotypes and ethnic groups [14].  For instance, some Nigerian PCOS studies have observed significantly higher LH levels and LH:FSH ratios in PCOS subjects compared to controls [15]. Thus, while our hormonal findings are not extreme, they suggest the presence of mild to moderate endocrine perturbations in the sample, consistent with the somewhat low prevalence (next section) and with the heterogeneous nature of PCOS phenotypes.

Using the Rotterdam criteria, we diagnosed PCOS in 24 of 250 participants, yielding a prevalence of 9.60 %. The remaining 226 (90.40 %) did not meet the diagnostic threshold. Our observed prevalence is broadly in line with many community-based estimates. Globally, PCOS prevalence is often reported in the range 5–20 %, depending on the population, diagnostic criteria, and ascertainment method [14]. In Nigeria, published prevalence figures have varied. For example, the Nigeria-PEP study (community-based) reported a prevalence of ~8.6 % in unselected Nigerian reproductive-aged women [11].  Earlier hospital-based studies in Nigerian infertile populations have reported higher rates (e.g. 12.2 %, 16.7 %) using Rotterdam or related criteria [15].  The discrepancy is expected: infertile clinic populations tend to have enriched disease prevalence relative to general populations.

For instance, in Enugu, Nigeria, a study of infertile women reported PCOS prevalence estimates in the 12–18 % range [15].  Our lower community-level prevalence suggests that a majority of women do not manifest full-blown PCOS under the diagnostic criteria, but a nontrivial minority do—and many might remain undiagnosed or subclinical. It is also worth noting that phenotype distribution matters. In some populations (including African), the milder or "non-hyperandrogenic" PCOS phenotypes may predominate, which may reduce overt biochemical or clinical detection. The Nigeria-PEP study, for instance, found that non-hyperandrogenic (phenotype D) PCOS was relatively common [11]. Our result may partly reflect a mixture of phenotypes with milder endocrine disruption, which may be harder to detect without detailed assays or imaging. The prevalence we observed (9.6 %) is thus plausible, and falls in the lower-to-middle range of what has been documented in Nigeria and elsewhere. It underscores that while not extremely common, PCOS is present at appreciable levels in Abia State, warranting attention.

In this study, we also examined correlations among anthropometric, clinical and endocrine variables and tested categorical associations with PCOS status. Our Pearson correlation and chi-square results largely align with established pathophysiology and with findings from several prior studies, while also highlighting features that appear sample-specific.

We found a weak-to-moderate positive correlation between body mass index (BMI) and hirsutism severity (mFG score) (r = 0.28, p < 0>

BMI also showed a weak positive correlation with the LH:FSH ratio (r = 0.22, p = 0.001). Several studies have reported altered gonadotropin patterns in PCOS and have investigated how obesity modifies these patterns. Some reports describe increased LH: FSH with greater adiposity, while others find either no clear relationship or even an inverse association depending on the cohort and the degree of insulin resistance present [18]. Our finding of a modest positive relationship suggests that, in our cohort, higher BMI was accompanied by a slight elevation in gonadotrophin imbalance; this could reflect the combined effects of obesity-driven hyperinsulinaemia and ovarian dysfunction on hypothalamic–pituitary signalling, but inter-study differences in sample selection and timing of hormonal assays mean this relationship should be interpreted cautiously [18].

Hirsutism (mFG score) correlated more strongly with LH:FSH ratio (r = 0.31, p < 0>

Age demonstrated only weak or null relationships with BMI and mFG score in our sample (Age vs BMI: r = 0.12, p = 0.060; Age vs mFG: r = 0.02, p = 0.780). The non-significant trend toward higher BMI with advancing reproductive age is biologically plausible, given age-associated metabolic changes, but our data did not show a statistically reliable increase. Similarly, hirsutism severity did not vary meaningfully across the 15–49-year span in this cohort, a finding that aligns with some prior reports that document little or inconsistent age dependence for hirsutism once reproductive age is considered [19]. Differences in age distributions and phenotype composition across studies likely explain why some series report age-related changes in endocrine or clinical features while others do not.

Health awareness in our participants showed a moderate positive correlation with education level (r = 0.47, p < 0 xss=removed xss=removed>

Chi-square analyses of categorical variables reinforced the importance of adiposity. BMI category was significantly associated with PCOS status (χ² = 10.66, df = 3, p = 0.014); the obese stratum carried a disproportionate share of PCOS cases (≈22% in the obese group versus lower proportions in other strata). This is concordant with large observational series and meta-analyses that document a higher prevalence of overweight and obesity among women with PCOS and an increased cardiometabolic risk burden in obese PCOS subgroups [16, 21]. The relationship between obesity and PCOS is likely bidirectional, obesity exacerbates the metabolic and reproductive phenotypes of PCOS, while PCOS-associated metabolic dysfunction may predispose to weight gain, which supports the public-health emphasis on weight management in PCOS care [16, 21].

We observed a borderline association between urban residence and PCOS (χ² = 3.87, df = 1, p = 0.049) with higher case frequency among urban dwellers (12.7% urban vs 4.3% rural). Urban–rural differences in PCOS prevalence have been reported in several settings and are commonly attributed to lifestyle factors (dietary patterns, sedentary behaviour), higher obesity prevalence in urban populations, differences in environmental exposures, and disparities in access to diagnostic services that influence case detection [19]. While our finding is consistent with an urban excess, it is important to note that detection bias (greater health-seeking or diagnostic access in urban areas) could contribute to the observed difference as much as true etiologic variation.

Education level and marital status were not significantly associated with PCOS status in our sample. The absence of an association between education and PCOS, despite the strong education–awareness link, suggests that while education improves knowledge and possibly health behaviour, it does not directly alter underlying disease risk within the constraints of our cross-sectional design. Similarly, marital status did not stratify PCOS prevalence, which aligns with prior reports showing mixed or no relationships between marital status and PCOS when sociodemographic confounders are considered.

Strengths of our analysis include the concurrent assessment of clinical, anthropometric and endocrine measures and the use of both correlation and categorical association tests to probe relationships. Limitations include the cross-sectional design, which precludes causal inference; possible selection bias related to the recruitment setting; and potential residual confounding (for example, by ethnicity, phenotype subgroup, or unmeasured metabolic variables such as insulin resistance) that may modulate the observed associations. Additionally, heterogeneity in hormonal assay timing and single-timepoint sampling may attenuate relationships with pulsatile hormones such as LH.

Conclusion

In Abia State, Nigeria, we found a PCOS prevalence of 9.6 %, modest awareness levels, and significant links with obesity and urban residence. Our findings reinforce the link between obesity and PCOS and show that hirsutism is more tightly associated with gonadotrophin imbalance than with BMI per se. Education emerged as an important determinant of PCOS awareness, while urban residence may convey higher PCOS prevalence or detection. These results support integrated clinical approaches that address weight management, endocrine evaluation and targeted health education to improve recognition and management of PCOS. Our findings are broadly consonant with Nigerian and broader African literature, though region-specific nuances (e.g. urban–rural differences, educational influences) emerge. The results underscore the need for enhanced public education, screening strategies tied to adiposity risk, and health system strengthening to detect and manage PCOS early—especially because of its potential long-term reproductive and metabolic consequences. Future research should further delineate PCOS phenotypes in Nigeria and assess intervention outcomes in this context.

References

Clearly Auctoresonline and particularly Psychology and Mental Health Care Journal is dedicated to improving health care services for individuals and populations. The editorial boards' ability to efficiently recognize and share the global importance of health literacy with a variety of stakeholders. Auctoresonline publishing platform can be used to facilitate of optimal client-based services and should be added to health care professionals' repertoire of evidence-based health care resources.

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Virginia E. Koenig

Journal of Clinical Cardiology and Cardiovascular Intervention The submission and review process was adequate. However I think that the publication total value should have been enlightened in early fases. Thank you for all.

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Delcio G Silva Junior

Journal of Women Health Care and Issues By the present mail, I want to say thank to you and tour colleagues for facilitating my published article. Specially thank you for the peer review process, support from the editorial office. I appreciate positively the quality of your journal.

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Ziemlé Clément Méda

Journal of Clinical Research and Reports I would be very delighted to submit my testimonial regarding the reviewer board and the editorial office. The reviewer board were accurate and helpful regarding any modifications for my manuscript. And the editorial office were very helpful and supportive in contacting and monitoring with any update and offering help. It was my pleasure to contribute with your promising Journal and I am looking forward for more collaboration.

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Mina Sherif Soliman Georgy

We would like to thank the Journal of Thoracic Disease and Cardiothoracic Surgery because of the services they provided us for our articles. The peer-review process was done in a very excellent time manner, and the opinions of the reviewers helped us to improve our manuscript further. The editorial office had an outstanding correspondence with us and guided us in many ways. During a hard time of the pandemic that is affecting every one of us tremendously, the editorial office helped us make everything easier for publishing scientific work. Hope for a more scientific relationship with your Journal.

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Layla Shojaie

The peer-review process which consisted high quality queries on the paper. I did answer six reviewers’ questions and comments before the paper was accepted. The support from the editorial office is excellent.

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Sing-yung Wu

Journal of Neuroscience and Neurological Surgery. I had the experience of publishing a research article recently. The whole process was simple from submission to publication. The reviewers made specific and valuable recommendations and corrections that improved the quality of my publication. I strongly recommend this Journal.

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Orlando Villarreal

Dr. Katarzyna Byczkowska My testimonial covering: "The peer review process is quick and effective. The support from the editorial office is very professional and friendly. Quality of the Clinical Cardiology and Cardiovascular Interventions is scientific and publishes ground-breaking research on cardiology that is useful for other professionals in the field.

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Katarzyna Byczkowska

Thank you most sincerely, with regard to the support you have given in relation to the reviewing process and the processing of my article entitled "Large Cell Neuroendocrine Carcinoma of The Prostate Gland: A Review and Update" for publication in your esteemed Journal, Journal of Cancer Research and Cellular Therapeutics". The editorial team has been very supportive.

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Anthony Kodzo-Grey Venyo

Testimony of Journal of Clinical Otorhinolaryngology: work with your Reviews has been a educational and constructive experience. The editorial office were very helpful and supportive. It was a pleasure to contribute to your Journal.

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Pedro Marques Gomes

Dr. Bernard Terkimbi Utoo, I am happy to publish my scientific work in Journal of Women Health Care and Issues (JWHCI). The manuscript submission was seamless and peer review process was top notch. I was amazed that 4 reviewers worked on the manuscript which made it a highly technical, standard and excellent quality paper. I appreciate the format and consideration for the APC as well as the speed of publication. It is my pleasure to continue with this scientific relationship with the esteem JWHCI.

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Bernard Terkimbi Utoo

This is an acknowledgment for peer reviewers, editorial board of Journal of Clinical Research and Reports. They show a lot of consideration for us as publishers for our research article “Evaluation of the different factors associated with side effects of COVID-19 vaccination on medical students, Mutah university, Al-Karak, Jordan”, in a very professional and easy way. This journal is one of outstanding medical journal.

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Prof Sherif W Mansour

Dear Hao Jiang, to Journal of Nutrition and Food Processing We greatly appreciate the efficient, professional and rapid processing of our paper by your team. If there is anything else we should do, please do not hesitate to let us know. On behalf of my co-authors, we would like to express our great appreciation to editor and reviewers.

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Hao Jiang

As an author who has recently published in the journal "Brain and Neurological Disorders". I am delighted to provide a testimonial on the peer review process, editorial office support, and the overall quality of the journal. The peer review process at Brain and Neurological Disorders is rigorous and meticulous, ensuring that only high-quality, evidence-based research is published. The reviewers are experts in their fields, and their comments and suggestions were constructive and helped improve the quality of my manuscript. The review process was timely and efficient, with clear communication from the editorial office at each stage. The support from the editorial office was exceptional throughout the entire process. The editorial staff was responsive, professional, and always willing to help. They provided valuable guidance on formatting, structure, and ethical considerations, making the submission process seamless. Moreover, they kept me informed about the status of my manuscript and provided timely updates, which made the process less stressful. The journal Brain and Neurological Disorders is of the highest quality, with a strong focus on publishing cutting-edge research in the field of neurology. The articles published in this journal are well-researched, rigorously peer-reviewed, and written by experts in the field. The journal maintains high standards, ensuring that readers are provided with the most up-to-date and reliable information on brain and neurological disorders. In conclusion, I had a wonderful experience publishing in Brain and Neurological Disorders. The peer review process was thorough, the editorial office provided exceptional support, and the journal's quality is second to none. I would highly recommend this journal to any researcher working in the field of neurology and brain disorders.

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Dr Shiming Tang

Dear Agrippa Hilda, Journal of Neuroscience and Neurological Surgery, Editorial Coordinator, I trust this message finds you well. I want to extend my appreciation for considering my article for publication in your esteemed journal. I am pleased to provide a testimonial regarding the peer review process and the support received from your editorial office. The peer review process for my paper was carried out in a highly professional and thorough manner. The feedback and comments provided by the authors were constructive and very useful in improving the quality of the manuscript. This rigorous assessment process undoubtedly contributes to the high standards maintained by your journal.

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Raed Mualem

International Journal of Clinical Case Reports and Reviews. I strongly recommend to consider submitting your work to this high-quality journal. The support and availability of the Editorial staff is outstanding and the review process was both efficient and rigorous.

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Andreas Filippaios

Thank you very much for publishing my Research Article titled “Comparing Treatment Outcome Of Allergic Rhinitis Patients After Using Fluticasone Nasal Spray And Nasal Douching" in the Journal of Clinical Otorhinolaryngology. As Medical Professionals we are immensely benefited from study of various informative Articles and Papers published in this high quality Journal. I look forward to enriching my knowledge by regular study of the Journal and contribute my future work in the field of ENT through the Journal for use by the medical fraternity. The support from the Editorial office was excellent and very prompt. I also welcome the comments received from the readers of my Research Article.

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Dr Suramya Dhamija

Dear Erica Kelsey, Editorial Coordinator of Cancer Research and Cellular Therapeutics Our team is very satisfied with the processing of our paper by your journal. That was fast, efficient, rigorous, but without unnecessary complications. We appreciated the very short time between the submission of the paper and its publication on line on your site.

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Bruno Chauffert

I am very glad to say that the peer review process is very successful and fast and support from the Editorial Office. Therefore, I would like to continue our scientific relationship for a long time. And I especially thank you for your kindly attention towards my article. Have a good day!

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Baheci Selen

"We recently published an article entitled “Influence of beta-Cyclodextrins upon the Degradation of Carbofuran Derivatives under Alkaline Conditions" in the Journal of “Pesticides and Biofertilizers” to show that the cyclodextrins protect the carbamates increasing their half-life time in the presence of basic conditions This will be very helpful to understand carbofuran behaviour in the analytical, agro-environmental and food areas. We greatly appreciated the interaction with the editor and the editorial team; we were particularly well accompanied during the course of the revision process, since all various steps towards publication were short and without delay".

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Jesus Simal-Gandara

I would like to express my gratitude towards you process of article review and submission. I found this to be very fair and expedient. Your follow up has been excellent. I have many publications in national and international journal and your process has been one of the best so far. Keep up the great work.

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Douglas Miyazaki

We are grateful for this opportunity to provide a glowing recommendation to the Journal of Psychiatry and Psychotherapy. We found that the editorial team were very supportive, helpful, kept us abreast of timelines and over all very professional in nature. The peer review process was rigorous, efficient and constructive that really enhanced our article submission. The experience with this journal remains one of our best ever and we look forward to providing future submissions in the near future.

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Dr Griffith

I am very pleased to serve as EBM of the journal, I hope many years of my experience in stem cells can help the journal from one way or another. As we know, stem cells hold great potential for regenerative medicine, which are mostly used to promote the repair response of diseased, dysfunctional or injured tissue using stem cells or their derivatives. I think Stem Cell Research and Therapeutics International is a great platform to publish and share the understanding towards the biology and translational or clinical application of stem cells.

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Dr Tong Ming Liu

I would like to give my testimony in the support I have got by the peer review process and to support the editorial office where they were of asset to support young author like me to be encouraged to publish their work in your respected journal and globalize and share knowledge across the globe. I really give my great gratitude to your journal and the peer review including the editorial office.

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Husain Taha Radhi

I am delighted to publish our manuscript entitled "A Perspective on Cocaine Induced Stroke - Its Mechanisms and Management" in the Journal of Neuroscience and Neurological Surgery. The peer review process, support from the editorial office, and quality of the journal are excellent. The manuscripts published are of high quality and of excellent scientific value. I recommend this journal very much to colleagues.

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S Munshi

Dr.Tania Muñoz, My experience as researcher and author of a review article in The Journal Clinical Cardiology and Interventions has been very enriching and stimulating. The editorial team is excellent, performs its work with absolute responsibility and delivery. They are proactive, dynamic and receptive to all proposals. Supporting at all times the vast universe of authors who choose them as an option for publication. The team of review specialists, members of the editorial board, are brilliant professionals, with remarkable performance in medical research and scientific methodology. Together they form a frontline team that consolidates the JCCI as a magnificent option for the publication and review of high-level medical articles and broad collective interest. I am honored to be able to share my review article and open to receive all your comments.

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Tania Munoz

“The peer review process of JPMHC is quick and effective. Authors are benefited by good and professional reviewers with huge experience in the field of psychology and mental health. The support from the editorial office is very professional. People to contact to are friendly and happy to help and assist any query authors might have. Quality of the Journal is scientific and publishes ground-breaking research on mental health that is useful for other professionals in the field”.

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George Varvatsoulias

Dear editorial department: On behalf of our team, I hereby certify the reliability and superiority of the International Journal of Clinical Case Reports and Reviews in the peer review process, editorial support, and journal quality. Firstly, the peer review process of the International Journal of Clinical Case Reports and Reviews is rigorous, fair, transparent, fast, and of high quality. The editorial department invites experts from relevant fields as anonymous reviewers to review all submitted manuscripts. These experts have rich academic backgrounds and experience, and can accurately evaluate the academic quality, originality, and suitability of manuscripts. The editorial department is committed to ensuring the rigor of the peer review process, while also making every effort to ensure a fast review cycle to meet the needs of authors and the academic community. Secondly, the editorial team of the International Journal of Clinical Case Reports and Reviews is composed of a group of senior scholars and professionals with rich experience and professional knowledge in related fields. The editorial department is committed to assisting authors in improving their manuscripts, ensuring their academic accuracy, clarity, and completeness. Editors actively collaborate with authors, providing useful suggestions and feedback to promote the improvement and development of the manuscript. We believe that the support of the editorial department is one of the key factors in ensuring the quality of the journal. Finally, the International Journal of Clinical Case Reports and Reviews is renowned for its high- quality articles and strict academic standards. The editorial department is committed to publishing innovative and academically valuable research results to promote the development and progress of related fields. The International Journal of Clinical Case Reports and Reviews is reasonably priced and ensures excellent service and quality ratio, allowing authors to obtain high-level academic publishing opportunities in an affordable manner. I hereby solemnly declare that the International Journal of Clinical Case Reports and Reviews has a high level of credibility and superiority in terms of peer review process, editorial support, reasonable fees, and journal quality. Sincerely, Rui Tao.

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Rui Tao

Clinical Cardiology and Cardiovascular Interventions I testity the covering of the peer review process, support from the editorial office, and quality of the journal.

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Khurram Arshad

Clinical Cardiology and Cardiovascular Interventions, we deeply appreciate the interest shown in our work and its publication. It has been a true pleasure to collaborate with you. The peer review process, as well as the support provided by the editorial office, have been exceptional, and the quality of the journal is very high, which was a determining factor in our decision to publish with you.

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Gomez Barriga Maria Dolores

The peer reviewers process is quick and effective, the supports from editorial office is excellent, the quality of journal is high. I would like to collabroate with Internatioanl journal of Clinical Case Reports and Reviews journal clinically in the future time.

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Lin Shaw Chin

Clinical Cardiology and Cardiovascular Interventions, I would like to express my sincerest gratitude for the trust placed in our team for the publication in your journal. It has been a true pleasure to collaborate with you on this project. I am pleased to inform you that both the peer review process and the attention from the editorial coordination have been excellent. Your team has worked with dedication and professionalism to ensure that your publication meets the highest standards of quality. We are confident that this collaboration will result in mutual success, and we are eager to see the fruits of this shared effort.

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Maria Dolores Gomez Barriga

Dear Dr. Jessica Magne, Editorial Coordinator 0f Clinical Cardiology and Cardiovascular Interventions, I hope this message finds you well. I want to express my utmost gratitude for your excellent work and for the dedication and speed in the publication process of my article titled "Navigating Innovation: Qualitative Insights on Using Technology for Health Education in Acute Coronary Syndrome Patients." I am very satisfied with the peer review process, the support from the editorial office, and the quality of the journal. I hope we can maintain our scientific relationship in the long term.

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Dr Maria Dolores Gomez Barriga

Dear Monica Gissare, - Editorial Coordinator of Nutrition and Food Processing. ¨My testimony with you is truly professional, with a positive response regarding the follow-up of the article and its review, you took into account my qualities and the importance of the topic¨.

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Dr Maria Regina Penchyna Nieto

Dear Dr. Jessica Magne, Editorial Coordinator 0f Clinical Cardiology and Cardiovascular Interventions, The review process for the article “The Handling of Anti-aggregants and Anticoagulants in the Oncologic Heart Patient Submitted to Surgery” was extremely rigorous and detailed. From the initial submission to the final acceptance, the editorial team at the “Journal of Clinical Cardiology and Cardiovascular Interventions” demonstrated a high level of professionalism and dedication. The reviewers provided constructive and detailed feedback, which was essential for improving the quality of our work. Communication was always clear and efficient, ensuring that all our questions were promptly addressed. The quality of the “Journal of Clinical Cardiology and Cardiovascular Interventions” is undeniable. It is a peer-reviewed, open-access publication dedicated exclusively to disseminating high-quality research in the field of clinical cardiology and cardiovascular interventions. The journal's impact factor is currently under evaluation, and it is indexed in reputable databases, which further reinforces its credibility and relevance in the scientific field. I highly recommend this journal to researchers looking for a reputable platform to publish their studies.

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Dr Marcelo Flavio Gomes Jardim Filho

Dear Editorial Coordinator of the Journal of Nutrition and Food Processing! "I would like to thank the Journal of Nutrition and Food Processing for including and publishing my article. The peer review process was very quick, movement and precise. The Editorial Board has done an extremely conscientious job with much help, valuable comments and advices. I find the journal very valuable from a professional point of view, thank you very much for allowing me to be part of it and I would like to participate in the future!”

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Zsuzsanna Bene

Dealing with The Journal of Neurology and Neurological Surgery was very smooth and comprehensive. The office staff took time to address my needs and the response from editors and the office was prompt and fair. I certainly hope to publish with this journal again.Their professionalism is apparent and more than satisfactory. Susan Weiner

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Dr Susan Weiner

My Testimonial Covering as fellowing: Lin-Show Chin. The peer reviewers process is quick and effective, the supports from editorial office is excellent, the quality of journal is high. I would like to collabroate with Internatioanl journal of Clinical Case Reports and Reviews.

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Lin-Show Chin

My experience publishing in Psychology and Mental Health Care was exceptional. The peer review process was rigorous and constructive, with reviewers providing valuable insights that helped enhance the quality of our work. The editorial team was highly supportive and responsive, making the submission process smooth and efficient. The journal's commitment to high standards and academic rigor makes it a respected platform for quality research. I am grateful for the opportunity to publish in such a reputable journal.

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Sonila Qirko

My experience publishing in International Journal of Clinical Case Reports and Reviews was exceptional. I Come forth to Provide a Testimonial Covering the Peer Review Process and the editorial office for the Professional and Impartial Evaluation of the Manuscript.

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Luiz Sellmann

I would like to offer my testimony in the support. I have received through the peer review process and support the editorial office where they are to support young authors like me, encourage them to publish their work in your esteemed journals, and globalize and share knowledge globally. I really appreciate your journal, peer review, and editorial office.

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Zhao Jia

Dear Agrippa Hilda- Editorial Coordinator of Journal of Neuroscience and Neurological Surgery, "The peer review process was very quick and of high quality, which can also be seen in the articles in the journal. The collaboration with the editorial office was very good."

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Thomas Urban

I would like to express my sincere gratitude for the support and efficiency provided by the editorial office throughout the publication process of my article, “Delayed Vulvar Metastases from Rectal Carcinoma: A Case Report.” I greatly appreciate the assistance and guidance I received from your team, which made the entire process smooth and efficient. The peer review process was thorough and constructive, contributing to the overall quality of the final article. I am very grateful for the high level of professionalism and commitment shown by the editorial staff, and I look forward to maintaining a long-term collaboration with the International Journal of Clinical Case Reports and Reviews.

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Cristina Berriozabal

To Dear Erin Aust, I would like to express my heartfelt appreciation for the opportunity to have my work published in this esteemed journal. The entire publication process was smooth and well-organized, and I am extremely satisfied with the final result. The Editorial Team demonstrated the utmost professionalism, providing prompt and insightful feedback throughout the review process. Their clear communication and constructive suggestions were invaluable in enhancing my manuscript, and their meticulous attention to detail and dedication to quality are truly commendable. Additionally, the support from the Editorial Office was exceptional. From the initial submission to the final publication, I was guided through every step of the process with great care and professionalism. The team's responsiveness and assistance made the entire experience both easy and stress-free. I am also deeply impressed by the quality and reputation of the journal. It is an honor to have my research featured in such a respected publication, and I am confident that it will make a meaningful contribution to the field.

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Dr Tewodros Kassahun Tarekegn

"I am grateful for the opportunity of contributing to [International Journal of Clinical Case Reports and Reviews] and for the rigorous review process that enhances the quality of research published in your esteemed journal. I sincerely appreciate the time and effort of your team who have dedicatedly helped me in improvising changes and modifying my manuscript. The insightful comments and constructive feedback provided have been invaluable in refining and strengthening my work".

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Dr Shweta Tiwari

I thank the ‘Journal of Clinical Research and Reports’ for accepting this article for publication. This is a rigorously peer reviewed journal which is on all major global scientific data bases. I note the review process was prompt, thorough and professionally critical. It gave us an insight into a number of important scientific/statistical issues. The review prompted us to review the relevant literature again and look at the limitations of the study. The peer reviewers were open, clear in the instructions and the editorial team was very prompt in their communication. This journal certainly publishes quality research articles. I would recommend the journal for any future publications.

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Dr Farooq Wandroo

Dear Jessica Magne, with gratitude for the joint work. Fast process of receiving and processing the submitted scientific materials in “Clinical Cardiology and Cardiovascular Interventions”. High level of competence of the editors with clear and correct recommendations and ideas for enriching the article.

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Dr Anyuta Ivanova

We found the peer review process quick and positive in its input. The support from the editorial officer has been very agile, always with the intention of improving the article and taking into account our subsequent corrections.

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Dr David Vinyes

My article, titled 'No Way Out of the Smartphone Epidemic Without Considering the Insights of Brain Research,' has been republished in the International Journal of Clinical Case Reports and Reviews. The review process was seamless and professional, with the editors being both friendly and supportive. I am deeply grateful for their efforts.

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Gertraud Teuchert-Noodt

To Dear Erin Aust – Editorial Coordinator of Journal of General Medicine and Clinical Practice! I declare that I am absolutely satisfied with your work carried out with great competence in following the manuscript during the various stages from its receipt, during the revision process to the final acceptance for publication. Thank Prof. Elvira Farina

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Dr Elvira Farina

Dear Jessica, and the super professional team of the ‘Clinical Cardiology and Cardiovascular Interventions’ I am sincerely grateful to the coordinated work of the journal team for the no problem with the submission of my manuscript: “Cardiometabolic Disorders in A Pregnant Woman with Severe Preeclampsia on the Background of Morbid Obesity (Case Report).” The review process by 5 experts was fast, and the comments were professional, which made it more specific and academic, and the process of publication and presentation of the article was excellent. I recommend that my colleagues publish articles in this journal, and I am interested in further scientific cooperation. Sincerely and best wishes, Dr. Oleg Golyanovskiy.

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Dr Oleg Golyanovski

Dear Ashley Rosa, Editorial Coordinator of the journal - Psychology and Mental Health Care. " The process of obtaining publication of my article in the Psychology and Mental Health Journal was positive in all areas. The peer review process resulted in a number of valuable comments, the editorial process was collaborative and timely, and the quality of this journal has been quickly noticed, resulting in alternative journals contacting me to publish with them." Warm regards, Susan Anne Smith, PhD. Australian Breastfeeding Association.

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Dr Susan Anne Smith

Dear Jessica Magne, Editorial Coordinator, Clinical Cardiology and Cardiovascular Interventions, Auctores Publishing LLC. I appreciate the journal (JCCI) editorial office support, the entire team leads were always ready to help, not only on technical front but also on thorough process. Also, I should thank dear reviewers’ attention to detail and creative approach to teach me and bring new insights by their comments. Surely, more discussions and introduction of other hemodynamic devices would provide better prevention and management of shock states. Your efforts and dedication in presenting educational materials in this journal are commendable. Best wishes from, Farahnaz Fallahian.

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Dr Farahnaz Fallahian

Dear Maria Emerson, Editorial Coordinator, International Journal of Clinical Case Reports and Reviews, Auctores Publishing LLC. I am delighted to have published our manuscript, "Acute Colonic Pseudo-Obstruction (ACPO): A rare but serious complication following caesarean section." I want to thank the editorial team, especially Maria Emerson, for their prompt review of the manuscript, quick responses to queries, and overall support. Yours sincerely Dr. Victor Olagundoye.

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Dr Victor Olagundoye

Dear Ashley Rosa, Editorial Coordinator, International Journal of Clinical Case Reports and Reviews. Many thanks for publishing this manuscript after I lost confidence the editors were most helpful, more than other journals Best wishes from, Susan Anne Smith, PhD. Australian Breastfeeding Association.

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Dr Susan Anne Smith

Dear Agrippa Hilda, Editorial Coordinator, Journal of Neuroscience and Neurological Surgery. The entire process including article submission, review, revision, and publication was extremely easy. The journal editor was prompt and helpful, and the reviewers contributed to the quality of the paper. Thank you so much! Eric Nussbaum, MD

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Dr Eric S Nussbaum

Dr Hala Al Shaikh This is to acknowledge that the peer review process for the article ’ A Novel Gnrh1 Gene Mutation in Four Omani Male Siblings, Presentation and Management ’ sent to the International Journal of Clinical Case Reports and Reviews was quick and smooth. The editorial office was prompt with easy communication.

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Hala Al Shaikh

Dear Erin Aust, Editorial Coordinator, Journal of General Medicine and Clinical Practice. We are pleased to share our experience with the “Journal of General Medicine and Clinical Practice”, following the successful publication of our article. The peer review process was thorough and constructive, helping to improve the clarity and quality of the manuscript. We are especially thankful to Ms. Erin Aust, the Editorial Coordinator, for her prompt communication and continuous support throughout the process. Her professionalism ensured a smooth and efficient publication experience. The journal upholds high editorial standards, and we highly recommend it to fellow researchers seeking a credible platform for their work. Best wishes By, Dr. Rakhi Mishra.

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Dr Rakhi Mishra

Dear Jessica Magne, Editorial Coordinator, Clinical Cardiology and Cardiovascular Interventions, Auctores Publishing LLC. The peer review process of the journal of Clinical Cardiology and Cardiovascular Interventions was excellent and fast, as was the support of the editorial office and the quality of the journal. Kind regards Walter F. Riesen Prof. Dr. Dr. h.c. Walter F. Riesen.

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Dr Walter F Riesen

Dear Ashley Rosa, Editorial Coordinator, International Journal of Clinical Case Reports and Reviews, Auctores Publishing LLC. Thank you for publishing our article, Exploring Clozapine's Efficacy in Managing Aggression: A Multiple Single-Case Study in Forensic Psychiatry in the international journal of clinical case reports and reviews. We found the peer review process very professional and efficient. The comments were constructive, and the whole process was efficient. On behalf of the co-authors, I would like to thank you for publishing this article. With regards, Dr. Jelle R. Lettinga.

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Dr Jelle Lettinga

Dear Clarissa Eric, Editorial Coordinator, Journal of Clinical Case Reports and Studies, I would like to express my deep admiration for the exceptional professionalism demonstrated by your journal. I am thoroughly impressed by the speed of the editorial process, the substantive and insightful reviews, and the meticulous preparation of the manuscript for publication. Additionally, I greatly appreciate the courteous and immediate responses from your editorial office to all my inquiries. Best Regards, Dariusz Ziora

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Dariusz Ziora

Dear Chrystine Mejia, Editorial Coordinator, Journal of Neurodegeneration and Neurorehabilitation, Auctores Publishing LLC, We would like to thank the editorial team for the smooth and high-quality communication leading up to the publication of our article in the Journal of Neurodegeneration and Neurorehabilitation. The reviewers have extensive knowledge in the field, and their relevant questions helped to add value to our publication. Kind regards, Dr. Ravi Shrivastava.

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Dr Ravi Shrivastava

Dear Clarissa Eric, Editorial Coordinator, Journal of Clinical Case Reports and Studies, Auctores Publishing LLC, USA Office: +1-(302)-520-2644. I would like to express my sincere appreciation for the efficient and professional handling of my case report by the ‘Journal of Clinical Case Reports and Studies’. The peer review process was not only fast but also highly constructive—the reviewers’ comments were clear, relevant, and greatly helped me improve the quality and clarity of my manuscript. I also received excellent support from the editorial office throughout the process. Communication was smooth and timely, and I felt well guided at every stage, from submission to publication. The overall quality and rigor of the journal are truly commendable. I am pleased to have published my work with Journal of Clinical Case Reports and Studies, and I look forward to future opportunities for collaboration. Sincerely, Aline Tollet, UCLouvain.

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Dr Aline Tollet

Dear Ms. Mayra Duenas, Editorial Coordinator, International Journal of Clinical Case Reports and Reviews. “The International Journal of Clinical Case Reports and Reviews represented the “ideal house” to share with the research community a first experience with the use of the Simeox device for speech rehabilitation. High scientific reputation and attractive website communication were first determinants for the selection of this Journal, and the following submission process exceeded expectations: fast but highly professional peer review, great support by the editorial office, elegant graphic layout. Exactly what a dynamic research team - also composed by allied professionals - needs!" From, Chiara Beccaluva, PT - Italy.

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Dr Chiara Giuseppina Beccaluva

Dear Maria Emerson, Editorial Coordinator, we have deeply appreciated the professionalism demonstrated by the International Journal of Clinical Case Reports and Reviews. The reviewers have extensive knowledge of our field and have been very efficient and fast in supporting the process. I am really looking forward to further collaboration. Thanks. Best regards, Dr. Claudio Ligresti

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Dr Claudio Ligresti

Dear Chrystine Mejia, Editorial Coordinator, Journal of Neurodegeneration and Neurorehabilitation. “The peer review process was efficient and constructive, and the editorial office provided excellent communication and support throughout. The journal ensures scientific rigor and high editorial standards, while also offering a smooth and timely publication process. We sincerely appreciate the work of the editorial team in facilitating the dissemination of innovative approaches such as the Bonori Method.” Best regards, Dr. Matteo Bonori.

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Dr Matteo Bonori

I recommend without hesitation submitting relevant papers on medical decision making to the International Journal of Clinical Case Reports and Reviews. I am very grateful to the editorial staff. Maria Emerson was a pleasure to communicate with. The time from submission to publication was an extremely short 3 weeks. The editorial staff submitted the paper to three reviewers. Two of the reviewers commented positively on the value of publishing the paper. The editorial staff quickly recognized the third reviewer’s comments as an unjust attempt to reject the paper. I revised the paper as recommended by the first two reviewers.

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Edouard Kujawski

Dear Maria Emerson, Editorial Coordinator, Journal of Clinical Research and Reports. Thank you for publishing our case report: "Clinical Case of Effective Fetal Stem Cells Treatment in a Patient with Autism Spectrum Disorder" within the "Journal of Clinical Research and Reports" being submitted by the team of EmCell doctors from Kyiv, Ukraine. We much appreciate a professional and transparent peer-review process from Auctores. All research Doctors are so grateful to your Editorial Office and Auctores Publishing support! I amiably wish our article publication maintained a top quality of your International Scientific Journal. My best wishes for a prosperity of the Journal of Clinical Research and Reports. Hope our scientific relationship and cooperation will remain long lasting. Thank you very much indeed. Kind regards, Dr. Andriy Sinelnyk Cell Therapy Center EmCell

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Dr Andriy Sinelnyk

Dear Editorial Team, Clinical Cardiology and Cardiovascular Interventions. It was truly a rewarding experience to work with the journal “Clinical Cardiology and Cardiovascular Interventions”. The peer review process was insightful and encouraging, helping us refine our work to a higher standard. The editorial office offered exceptional support with prompt and thoughtful communication. I highly value the journal’s role in promoting scientific advancement and am honored to be part of it. Best regards, Meng-Jou Lee, MD, Department of Anesthesiology, National Taiwan University Hospital.

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Dr Meng-JouLe

Dear Editorial Team, Journal-Clinical Cardiology and Cardiovascular Interventions, “Publishing my article with Clinical Cardiology and Cardiovascular Interventions has been a highly positive experience. The peer-review process was rigorous yet supportive, offering valuable feedback that strengthened my work. The editorial team demonstrated exceptional professionalism, prompt communication, and a genuine commitment to maintaining the highest scientific standards. I am very pleased with the publication quality and proud to be associated with such a reputable journal.” Warm regards, Dr. Mahmoud Kamal Moustafa Ahmed

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Mahmoud Kamal Moustafa Ahmed

Dear Maria Emerson, Editorial Coordinator of ‘International Journal of Clinical Case Reports and Reviews’, I appreciate the opportunity to publish my article with your journal. The editorial office provided clear communication during the submission and review process, and I found the overall experience professional and constructive. Best regards, Elena Salvatore.

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Dr Elena Salvatore

Dear Mayra Duenas, Editorial Coordinator of ‘International Journal of Clinical Case Reports and Reviews Herewith I confirm an optimal peer review process and a great support of the editorial office of the present journal

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Christoph Maurer

Dear Editorial Team, Clinical Cardiology and Cardiovascular Interventions. I am really grateful for the peers review; their feedback gave me the opportunity to reflect on the message and impact of my work and to ameliorate the article. The editors did a great job in addition by encouraging me to continue with the process of publishing.

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Baciulescu Laura

Dear Cecilia Lilly, Editorial Coordinator, Endocrinology and Disorders, Thank you so much for your quick response regarding reviewing and all process till publishing our manuscript entitled: Prevalence of Pre-Diabetes and its Associated Risk Factors Among Nile College Students, Sudan. Best regards, Dr Mamoun Magzoub.

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Dr Mamoun Magzoub

International Journal of Clinical Case Reports and Reviews is a high quality journal that has a clear and concise submission process. The peer review process was comprehensive and constructive. Support from the editorial office was excellent, since the administrative staff were responsive. The journal provides a fast and timely publication timeline.

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Joel Yat Seng Wong

Dear Maria Emerson, Editorial Coordinator of International Journal of Clinical Case Reports and Reviews, What distinguishes International Journal of Clinical Case Report and Review is not only the scientific rigor of its publications, but the intellectual climate in which research is evaluated. The submission process is refreshingly free of unnecessary formal barriers and bureaucratic rituals that often complicate academic publishing without adding real value. The peer-review system is demanding yet constructive, guided by genuine scientific dialogue rather than hierarchical or authoritarian attitudes. Reviewers act as collaborators in improving the manuscript, not as gatekeepers imposing arbitrary standards. This journal offers a rare balance: high methodological standards combined with a respectful, transparent, and supportive editorial approach. In an era where publishing can feel more burdensome than research itself, this platform restores the original purpose of peer review — to refine ideas, not to obstruct them Prof. Perlat Kapisyzi, FCCP PULMONOLOGIST AND THORACIC IMAGING.

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Dr Perlat Kapisyzi

Dear Grace Pierce, International Journal of Clinical Case Reports and Reviews I appreciate the opportunity to review for Auctore Journal, as the overall editorial process was smooth, transparent and professionally managed. This journal maintains high scientific standards and ensures timely communications with authors, which is truly commendable. I would like to express my special thanks to editor Grace Pierce for his constant guidance, promt responses, and supportive coordination throughout the review process. I am also greatful to Eleanor Bailey from the finance department for her clear communication and efficient handling of all administrative matters. Overall, my experience with Auctore Journal has been highly positive and rewarding. Best regards, Sabita sinha

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Sabita sinha

Dear Mayra Duenas, Editorial Coordinator of the journal IJCCR, I write here a little on my experience as an author submitting to the International Journal of Clinical Case Reports and Reviews (IJCCR). This was my first submission to IJCCR and my manuscript was inherently an outsider’s effort. It attempted to broadly identify and then make some sense of life’s under-appreciated mysteries. I initially had responded to a request for possible submissions. I then contacted IJCCR with a tentative topic for a manuscript. They quickly got back with an approval for the submission, but with a particular requirement that it be medically relevant. I then put together a manuscript and submitted it. After the usual back-and-forth over forms and formality, the manuscript was sent off for reviews. Within 2 weeks I got back 4 reviews which were both helpful and also surprising. Surprising in that the topic was somewhat foreign to medical literature. My subsequent updates in response to the reviewer comments went smoothly and in short order I had a series of proofs to evaluate. All in all, the whole publication process seemed outstanding. It was both helpful in terms of the paper’s content and also in terms of its efficient and friendly communications. Thank you all very much. Sincerely, Ted Christopher, Rochester, NY.

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Dr Ted Christopher